Metabolic and Infectious Diseases in La Réunion (the REUNION Population-based Study)

Sponsor

Institut National de la Santé Et de la Recherche Médicale, France (Other)

Overall Status

Recruiting

CT.gov ID

NCT05400824

Collaborator

(none)

2,000

Enrollment

Location

Anticipated Duration (Months)

83.3

Patients Per Site Per Month

Study Details

Study Description

Brief Summary

The aim of the present study is to determine the prevalence of cardiometabolic and infectious disease in La Reunion (french oversea department and region of France).

Known or suspected risk factor for these diseases will also be assessed, such as microbiota, cognitive impairement, social inequalities, and genetics.

Condition or Disease	Intervention/Treatment	Phase
Infectious Disease Cardiovascular Diseases General Population Metabolic Disease	Diagnostic Test: Blood, DNA, feces, urine, hair and skin microbiota collection

Detailed Description

Overall, 2000 men and women will be recruited during two years for an extensive clinical examination including a microbiota, blood, hair and DNA collection, cognitive tests, autonomous nervous system assessment, spirometry, pulse wave velocity measurement, a carotid doppler echo tracking.

Study Design

Study Type:

Observational

Anticipated Enrollment :

2000 participants

Observational Model:

Cohort

Time Perspective:

Prospective

Official Title:

Pathologies métaboliques et Infectieuses en Population générale à La Réunion : étude REUNION

Actual Study Start Date :

May 1, 2022

Anticipated Primary Completion Date :

May 1, 2024

Anticipated Study Completion Date :

May 1, 2024

Arms and Interventions

Arm	Intervention/Treatment
general population Observational study of 2000 adult men and women from the general population who will benefit from a free extensive health check up in La Reunion	Diagnostic Test: Blood, DNA, feces, urine, hair and skin microbiota collection See above Other Names: Ewing test Spirometry EKG cognitive, anxiety and depression tests carotid ultrasound pulse wave velocity measurement ankle brachial index measurement

Arm

Intervention/Treatment

general population

Observational study of 2000 adult men and women from the general population who will benefit from a free extensive health check up in La Reunion

Diagnostic Test: Blood, DNA, feces, urine, hair and skin microbiota collection

See above

Other Names:

Ewing test

Spirometry

EKG

cognitive, anxiety and depression tests

carotid ultrasound

pulse wave velocity measurement

ankle brachial index measurement

Outcome Measures

Primary Outcome Measures

Prevalence of cardiometabolic diseases [cross sectional (at inclusion)]
Prevalence rates for diabetes, hypertension, obesity, dyslipidemia, smoking and subclinical atherosclerosis markers
Prevalence of infectious diseases [cross sectional (at inclusion)]
Seroprevalence rates for chikungunya, dengue, zika, covid19

Eligibility Criteria

Criteria

Ages Eligible for Study:

18 Years to 67 Years

Sexes Eligible for Study:

All

Accepts Healthy Volunteers:

Inclusion Criteria:

18-67 years
given consent for genetic analysis,
written consent for participating in the study

Exclusion Criteria:

judicial protection or guardianship

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	Centre Hospitalier Universitaire de La Réunion	La Réunion	Saint-Pierre	France	97448

Sponsors and Collaborators

Institut National de la Santé Et de la Recherche Médicale, France

Investigators

Principal Investigator: Maxime COURNOT, MD, PhD, Institut National de la Santé Et de la Recherche Médicale, France
Study Director: Olivier MEILHAC, PhD, Institut National de la Santé Et de la Recherche Médicale, France
Study Director: Patrick MAVINGUI, PhD, Institut National de la Santé Et de la Recherche Médicale, France