Mannose Binding Lectin Gene Polymorphism Versus Microbial Virulence in the Pathogenesis of Vulvovaginal Candidiasis
Sponsor
Aljazeera Hospital (Other)
Overall Status
Recruiting
CT.gov ID
NCT04552210
Collaborator
Cairo University (Other)
50
1
5.2
9.7
Study Details
Study Description
Brief Summary
The vaginal mucosa is inhabited by both fungal and bacterial microorganisms which normally co-exist with the host in a tightly regulated and commensal manner.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
Detailed Description
Nevertheless, under certain circumstances, this co-existence can turn into a pathologic state followed by symptomatic disease
Study Design
Study Type:
Observational
Anticipated Enrollment
:
50 participants
Observational Model:
Other
Time Perspective:
Prospective
Official Title:
Mannose Binding Lectin Gene Polymorphism Versus Microbial Virulence in the Pathogenesis of Vulvovaginal Candidiasis in Egypt
Actual Study Start Date
:
Sep 16, 2020
Anticipated Primary Completion Date
:
Dec 15, 2020
Anticipated Study Completion Date
:
Feb 20, 2021
Outcome Measures
Primary Outcome Measures
- the number of women who have mutation in MBL2 gene polymorphism [a month]
women who have mutation in MBL2 gene polymorphism
Eligibility Criteria
Criteria
Ages Eligible for Study:
18 Years
to 42 Years
Sexes Eligible for Study:
Female
Inclusion Criteria:
-
- Married females in the reproductive age period. 2. Females complaining of vaginal discharge (whitish and scanty), itching, dyspareunia, pruritis, and signs of vulvovaginitis ie. erythema.
Exclusion Criteria:
- females who attended the same clinic in the same period, matched the cases regarding the age group, without having Candida infection as confirmed by culture of vaginal swabs.
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | Algazeerah | Giza | Egypt |
Sponsors and Collaborators
- Aljazeera Hospital
- Cairo University
Investigators
- Study Chair: Mahmoud Alalfy, Algezeera hospitaland National Research Centre ,Egypt
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.Responsible Party:
Aljazeera Hospital
ClinicalTrials.gov Identifier:
NCT04552210
Other Study ID Numbers:
- Mannose
First Posted:
Sep 17, 2020
Last Update Posted:
Nov 10, 2020
Last Verified:
Nov 1, 2020
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No
Additional relevant MeSH terms: