Effect of Elliptical Training on Metabolic Homeostasis in Metabolic Syndrome
Study Details
Study Description
Brief Summary
The growing prevalence of metabolic syndrome (MetS) in the worldwide is becoming a serious health problem and economic burden. MetS has become a crucial risk factor for the development of type 2 diabetes mellitus (T2DM) and cardiovascular diseases (CVD). The rising rates of CVD and diabetes, which are the two leading causes of death. To prevent the progression of MetS to diabetes and CVD, regular physical activity is required.
Elliptical trainer device is a relatively new modality of exercise and is advertised to be superior to a treadmill because of the low joint impact and the more reasonable costs of an elliptical trainer compared to a treadmill. Additional quantitative research is needed to further evaluate the effectiveness of elliptical trainers and the physiological and perceptual responses to the machine.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
N/A |
Detailed Description
Forty sedentary MeTS patients (from both sexes) will be randomly divided to group A and group B.
-Group A (Elliptical training group): This group (n=20) will receive aerobic training on an elliptical trainer for 16 weeks (3 sessions per week). The session will start with 5 minutes warming up at 50 % of maximal heart rate (MHR), 20-minute continuous ET at 70% of MHR, 12 minutes (4×3) intervals at 90% of MHR with a 3-minute active recovery at 70% of MHR between intervals, and finally 5-minute cool-down period at 50% of MHR.
Group B: this group will continue their normal daily physical activities without any additional training
Study Design
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| Experimental: group A patients (n=30) in this group will receive 16 weeks of elliptical training on elliptical trainer, 3 times per week. the training will start with 5 minutes warming up at 50 % of maximal heart rate (MHR), 20-minute continuous ET at 70% of MHR, 12 minutes (4×3) intervals at 90% of MHR with a 3-minute active recovery at 70% of MHR between intervals, and finally 5-minute cool-down period at 50% of MHR |
Behavioral: exercise training on elliptical device
This group (n=30) will receive aerobic training on an elliptical trainer for 16 weeks (3 sessions per week). The session will start with 5 minutes warming up at 50 % of maximal heart rate (MHR), 20-minute continuous ET at 70% of MHR, 12 minutes (4×3) intervals at 90% of MHR with a 3-minute active recovery at 70% of MHR between intervals, and finally 5-minute cool-down period at 50% of MHR
Other Names:
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| Other: Group B (control group) patients (n=30) in this group will receive general advises on maintaining physical activities |
Behavioral: group B (control group)
this group will receive general advises on maintaining physical activities for 16 weeks without any additional supervised training
|
Outcome Measures
Primary Outcome Measures
- Triglycerides [It will be measured after 16 weeks of training]
Triglycerides is one of lipid profile indicators
- high density lipoprotein [It will be measured after 16 weeks of training]
high density lipoprotein is one of lipid profile indicators
Secondary Outcome Measures
- Systolic blood pressure [It will be measured after 16 weeks of training]
It will be measured via Sphygmomanometer
- diastolic blood pressure [It will be measured after 16 weeks of training]
It will be measured via Sphygmomanometer
- Fasting blood glucose [It will be measured after 16 weeks of training]
It will be measured via a blood glucose meter
- Insulin [It will be measured after 16 weeks of training]
it will be measured via a blood sample
- The HOMA-IR (Homeostatic Model Assessment for Insulin Resistance [It will be measured after 16 weeks of training]
HOMA-IR = [fasting insulin (μU/mL) × fasting glucose (mmol)]/22.5
- Waist circumference [It will be measured after 16 weeks of training]
it will be measured by inelastic tape at the umbilicus level
- weight [It will be measured after 16 weeks of training]
the weight scale will be used
- Leg strength test [It will be measured after 16 weeks of training]
will be assessd by leg dynamometer
- % body fat [It will be measured after 16 weeks of training]
percentage of body fat composition
Eligibility Criteria
Criteria
Inclusion Criteria:
- The MeTS subjects who will have three or more of the following criteria: 1) waist circumference more than 102 cm, triglycerides more than 150 mg/dL, 3) blood pressure (BP) more than 130/85 mmHg, 4) high-density lipoprotein (HDL) less than 40 mg/dL, .
Exclusion criteria:
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Renal, pulmonary, cardiac, vascular, respiratory, hepatic, autoimmune disorders.
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Smoker, addictive, cancer, and alcoholic patients.
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Lower limb arthritis or any orthopaedic problem will hinder the training.
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Participation in any type of sport training in the previous 6 months.
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Pregnant or lactating women.
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Patients with thyroid gland dysfunction.
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | Faculty of Physical Therapy Cairo University | Giza | Dokki | Egypt |
Sponsors and Collaborators
- Cairo University
Investigators
- Principal Investigator: Ali Ismail, lecturer, Cairo University
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- P.T.REC/012/002896