Magnetic Resonance Imaging to Detect Signs of Viral Pneumonia in Patients With Coronavirus Infection.
Study Details
Study Description
Brief Summary
Since the onset of the COVID-19 pandemic, the importance of chest computed tomography (CT) in detecting signs of viral pneumonia has become clear from the literature. However, the increased patient flow creates an additional pressure on CT centers. We believe, the use of chest magnetic resonance imaging (MRI) can help to test patients for CОVID-19 when CT scan is not available. Lung MRI may be useful in routing a patient in a difficult epidemiological situation.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
Detailed Description
Currently, with increased load of CT studies, alternative methods of viral pneumonia signs' visualization are required.
Investigators hypothesize that chest MRI could be a test for detecting pulmonary features of COVID-19. They consider using MRI to assess COVID-19 viral pneumonia. Absence of radiation exposure to patients is a clear advantage of MRI.
This is a prospective, observational cohort study assessing patients with suspected COVID-19. It's primary goal is to determine the ability of multiparametric MRI to detect lung abnormalities - ground-glass opacity (GGO), consolidation, "crazy paving" pattern, pleuritis
- in comparison to CT scan. In this study each patient with suspected pneumonia will sequentially undergo both chest CT and MRI during his/her visit. Scan protocols will be identical for each patient. Each participants completed an online questionnaire.
Study Design
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| Patients with suspected pneumonia COVID-19 Chest MRI findings: bilateral, diffuse ground-glass opacity (GGO), consolidation, "crazy paving" pattern, pleuritis. |
Diagnostic Test: Chest MRI
Patients referred by the primary care physician with suspected pneumonia
Other Names:
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| Patients with suspected pneumonia with COVID -19 Chest CT findings: bilateral, diffuse ground-glass opacity (GGO), consolidation, "crazy paving" pattern, pleuritis. |
Diagnostic Test: Chest MRI
Patients referred by the primary care physician with suspected pneumonia
Other Names:
|
Outcome Measures
Primary Outcome Measures
- Number of zones of pulmonary parenchyma corresponding to viral pneumonia detected by chest MRI in comparison with CT scan [Upon completion, up to 1 year]
Expected number - more than two zones
Eligibility Criteria
Criteria
Inclusion Criteria:
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A referral from the attending physician for a chest CT scan
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Suspected pneumonia
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Signed informed consent
-
Over 18 years old
Exclusion Criteria:
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Pregnant or nursing women
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Presence of foreign implanted objects in the body at the scan level (including cardiac pacemakers, spine metalware)
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | Research and Practical Clinical Center for Diagnostics and Telemedicine Technologies of the Moscow Health Care Department | Moscow | Russian Federation | 109029 |
Sponsors and Collaborators
- Research and Practical Clinical Center for Diagnostics and Telemedicine Technologies of the Moscow Health Care Department
Investigators
None specified.Study Documents (Full-Text)
None provided.More Information
Publications
- Eibel R, Herzog P, Dietrich O, Rieger CT, Ostermann H, Reiser MF, Schoenberg SO. Pulmonary abnormalities in immunocompromised patients: comparative detection with parallel acquisition MR imaging and thin-section helical CT. Radiology. 2006 Dec;241(3):880-91. Epub 2006 Oct 10.
- Ekinci A, Yücel Uçarkuş T, Okur A, Öztürk M, Doğan S. MRI of pneumonia in immunocompromised patients: comparison with CT. Diagn Interv Radiol. 2017 Jan-Feb;23(1):22-28. doi: 10.5152/dir.2016.16055.
- Hui DS, I Azhar E, Madani TA, Ntoumi F, Kock R, Dar O, Ippolito G, Mchugh TD, Memish ZA, Drosten C, Zumla A, Petersen E. The continuing 2019-nCoV epidemic threat of novel coronaviruses to global health - The latest 2019 novel coronavirus outbreak in Wuhan, China. Int J Infect Dis. 2020 Feb;91:264-266. doi: 10.1016/j.ijid.2020.01.009. Epub 2020 Jan 14.
- Li M. Chest CT features and their role in COVID-19. Radiol Infect Dis. 2020 Jun;7(2):51-54. doi: 10.1016/j.jrid.2020.04.001. Epub 2020 Apr 16. Review.
- Lutterbey G, Gieseke J, von Falkenhausen M, Morakkabati N, Schild H. Lung MRI at 3.0 T: a comparison of helical CT and high-field MRI in the detection of diffuse lung disease. Eur Radiol. 2005 Feb;15(2):324-8. Epub 2004 Nov 23.
- 2020-2