MEMENTO: Memorisation of Phonologic Information Among Children With Oral Language Developement Disorder
Study Details
Study Description
Brief Summary
The disorder of oral language development is defined by the delay in language acquisition in children who possess efficient auditory acuity and normal non verbal intellect.
The diversity of language developement disorders depends either in the expressive level or in the receptive level leading to divers syndromes and symptoms. These syndromes and symptoms are regrouped under the name of STOL (Specific Troubles of Oral Language).
In the current project the visual exploitation and learning capability of children presenting a STOL condition will be compared to patients with a normal development. The investigator's hypothesis is as follows: STOL patients for whom the STOL disorder is reduced between 4 and 7 years of age will present a better performance at verbal memorisation, compared to patients with a persistent STOL condition after the age of 6.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
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Study Design
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| STOL group STOL children will be recruited in the neuropediatric unit at the GHICL in Lille. Children will be followed and we will determine if capacities of verbal memory of the children presenting STOL diagnosed at an early stage of their development (before 6 years) are predictive of the evolution of the disorder according to their cognitive profile and more specifically, their language profile as well as their tests performances. The participants' eye movements ( visual world paradigm or eye tracking) will be recorded in order to determine the interplay between linguistic and visual information processing. Patients with a persistent STOL will be identified at the end of the follow up. |
Other: Eye Tracking
Eye tracker will allows the recording of various information concerning eye fixation (number, duration, location) and saccadic eye movement (speed, range, number, duration) in order to determine the interplay between linguistic and visual information processing during tests performance
Other Names:
|
| Control group Children with no language development disorder willing to participate in the study will be recruited at school. The participants' eye movements ( visual world paradigm or eye tracking) will be recorded in order to determine the interplay between linguistic and visual information processing. |
Other: Eye Tracking
Eye tracker will allows the recording of various information concerning eye fixation (number, duration, location) and saccadic eye movement (speed, range, number, duration) in order to determine the interplay between linguistic and visual information processing during tests performance
Other Names:
|
Outcome Measures
Primary Outcome Measures
- Changes from baseline in the score associated to speech-language outcome measured by a scale grouping results of different questionnaires [0,12, 24 months]
We will determine if capacities of verbal memory of the children presenting STOL diagnosed at an early stage of their development (before 6 years) are predictive of the evolution of the disorder according to their cognitive profile and more specifically, their language profile as well as their tests performances. To measure the speech language outcome is necessary to take in consideration the score of more than one test performance.
Secondary Outcome Measures
- Changes from baseline in the Raven's Progressive Matrices (RPM) test [0,12, 24 months]
Raven's Progressive Matrices (RPM) is a test often used in educational settings that is comprised of 60 multiple choice questions. This is a nonverbal test in that the questions are comprised of visual patterns. RPM measures the ability to think clearly about complex ideas and the ability to store and recall information.
- Changes from baseline in the Peabody Picture Vocabulary Test [0,12, 24 months]
The Peabody Picture Vocabulary Test measures an individual's receptive (hearing) vocabulary and provides, at the same time, a quick estimate of verbal ability or scholastic aptitude.
- Changes from baseline in the number repetition test [0,12, 24 months]
- Changes from baseline in the sentences repetition test [0,12, 24 months]
- Changes from baseline in the non-words repetition test [0,12, 24 months]
- Changes from baseline in the children's eye tracking [0,12, 24 months]
It is done in order to determine if their is a relation between the evolution of processes involved in verbal memorisation (cognitive mechanisms in charge of data processing). Eye tracker will allow the recording of information regarding eye fixation (number, duration, location) and saccadic eye movements (speed, range, number, duration) in order to determine the interplay between linguistic and visual information processing during test performances.
Eligibility Criteria
Criteria
Inclusion Criteria for STOL patients:
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Child aged between 45 and 95 months at inclusion
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A score > or equal to 5 percentile on the non verbal intelligence test (PM47)
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Patient diagnosed with STOL by the neuropediatric medical team
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Coverage of the social insurance
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Consent form signed by the parents or the legal representative of the child
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Normal or corrected sight
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Normal hearing
Inclusion Criteria for control patients:
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Child aged between 45 and 95 months on the day of inclusion
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A score > or equal to 5 percentile on the non verbal intelligence test (PM47)
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Child who did not receive any speech therapy
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Coverage of the social insurance
-
Consent form signed by the parents or the legal representative of the child
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Normal or corrected sight
-
Normal hearing
Exclusion Criteria for STOL patients:
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Mother language other than French
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Score < to 5 percentile on the non verbal intelligence test (PM47)
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Child with pervasive developmental disorder
Exclusion Criteria for control patients:
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Mother language other than French
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Score < to 5 percentile on the non verbal intelligence test (PM47)
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Child who received speech therapy
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | Hôpital St Vincent-de-Paul (GHICL) | Lille | Nord-Pas-de-Calais | France | 59000 |
Sponsors and Collaborators
- Lille Catholic University
Investigators
- Principal Investigator: Delphine Fleurion, Psychologist, Groupement des Hôpitaux de l'Institut Catholique de Lille
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- RC-P0029