PINK-CO: Lung Ultrasound Signs and Patterns in COVID-19 Pregnant Women
Study Details
Study Description
Brief Summary
SARS-CoV-2 impact on pregnant women is not well known yet. Some authors demonstrated that lung ultrasound can give similar results if compared to chest computed tomography and better results if compared to chest x-rays without radiations and limited risks for mother and fetus.
The Lung Ultrasound Score (LUS) can be used to asses the entity and monitor the evolution of lung impairment.
Some authors described an artifact, the "light beam", as a typical ultrasound sign in COVID-19 positive patients.
With our study we hypothesize to understand the prevalence of this sign and other ultrasound signs in pregnant COVID-19 positive patients.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
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Study Design
Outcome Measures
Primary Outcome Measures
- Light Beam [24 hours after admission]
Evaluate the prevalence of the light beam sign
Secondary Outcome Measures
- Ultrasound patterns [24 hours after admission]
Evaluate the prevalence of ultrasound signs and patterns during pregnancy
- Lung ultrasound score [24 hours after admission]
Evaluate if the Lung ultrasound score relates with the clinical presentation of the patient
- Illness severity [24 hours after admission]
Evaluate if the lung ultrasound score relates with the prognosis
- Length of stay [24 hours after admission]
Evaluate if the lung ultrasound score relates with the length of stay
Eligibility Criteria
Criteria
Inclusion Criteria:
- All pregnant COVID 19 positive patients admitted at our institution who had lung ultrasound performed
Exclusion Criteria:
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are < 18 years old
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history of rheumatic disease
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history of spontaneous pneumothorax
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fibrothorax
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history of thoracic surgery
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no consent given
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | Anesthesiology and Intensive Care Clinic - Department of Medicine - ASUIUD | Udine | Italy | 33100 |
Sponsors and Collaborators
- Azienda Sanitaria-Universitaria Integrata di Udine
Investigators
None specified.Study Documents (Full-Text)
None provided.More Information
Publications
- Bouhemad B, Mongodi S, Via G, Rouquette I. Ultrasound for "lung monitoring" of ventilated patients. Anesthesiology. 2015 Feb;122(2):437-47. doi: 10.1097/ALN.0000000000000558. Review.
- Convissar DL, Gibson LE, Berra L, Bittner EA, Chang MG. Application of Lung Ultrasound During the COVID-19 Pandemic: A Narrative Review. Anesth Analg. 2020 Aug;131(2):345-350. doi: 10.1213/ANE.0000000000004929. Review.
- Li J, Long X, Wang X, Fang F, Lv X, Zhang D, Sun Y, Hu S, Lin Z, Xiong N. Radiology indispensable for tracking COVID-19. Diagn Interv Imaging. 2021 Feb;102(2):69-75. doi: 10.1016/j.diii.2020.11.008. Epub 2020 Nov 24.
- Lichtenstein D. Lung ultrasound in the critically ill. Curr Opin Crit Care. 2014 Jun;20(3):315-22. doi: 10.1097/MCC.0000000000000096. Review.
- Lichter Y, Topilsky Y, Taieb P, Banai A, Hochstadt A, Merdler I, Gal Oz A, Vine J, Goren O, Cohen B, Sapir O, Granot Y, Mann T, Friedman S, Angel Y, Adi N, Laufer-Perl M, Ingbir M, Arbel Y, Matot I, Szekely Y. Lung ultrasound predicts clinical course and outcomes in COVID-19 patients. Intensive Care Med. 2020 Oct;46(10):1873-1883. doi: 10.1007/s00134-020-06212-1. Epub 2020 Aug 28. Erratum in: Intensive Care Med. 2020 Sep 25;:.
- Rasmussen SA, Smulian JC, Lednicky JA, Wen TS, Jamieson DJ. Coronavirus Disease 2019 (COVID-19) and pregnancy: what obstetricians need to know. Am J Obstet Gynecol. 2020 May;222(5):415-426. doi: 10.1016/j.ajog.2020.02.017. Epub 2020 Feb 24. Review.
- Vetrugno L, Bove T, Orso D, Barbariol F, Bassi F, Boero E, Ferrari G, Kong R. Our Italian experience using lung ultrasound for identification, grading and serial follow-up of severity of lung involvement for management of patients with COVID-19. Echocardiography. 2020 Apr;37(4):625-627. doi: 10.1111/echo.14664. Epub 2020 Apr 15. Review.
- CEUR-2021-223