The Effect of Liposuction on Menses: a Retrospective Study

Sponsor
Shanghai Jiao Tong University School of Medicine (Other)
Overall Status
Completed
CT.gov ID
NCT04985591
Collaborator
(none)
516
2
56.9

Study Details

Study Description

Brief Summary

The prevalence of obesity nearly tripled from 1975 to 2021, resulting in liposuction, as an effective shaping method, to be performed more frequently. Liposuction is a surgical procedure that uses a specialized instrument to suck fat fragments in the subcutaneous fat layer through a small incision. Analyzing a large sample sizes of patients who had liposuction, we found that some female patients underwent menstrual irregularity after liposuction. In 2004, Carolyn et al. reported several cases in which there was a connection between liposuction and an early onset of menses. Further studies showed that an early onset of menses may be related to the volume of adipose tissue extracted, the amount of anesthesia given, the area of liposuction, and body weight. However, the sample of that study was small, as there were only 17 cases included in the statistical model, and there are few articles in which the impact of liposuction on menses has been studied. To better understand whether menstrual irregularity will occur after liposuction, patients with postmenopausal or preoperative menstrual irregularity were excluded, leaving a sample of 518 female patients to be reviewed. A better understanding of the impact of liposuction on menses may help clinical doctors predict the underlying risk of menstrual irregularity after liposuction and identify individuals at higher risk. The findings may contribute to further understanding of menstrual irregularity.

Condition or Disease Intervention/Treatment Phase
  • Procedure: Liposuction
  • Procedure: Other plastic surgery
Early Phase 1

Study Design

Study Type:
Interventional
Actual Enrollment :
516 participants
Allocation:
Non-Randomized
Intervention Model:
Parallel Assignment
Masking:
None (Open Label)
Primary Purpose:
Prevention
Official Title:
The Effect of Liposuction on Menses: a Retrospective Study
Actual Study Start Date :
Jun 14, 2016
Actual Primary Completion Date :
Mar 12, 2021
Actual Study Completion Date :
Mar 12, 2021

Arms and Interventions

Arm Intervention/Treatment
Experimental: liposuction group

Procedure: Liposuction
A small, inconspicuous incision was made in the liposuction group to dislodge fat out of the body.

Placebo Comparator: Other plastic surgery group

Procedure: Other plastic surgery
Other plastic surgery like blepharoplasty or keloid excision.

Outcome Measures

Primary Outcome Measures

  1. menstrual irregularity [three months]

    to detect any change in the menses during the following 3 months, post surgery

Eligibility Criteria

Criteria

Ages Eligible for Study:
18 Years to 55 Years
Sexes Eligible for Study:
Female
Accepts Healthy Volunteers:
Yes

Inclusion Criteria:patients who were in 18-55 and have a regular menses -

Exclusion Criteria:Patients who were younger than 18 years old or older than 55 years old, who were in the perimenopausal or postmenopausal stage or who had menstrual irregularity before plastic surgery were excluded from both groups.

-

Contacts and Locations

Locations

No locations specified.

Sponsors and Collaborators

  • Shanghai Jiao Tong University School of Medicine

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.
Responsible Party:
Qing-FengLi Li,MD, Professor, Shanghai Jiao Tong University School of Medicine
ClinicalTrials.gov Identifier:
NCT04985591
Other Study ID Numbers:
  • SH9H-2019-T221-2
First Posted:
Aug 2, 2021
Last Update Posted:
Aug 2, 2021
Last Verified:
Jul 1, 2021
Individual Participant Data (IPD) Sharing Statement:
No
Plan to Share IPD:
No
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No
Additional relevant MeSH terms:

Study Results

No Results Posted as of Aug 2, 2021