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MG-MCP2022: Effects of Magnesium Oil Application on the Muscle Contractile Properties

Sponsor
University of Ljubljana (Other)
Overall Status
Recruiting
CT.gov ID
NCT05339308
Collaborator
Masaryk University (Other)
40
Enrollment
2
Locations
2
Arms
5
Anticipated Duration (Months)
20
Patients Per Site
4
Patients Per Site Per Month

Study Details

Study Description

Brief Summary

This study will aim to investigate the effects of magnesium oil administration on skeletal muscle contractile properties.

Condition or Disease Intervention/Treatment Phase
  • Other: Magnesium oil (BetterYou) dermal application
  • Other: Placebo Control
 N/A

Detailed Description

Aim: This study will aim to investigate the effects of magnesium oil administration on skeletal muscle contractile properties (SMcp).

Design: Randomized controlled study

Participants: For this purpose, investigators will recruit 40 recreationally active and healthy adults of both sexes (18-35 years of age).

Methods: The experimental leg (EXP) will receive the 10 sprays of magnesium oil (20 mg per spray) that will be topically applied to the skin covering the knee extensor muscles, whereas the control leg (CON) will receive 10 sprays of natural mineral-free oil. The vastus lateralis SMcp will be measured by using a tensiomyography (TMG) device before application (PRE) and after 10 (POST10), 20 (POST20), 30 (POST30), 40 (POST40), and 50 (POST50) minutes of application onset, respectively.

Study Design

Study Type:
Interventional
Anticipated Enrollment :
40 participants
Allocation:
Randomized
Intervention Model:
Parallel Assignment
Intervention Model Description:
Randomized controlled studyRandomized controlled study
Masking:
Triple (Participant, Investigator, Outcomes Assessor)
Masking Description:
The participants will not be informed about the actual study purpose, while the main investigator will be blinded to the EXP or CON oil administration
Primary Purpose:
Other
Official Title:
Effects of Magnesium Oil Application on the Muscle Contractile Properties
Actual Study Start Date :
May 1, 2022
Anticipated Primary Completion Date :
Sep 1, 2022
Anticipated Study Completion Date :
Oct 1, 2022

Arms and Interventions

Arm Intervention/Treatment
Experimental: Experimental

Magnesium oil application

Other: Magnesium oil (BetterYou) dermal application
10 sprays (200 mg) of magnesium oil (BetterYou) will be applied to skin covering knee extensor muscles. The magnesium oil will be applied only once
Placebo Comparator: Control

Natural mineral-free oil application

Other: Placebo Control
Natural mineral-free oil (10 sprays) will be applied as the control condition. This will be done only once
Other Names:
  • CONTROL

    		•

    Outcome Measures

    Primary Outcome Measures

    1. Skeletal Muscle Contractile Properties [75 minutes]

      Skeletal muscle contractile properties will be measured by using tensiomyography device

    Eligibility Criteria

    Criteria

    Ages Eligible for Study:
    18 Years to 35 Years
    Sexes Eligible for Study:
    All
    Accepts Healthy Volunteers:
    Yes
    Inclusion Criteria:
    • healthy, recreationally active adults, no history of neuromuscular and musculoskeletal diseases
    Exclusion Criteria:
    • if some of the criteria are not met

    Contacts and Locations

    Locations

    Site City State Country Postal Code
    1 Masaryk University Brno Czechia
    2 Faculty of Sport Ljubljana Slovenia 1000

    Sponsors and Collaborators

    • University of Ljubljana
    • Masaryk University

    Investigators

    • Principal Investigator: Armin Paravlic, PhD, Faculty of Sport

    Study Documents (Full-Text)

    None provided.

    More Information

    Publications

    None provided.
    Responsible Party:
    Armin Paravlic, Principal Investigator, University of Ljubljana
    ClinicalTrials.gov Identifier:
    NCT05339308
    Other Study ID Numbers:
    • MG-MCP2022
    First Posted:
    Apr 21, 2022
    Last Update Posted:
    Jul 8, 2022
    Last Verified:
    Jul 1, 2022
    Individual Participant Data (IPD) Sharing Statement:
    No
    Plan to Share IPD:
    No
    Studies a U.S. FDA-regulated Drug Product:
    No
    Studies a U.S. FDA-regulated Device Product:
    No
    Keywords provided by Armin Paravlic, Principal Investigator, University of Ljubljana
    Tensiomyography
    Skeletal Muscle
    Contractile Properties

    Study Results

    No Results Posted as of Jul 8, 2022