Medication Reconciliation in an Emergency Department: How to Prioritize Patients ?

• Sponsor: Groupe Hospitalier Paris Saint Joseph (Other)
• Overall Status: Completed
• CT.gov ID: NCT03955965
• Collaborator: (none)
• Enrollment: 200
• Location: 1
• Actual Duration (Months): 7.5
• Patients Per Site Per Month: 26.7

Study Details

Study Description

Brief Summary

Medication reconciliation has proven its efficiency in improving patients' care, especially for emergency patients.

This study aimed to identify risk factors of unintended medication discrepancies (UMD) in an emergency department. Secondary objectives were to identify the number and type of UMD, correction rate of UMD and the impact of emergency department organisation on UMD.

Condition or Disease	Intervention/Treatment	Phase
Emergency Service, Hospital; Medication Reconciliation	Other: Medication reconciliation

Detailed Description

Emergency patients are at high risk of medication errors, for different reasons: emergency admission, patients who don't know their at-home treatment (polymedicated, cognitive disorders, etc) and who don't have their medical prescriptions available.

Medication reconciliation has proven its efficiency in improving patients' care, especially for emergency patients. However, prioritization is essential to ensure a better efficiency of pharmaceutical resources.

In our center, a pharmacy resident has been assigned to medication reconciliation in the emergency department since November 2017, in collaboration with a clinical pharmacist. Every morning, 3 to 4 patients benefit from medication reconciliation (patients who will be transfered to another unit within our hospital).

The main objective was to identify risk factors of unintended medication discrepancies (UMD) in order to prioritize patients who will benefit from this newly implemented activity.

Secondary objectives were to identify the number and type of UMD, correction rate of UMD and the impact of emergency department organisation on UMD.

All patients who beneficiated from medication reconciliation in the emergency department between November 2017 and April 2018 were included. Were not included patients with a medication reconciliation performed but transfered to another hospital right after the emergency department visit.

This was a retrospective, monocentric, observational study. Number of patients required was 200. Variables collected were:

• demographics (age, sex, lifestyle, comorbidities),

• emergency care variables (date and time of medical care beginning, ambulance arrival, adressing type, medical prescriptions availability, main diagnosis, date and hour of medical prescriptions in the emergency department, prescriber (pharmacy/doctor), destination unit of patients)

• organizational variables (number of daily emergency visits, number of patients hospitalized within the emergency department),

• medical notes information on at-home treatment (number of missing information, of incorrect information, number of prescriptions in at-home treatment)

• medication reconciliation variables (date of medication reconciliation, number of sources of information needed, number of actual prescriptions in at-home treatment, number of intended medication discrepancies, number and type of UMD, time needed for medication reconciliation).

Study Design

• Study Type: Observational
• Actual Enrollment: 200 participants
• Observational Model: Cohort
• Time Perspective: Retrospective
• Official Title: OPTICONCIL: Implementation of Medication Reconciliation Process in an Emergency Department : Which Patients Should be Prioritized and How to Optimize Patients' Therapeutics?
• Actual Study Start Date: Apr 1, 2018
• Actual Primary Completion Date: May 1, 2018
• Actual Study Completion Date: Nov 15, 2018

Arms and Interventions

Arm	Intervention/Treatment
Emergency patients with medication reconciliation All patients who beneficiated from medication reconciliation in the emergency department between November 2017 and April 2018	Other: Medication reconciliation; No intervention was performed other than collecting data on patients' medical files

Outcome Measures

Primary Outcome Measures

1. Variables influencing the number of UMD in the emergency department [Nov2017-Apr2018]

   Variation of the number of UMD for each variable was measured to identify the impact of each factor on medication errors (linear regression). Variables measured were the variables described in the protocol section.

Secondary Outcome Measures

1. Number and type of UMD [Nov2017-Apr2018]

2. Correction rate of UMD [Nov2017-Apr2018]

3. Impact of organizational variables on the number of UMD [Nov2017-Apr2018]

Eligibility Criteria

Criteria

• Ages Eligible for Study: N/A and Older
• Sexes Eligible for Study: All
• Accepts Healthy Volunteers: Yes

Inclusion Criteria:

• All patients who beneficiated from medication reconciliation in the emergency department between November 2017 and April 2018

Exclusion Criteria:

• Patients transfered to another hospital right after the emergency department visit

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	Groupe Hospitalier Paris Saint Joseph	Paris	Ile-de-France	France	75014

Sponsors and Collaborators

• Groupe Hospitalier Paris Saint Joseph

Investigators

• Principal Investigator: Jennifer Corny, PharmD, Pharmacy Department

Study Documents (Full-Text)

None provided.

More Information

Additional Information:

• Medication reconciliation official guidelines

Publications

None provided.

• Responsible Party: Groupe Hospitalier Paris Saint Joseph
• ClinicalTrials.gov Identifier: NCT03955965
• Other Study ID Numbers: OPTICONCIL
• First Posted: May 20, 2019
• Last Update Posted: May 20, 2019
• Last Verified: May 1, 2019

• Individual Participant Data (IPD) Sharing Statement: No
• Plan to Share IPD: No
• Studies a U.S. FDA-regulated Drug Product: No
• Studies a U.S. FDA-regulated Device Product: No
• Additional relevant MeSH terms: Emergencies

Study Results

No Results Posted as of May 20, 2019