Measuring Alterations of DNA in Human Blood
Sponsor
University of Rochester (Other)
Overall Status
Completed
CT.gov ID
NCT00178308
Collaborator
Litron Laboratories (Industry)
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1
Study Details
Study Description
Brief Summary
The purpose of this research is to evaluate an automated, laser-based technique for measuring DNA damge resulting from radiation. We want to use controlled exposure on cancer patients to help develop a measurement to test people who may have been accidentally exposed to radiation.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
|
Study Design
Study Type:
Observational
Observational Model:
Defined Population
Time Perspective:
Prospective
Outcome Measures
Primary Outcome Measures
Eligibility Criteria
Criteria
Ages Eligible for Study:
21 Years
to 70 Years
Sexes Eligible for Study:
All
Inclusion Criteria:
-
Male or female, age 21 to 70 years old.
-
Patient undergoing with anti-neoplastic agent(s) known to have genotoxic activity (e.g., cyclophosphamide, 5-FU, cisplatin, Ara-C.
-
X-irradiation may be considered, so long as a substantial fraction of red marrow is exposed (e.g., femur or chest/trunk region);
-
treatment could be ongoing therapy or initial therapy.
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | University of Rochester | Rochester | New York | United States |
Sponsors and Collaborators
- University of Rochester
- Litron Laboratories
Investigators
- Principal Investigator: Yuhchyau Chen, MD, Ph.D, Universtiy of Rochester, Dept of Radiation Oncology
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.Responsible Party:
,
,
ClinicalTrials.gov Identifier:
NCT00178308
Other Study ID Numbers:
- URCC 1702
First Posted:
Sep 15, 2005
Last Update Posted:
Sep 11, 2006
Last Verified:
Sep 1, 2006