The Electrophysiological Signature of the Mental Fatigue-induced Impairment in Endurance Performance

Sponsor
Vrije Universiteit Brussel (Other)
Overall Status
Not yet recruiting
CT.gov ID
NCT04719975
Collaborator
(none)
25
1
4
5.9
4.2

Study Details

Study Description

Brief Summary

The purpose of this project is to provide further insights into the neurophysiology behind the MF-induced impairment in endurance performance. The aim is to perform a randomized controlled trial in which we partly replicate studies of Marcora et al. (2009) and Bigliassi et al. (2017), while extensively monitoring brain activity during the entire protocol (i.e. both cognitive and physical tasks) by using EEG.

Condition or Disease Intervention/Treatment Phase
  • Other: Mental Fatigue (Stroop task)
  • Other: Control (Documentary)
N/A

Study Design

Study Type:
Interventional
Anticipated Enrollment :
25 participants
Allocation:
Randomized
Intervention Model:
Crossover Assignment
Intervention Model Description:
Randomized, blinded, counter-balanced, cross-over designRandomized, blinded, counter-balanced, cross-over design
Masking:
Double (Participant, Outcomes Assessor)
Primary Purpose:
Basic Science
Official Title:
The Electrophysiological Signature of the Mental Fatigue-induced Impairment in Endurance Performance
Anticipated Study Start Date :
Feb 1, 2021
Anticipated Primary Completion Date :
Jun 30, 2021
Anticipated Study Completion Date :
Jul 31, 2021

Arms and Interventions

Arm Intervention/Treatment
Experimental: Mental Fatigue (Stroop) - Chair task

Participants will be performing the Chair Task (150 submaximal dynamic knee extensions at 50% of their maximal voluntary contraction (MVC)) when mentally fatigued. A 60 minute variant of the Stroop task will be used to induce the mental fatigue. During the whole trial EEG will be measured.

Other: Mental Fatigue (Stroop task)
A modified Stroop task of approximately 60 min will be used in order to induce mental fatigue (MF). This will be based on their performance during the max test that was conducted during the familiarization session. In this task, which will be partitioned in 4 blocks of 468 stimuli, four colored words ("rood", "blauw", "groen" and "geel") will be presented one at a time on a computer screen. The participants will be required to indicate the color of the word, ignoring the meaning of the word itself.

Placebo Comparator: Control Task (Documentary) - Chair Task

In the control task subjects will have to watch a documentary on the same computer screen as that used for the experimental trial. These documentaries are chosen based on their emotionally neutral, yet engaging content. This will be followed by the Chair Task, During the whole trial EEG will be measured.

Other: Control (Documentary)
In the control task subjects will have to watch a documentary of 60 min on the same computer screen as the one used for the experimental trial. In order to avoid under- and over-arousal the subjects will have the opportunity to choose between several documentaries as proposed by the research team. During the control task physiological and psychological measures will be assessed at the same time points as during the mental fatigue trial.

Experimental: Mental Fatigue (Stroop) - Bike Task

Participants will be performing the Bike Task (a 9 min cycling task performed at 45 rpm with intensity being constant and will be 10% below VT) when mentally fatigued. A 60 minute variant of the Stroop task will be used to induce the mental fatigue. During the whole trial EEG will be measured.

Other: Mental Fatigue (Stroop task)
A modified Stroop task of approximately 60 min will be used in order to induce mental fatigue (MF). This will be based on their performance during the max test that was conducted during the familiarization session. In this task, which will be partitioned in 4 blocks of 468 stimuli, four colored words ("rood", "blauw", "groen" and "geel") will be presented one at a time on a computer screen. The participants will be required to indicate the color of the word, ignoring the meaning of the word itself.

Placebo Comparator: Control task (Documentary) - Bike Task

In the control task subjects will have to watch a documentary on the same computer screen as that used for the experimental trial. These documentaries are chosen based on their emotionally neutral, yet engaging content. This will be followed by the Bike Task, During the whole trial EEG will be measured.

Other: Control (Documentary)
In the control task subjects will have to watch a documentary of 60 min on the same computer screen as the one used for the experimental trial. In order to avoid under- and over-arousal the subjects will have the opportunity to choose between several documentaries as proposed by the research team. During the control task physiological and psychological measures will be assessed at the same time points as during the mental fatigue trial.

Outcome Measures

Primary Outcome Measures

  1. Electroencephalogram data [1 hours 30 minutes - 2 hours]

    During whole of the trials EEG data will be gathered, each trial will last one and a half to two hours. EEG power in delta, theta, alpha, beta band.

  2. Reaction Time Flanker Task [Total of 10 minutes]

    Reaction Time will be assessed during Flanker task

  3. Accuracy Flanker Task [Total of 10 minutes]

    Accuracy will be assessed during Flanker task

  4. Reaction Time Stroop Task [60 minutes]

    Reaction Time will be assessed during Stroop task

  5. Accuracy performance Stroop Task [60 minutes]

    Accuracy will be assessed during Stroop task

Eligibility Criteria

Criteria

Ages Eligible for Study:
18 Years to 35 Years
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
Yes
Inclusion Criteria:
  • Healthy (No neurological or cardiovascular disorders)

  • Male or female

  • No medication

  • Non-smoker

  • Between 18 and 35 years old

  • Recreational athlete population (performance level 2 or 3 for men according to De Pauw et al. (2013) and performance level 2 or 3 for woman according to Decroix et al. (2016)

Exclusion Criteria:
  • Injuries over the last 6 months

  • Suffering from any cardiovascular condition

  • Use of medication

  • Suffering from other health conditions at the time of testing

  • Use of caffeine or alcohol 24 hours prior to each trial

  • Heavy efforts 24 hours prior to each trial

Contacts and Locations

Locations

Site City State Country Postal Code
1 Human Physiology and Sports Physiotherapy Research Group Brussel Elsene Belgium 1050

Sponsors and Collaborators

  • Vrije Universiteit Brussel

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.
Responsible Party:
Romain Meeusen, Principal Investigator, Vrije Universiteit Brussel
ClinicalTrials.gov Identifier:
NCT04719975
Other Study ID Numbers:
  • MF-EEG-MRCP
First Posted:
Jan 22, 2021
Last Update Posted:
Jan 22, 2021
Last Verified:
Jan 1, 2021
Individual Participant Data (IPD) Sharing Statement:
No
Plan to Share IPD:
No
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No
Additional relevant MeSH terms:

Study Results

No Results Posted as of Jan 22, 2021