Measuring Beliefs and Norms About Persons With Mental Illness

Sponsor
Massachusetts General Hospital (Other)
Overall Status
Completed
CT.gov ID
NCT03656770
Collaborator
(none)
1,782
1
10
17.8
100.1

Study Details

Study Description

Brief Summary

Survey experiment to estimate drivers of mental illness stigma

Condition or Disease Intervention/Treatment Phase
  • Other: Survey questionnaire
N/A

Detailed Description

Despite significant advances in scientific understanding of brain and substance use disorders accompanied by significant advances in treatment and improvements in prognosis, mental illness remains highly stigmatized throughout the world. Previous studies suggest that portraying mental illness as treatable can reduce negative attitudes toward persons with mental illness. This randomized controlled trial compares the effects of exposing study participants to vignettes portraying persons with untreated and symptomatic mental illness vs. treated mental illness with complete response vs. treated mental illness with relapse. It is hypothesized, based on prior work, that study participants exposed to vignettes depicting treated mental illness with completed response would have the greatest effect on reducing negative attitudes toward persons with mental illness, followed by treated mental illness with relapse and untreated and symptomatic mental illness.

Study Design

Study Type:
Interventional
Actual Enrollment :
1782 participants
Allocation:
Randomized
Intervention Model:
Parallel Assignment
Masking:
Triple (Participant, Care Provider, Outcomes Assessor)
Primary Purpose:
Other
Official Title:
Measuring Beliefs and Norms About Persons With Mental Illness in Rural Uganda: A Randomized Survey Experiment
Actual Study Start Date :
Dec 13, 2016
Actual Primary Completion Date :
Jun 8, 2018
Actual Study Completion Date :
Jun 8, 2018

Arms and Interventions

Arm Intervention/Treatment
No Intervention: V1: Control

This version of the survey questionnaire depicts a young woman with no symptoms of mental illness.

Experimental: V2: Schizophrenia

As this is a survey experiment, the "intervention" involves random assignment to a survey questionnaire with specific wording. This version of the survey questionnaire depicts a young woman with untreated and symptomatic schizophrenia.

Other: Survey questionnaire
Each version of the questionnaire portrays a young Ugandan woman with different profiles of illness severity, treatment, and treatment response.

Experimental: V3: Schizophrenia + Tx with Response

As this is a survey experiment, the "intervention" involves random assignment to a survey questionnaire with specific wording. This version of the survey questionnaire depicts a young woman with schizophrenia, successfully treated with complete response.

Other: Survey questionnaire
Each version of the questionnaire portrays a young Ugandan woman with different profiles of illness severity, treatment, and treatment response.

Experimental: V4: Schizophrenia + Tx with Relapse

As this is a survey experiment, the "intervention" involves random assignment to a survey questionnaire with specific wording. This version of the survey questionnaire depicts a young woman with schizophrenia, successfully treated with partial relapse.

Other: Survey questionnaire
Each version of the questionnaire portrays a young Ugandan woman with different profiles of illness severity, treatment, and treatment response.

Experimental: Version 5: Bipolar

As this is a survey experiment, the "intervention" involves random assignment to a survey questionnaire with specific wording. This version of the survey questionnaire depicts a young woman with untreated and symptomatic bipolar disorder.

Other: Survey questionnaire
Each version of the questionnaire portrays a young Ugandan woman with different profiles of illness severity, treatment, and treatment response.

Experimental: V6: Bipolar + Tx with Response

As this is a survey experiment, the "intervention" involves random assignment to a survey questionnaire with specific wording. This version of the survey questionnaire depicts a young woman with bipolar disorder, successfully treated with complete response.

Other: Survey questionnaire
Each version of the questionnaire portrays a young Ugandan woman with different profiles of illness severity, treatment, and treatment response.

Experimental: V7: Bipolar + Tx with Relapse

As this is a survey experiment, the "intervention" involves random assignment to a survey questionnaire with specific wording. This version of the survey questionnaire depicts a young woman with bipolar disorder, successfully treated with partial relapse.

Other: Survey questionnaire
Each version of the questionnaire portrays a young Ugandan woman with different profiles of illness severity, treatment, and treatment response.

Experimental: V8: Depression

As this is a survey experiment, the "intervention" involves random assignment to a survey questionnaire with specific wording. This version of the survey questionnaire depicts a young woman with untreated and symptomatic major depressive disorder.

