Improving Patient Memory for Treatment
Study Details
Study Description
Brief Summary
The empirical question to be addressed is: What types of memory support are most potent for patients who are experiencing a mild cognitive impairment (MCI) relative to non-MCI patients?
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
N/A |
Detailed Description
People experiencing mild cognitive impairment (MCI) may benefit from adding memory support to treatment-as-usual. Adding memory support may be an innovative way to improve patient memory for treatment, adherence to treatment and outcome.
The key question is: What types of memory support are most potent for MCI patients relative to non-MCI patients?
The aim of the proposed research is to compare the effectiveness of constructive vs. non-constructive memory supports for people who are experiencing MCI compared to people who are not experiencing MCI.
Hypotheses:
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Overall recall of the content of treatment will be lower in the MCI group relative to the non-MCI group.
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On the one hand, we have evidence from our prior research that constructive memory support is more potent relative to non-constructive memory support. But this research was conducted with adults who did not have MCI. On the other hand, because constructive memory support is more complex to understand, non-constructive memory support may be more effective for MCI patients.
The outcomes are: (1) patient learning behavior coded from a video of the treatment sessions and (2) patient memory for the content of the prior treatment session. We will also collect ratings of the acceptability of the memory supports that are delivered.
Study Design
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| Active Comparator: Constructive memory support Participants will watch videos of a sleep expert delivering treatment components from the Transdiagnostic Sleep and Circadian Intervention (TranS-C). After each video, a team member will deliver constructive memory supports. |
Behavioral: Transdiagnostic sleep and circadian intervention (TranS-C)
TranS-C is a psychosocial treatment that helps people who have sleep and circadian problems to improve their sleep health.
|
| Active Comparator: Non-constructive memory support Participants will watch videos of a sleep expert delivering treatment components from the Transdiagnostic Sleep and Circadian Intervention (TranS-C). After each video, a team member will deliver non-constructive memory supports. |
Behavioral: Transdiagnostic sleep and circadian intervention (TranS-C)
TranS-C is a psychosocial treatment that helps people who have sleep and circadian problems to improve their sleep health.
|
Outcome Measures
Primary Outcome Measures
- Change on the free recall task to assess outcome for constructive memory support [Delivered two times: At the session in which constructive memory supports were used (baseline) and 1 week later. AND at the end of the session in which non-constructive memory supports were used and 1 week later.]
Assesses patient memory for treatment
- Change on the free recall task to assess outcome for non-constructive memory support [Delivered two times: At the end of the session in which non-constructive memory supports were used (baseline) and 1 week later.]
Assesses patient memory for treatment
- Learning behavior exhibited by the patient during the delivery of constructive memory support [One time point: During the treatment session that constructive memory support was delivered]
Coded from video tapes of the treatment session in which constructive memory support was delivered
- Learning behavior exhibited by the patient during the delivery of non-constructive memory support [One time point: During the treatment session in which non-constructive memory support was delivered]
Coded from video tapes of the treatment session in which non-constructive memory support was delivered
Secondary Outcome Measures
- Acceptability of constructive memory support [One time point: At the end of the treatment session in which constructive memory support was delivered]
Participants will be asked to rate the "How acceptable were the memory supports we asked you through this session?" The participant will then provide a rating from "1" Not at all acceptable to "9" Very acceptable.
Other Outcome Measures
- PROMIS-Sleep Disturbance [At baseline]
Assesses perceived functional impairments related to sleep problems using a self-report questionnaire. The minimum value is 8. The maximum value is 40. Higher scores mean more sleep disturbance (worse outcome).
- PROMIS-Sleep-related impairment [At baseline]
Assesses perceived functional impairments related to sleep problems in a self-report questionnaire. The minimum value is 16. The maximum value is 80. Higher scores mean more sleep related problems (worse outcome).
- British Columbia Cognitive Complaints Inventory [At baseline]
Assessed perceived cognitive difficulties, scale consists of 6 items. Scores can range from 0-18 with higher scores indicating higher levels of perceived cognitive difficulties
- Cognitive Failures Questionnaire [At baseline]
Used to assess the frequency with which people experienced cognitive failures. Scores range from 0-100, with higher scores indicating higher levels of cognitive failures.
- Montreal Cognitive Assessment [At baseline]
An assessment of cognitive functioning
- Sleep intake form [At baseline]
An assessment of the sleep and circadian problems experienced by the participant
Eligibility Criteria
Criteria
Inclusion Criteria:
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Participants 60 years and older will be recruited.
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Fluent in English.
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Experiencing some difficulties relating to sleep and circadian functioning and (d) a score of 19-25 on the Montreal Cognitive Assessment (for the MCI group) and score 26-30 on the Montreal Cognitive Assessment (for the non-MCI group) (e) Have a computer to use and an internet connection and (f) be able to attend sessions weekly and on the same day each week.
Exclusion criteria:
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Presence of an active and progressive mental or physical illness or neurological degenerative disease;
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Night shift work >2 nights per week in the past 3 months;
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Not able and willing to participate in and/or complete the assessments and participate in the treatment.
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | University of California, Berkeley | Berkeley | California | United States | 94720-1650 |
Sponsors and Collaborators
- University of California, Berkeley
Investigators
None specified.Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- Protocol 2022-12-15881