Management of Perforated Peptic Ulcer
Study Details
Study Description
Brief Summary
Perforated peptic ulcer (PPU) is a common surgical emergency. Exploratory laparotomy and repair with the omental patch are routine surgical intervention till now. In developing counties, laparoscopic repair is still not considered the gold standard in this emergency condition. This study was conducted to evaluate laparoscopic management of PPU in terms of peri-operative outcomes.
Condition or Disease | Intervention/Treatment | Phase |
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Detailed Description
Files of all patients admitted to our hospital with perforated peptic ulcer in the last 4 years and underwent operative management.
Demographic, clinical and perioperative outcomes will be collected tabulated and analyzed.
Study Design
Outcome Measures
Primary Outcome Measures
- Operative time [2 hours]
Time from skin incision to skin closure
- Leakage [5 days]
Leakage from the repair
- Time to return to normal daily activities. [2 weeks]
Time to return to normal daily activities after surgery.
- Perioperative complications [1 month]
Any encountered perioperative complications related to surgical intervention..
Eligibility Criteria
Criteria
Inclusion Criteria: All patients with perforated peptic ulcer admitted to our hospital in last 4 years and underwent surgical intervention.
Exclusion Criteria: Uncompleted files.
Contacts and Locations
Locations
Site | City | State | Country | Postal Code | |
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1 | Qena Faculty of Medicine, South Valley University Hospitals | QinÄ | Egypt |
Sponsors and Collaborators
- South Valley University
Investigators
- Principal Investigator: Abdallah M Taha, MD, South Valley University
Study Documents (Full-Text)
None provided.More Information
Publications
- Bertleff MJ, Halm JA, Bemelman WA, van der Ham AC, van der Harst E, Oei HI, Smulders JF, Steyerberg EW, Lange JF. Randomized clinical trial of laparoscopic versus open repair of the perforated peptic ulcer: the LAMA Trial. World J Surg. 2009 Jul;33(7):1368-73. doi: 10.1007/s00268-009-0054-y.
- Katkhouda N, Mavor E, Mason RJ, Campos GM, Soroushyari A, Berne TV. Laparoscopic repair of perforated duodenal ulcers: outcome and efficacy in 30 consecutive patients. Arch Surg. 1999 Aug;134(8):845-8; discussion 849-50. doi: 10.1001/archsurg.134.8.845.
- Lagoo S, McMahon RL, Kakihara M, Pappas TN, Eubanks S. The sixth decision regarding perforated duodenal ulcer. JSLS. 2002 Oct-Dec;6(4):359-68.
- Lunevicius R, Morkevicius M. Management strategies, early results, benefits, and risk factors of laparoscopic repair of perforated peptic ulcer. World J Surg. 2005 Oct;29(10):1299-310. doi: 10.1007/s00268-005-7705-4.
- Quah GS, Eslick GD, Cox MR. Laparoscopic Repair for Perforated Peptic Ulcer Disease Has Better Outcomes Than Open Repair. J Gastrointest Surg. 2019 Mar;23(3):618-625. doi: 10.1007/s11605-018-4047-8. Epub 2018 Nov 21.
- SVU-MED-SUR011-4-22-10-466