Other: Survey questionnaire
Each version of the questionnaire portrays a young Ugandan woman with different profiles of illness severity, treatment, and treatment response.

Experimental: V9: Depression + Tx with Response

As this is a survey experiment, the "intervention" involves random assignment to a survey questionnaire with specific wording. This version of the survey questionnaire depicts a young woman with major depressive disorder, successfully treated with complete response.

Other: Survey questionnaire
Each version of the questionnaire portrays a young Ugandan woman with different profiles of illness severity, treatment, and treatment response.

Experimental: V10: Depression + Tx with Relapse

As this is a survey experiment, the "intervention" involves random assignment to a survey questionnaire with specific wording. This version of the survey questionnaire depicts a young woman with major depressive disorder, successfully treated with partial relapse.

Other: Survey questionnaire
Each version of the questionnaire portrays a young Ugandan woman with different profiles of illness severity, treatment, and treatment response.

Outcome Measures

Primary Outcome Measures

  1. Social Distance [Immediate (assessed with respect to the study participant's beliefs at a single time point, which is the time at which the survey is administered)]

    Willingness to have the woman portrayed in the vignette to marry into the study participant's family (single item culturally adapted instrument developed specifically for this study)

  2. Perceived Norms about Social Distance [Immediate (assessed with respect to the study participant's beliefs at a single time point, which is the time at which the survey is administered)]

    Study participant's perception of the extent to which other people would be willing to have the woman portrayed in the vignette to marry into their families (single item culturally adapted instrument developed specifically for this study)

  3. Negative Attitudes (Attribution) [Immediate (assessed with respect to the study participant's beliefs at a single time point, which is the time at which the survey is administered)]

    Personal belief that the symptoms of the woman portrayed in the vignette represent divine punishment (single item culturally adapted instrument developed specifically for this study)

  4. Perceived Norms about Negative Attitudes (Attribution) [Immediate (assessed with respect to the study participant's beliefs at a single time point, which is the time at which the survey is administered)]

    Study participant's perception of the extent to which other people believe that the symptoms of the woman portrayed in the vignette represent divine punishment (single item culturally adapted instrument developed specifically for this study)

  5. Negative Attitudes (Shame) [Immediate (assessed with respect to the study participant's beliefs at a single time point, which is the time at which the survey is administered)]

    Personal belief that the symptoms of the woman portrayed in the vignette bring shame upon her family

  6. Perceived Norms about Negative Attitudes (Shame) [Immediate (assessed with respect to the study participant's beliefs at a single time point, which is the time at which the survey is administered)]

    Study participant's perception of the extent to which other people believe that the symptoms of the woman portrayed in the vignette bring shame upon her family (single item culturally adapted instrument developed specifically for this study)

Eligibility Criteria

Criteria

Ages Eligible for Study:
18 Years and Older
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
Yes
Inclusion Criteria:
  • all persons who considered Nyakabare Parish their primary place of residence and who were capable of providing consent
Exclusion Criteria:
  • minors younger than 18 years of age, with the exception of emancipated minors

  • persons who did not consider Nyakabare their primary place of residence, e.g., persons who happened to be visiting Nyakabare at the time of the survey or who owned a home in Nyakabare but spent most of their time outside the parish

  • persons with whom research staff could not communicate, e.g., due to deafness, mutism, or aphasia

  • persons with psychosis, neurological damage, acute intoxication, or other cognitive impairment (all of which were determined informally in the field by non-clinical research staff in consultation with a supervisor)

Contacts and Locations

Locations

Site City State Country Postal Code
1 Mbarara University of Science and Technology Mbarara Uganda

Sponsors and Collaborators

  • Massachusetts General Hospital

Investigators

  • Principal Investigator: Alexander C Tsai, MD, Massachusetts General Hospital

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.
Responsible Party:
Alexander Tsai, Associate Professor of Psychiatry, Massachusetts General Hospital
ClinicalTrials.gov Identifier:
NCT03656770
Other Study ID Numbers:
  • 2013P000395
First Posted:
Sep 4, 2018
Last Update Posted:
Aug 12, 2019
Last Verified:
Aug 1, 2019
Individual Participant Data (IPD) Sharing Statement:
Undecided
Plan to Share IPD:
Undecided
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No
Additional relevant MeSH terms:

Study Results

No Results Posted as of Aug 12, 2019