Lymph Node Yield in Colon Cancer Resection Specimens

Sponsor

Bagcilar Training and Research Hospital (Other)

Overall Status

Completed

CT.gov ID

NCT04260139

Collaborator

(none)

Enrollment

Location

Actual Duration (Months)

3.8

Patients Per Site Per Month

Study Details

Study Description

Brief Summary

In this study, we aimed to develop a predictive model of lymph node yield in a series of colon cancer resection specimens with detailed anatomic and surgical technique data.

Condition or Disease	Intervention/Treatment	Phase
Colon Cancer Lymph Node Metastases	Procedure: Calculation of metric variables on the colectomy specimens.

Detailed Description

Lymph node yield in colon resection specimens has been associated with the accuracy of staging and cancer outcomes. It has been proposed that the more central the mesenteric vascular ligation, the greater the nodal yield. However, the optimal number of harvested nodes is still a matter of debate. We prospectively evaluated the relation between specimen properties such as lenght, area, tumor location and pedicle length to the number of harvested nodes and rate of node positivity.

Study Design

Study Type:

Observational

Actual Enrollment :

50 participants

Observational Model:

Cohort

Time Perspective:

Prospective

Official Title:

Macroscopic Evaluation of Colon Cancer Resection Specimens to Predict Metastatic Lymph Node Yield

Actual Study Start Date :

Sep 1, 2019

Actual Primary Completion Date :

Jul 1, 2020

Actual Study Completion Date :

Oct 1, 2020

Outcome Measures

Primary Outcome Measures

Lymph Node Yield in Colon Cancer Resection Specimens [September 2019- November 2020]
Count of lymph node
Lymph Node Yield in Colon Cancer Resection Specimens [September 2019-November 2020]
Involvement of lymph node

Eligibility Criteria

Criteria

Ages Eligible for Study:

18 Years and Older

Sexes Eligible for Study:

All

Accepts Healthy Volunteers:

Inclusion Criteria:

The surgical patients with a histologic diagnosis of colonic neoplasm, Colectomy of any type, including the right hemicolectomy, the left hemicolectomy, the sigmoid resection, segmental colon resection

Exclusion Criteria:

rectal or rectosigmoid cancer colectomy beyond the inclusion criteria for colectomies patients younger than 18 previous colon resection emergency colon resection familial adenomatous polyposis or ulcerative colitis