Cisplatin With or Without Veliparib in Treating Patients With Recurrent or Metastatic Triple-Negative and/or BRCA Mutation-Associated Breast Cancer With or Without Brain Metastases

• Sponsor: National Cancer Institute (NCI) (NIH)
• Overall Status: Active, not recruiting
• CT.gov ID: NCT02595905
• Collaborator: (none)
• Enrollment: 333
• Locations: 816
• Arms: 2
• Anticipated Duration (Months): 75.8
• Patients Per Site: 0.4
• Patients Per Site Per Month: 0

Study Details

Study Description

Brief Summary

This randomized phase II trial studies how well cisplatin works with or without veliparib in treating patients with triple-negative breast cancer and/or BRCA mutation-associated breast cancer that has come back (recurrent) or has or has not spread to the brain (brain metastases). Drugs used in chemotherapy, such as cisplatin, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. PARPs are proteins that help repair DNA mutations. PARP inhibitors, such as veliparib, can keep PARP from working, so tumor cells can't repair themselves, and they may stop growing. It is not yet known if cisplatin is more effective with or without veliparib in treating patients with triple-negative and/or BRCA mutation-associated breast cancer.

Condition or Disease	Intervention/Treatment	Phase
Metastatic BRCA-Associated Breast Carcinoma; Metastatic Breast Carcinoma; Metastatic Malignant Neoplasm in the Brain; Metastatic Triple-Negative Breast Carcinoma; Recurrent Breast Carcinoma; Stage IV Breast Cancer AJCC v6 and v7	Drug: Cisplatin; Other: Laboratory Biomarker Analysis; Other: Placebo Administration; Drug: Veliparib	Phase 2

Detailed Description

PRIMARY OBJECTIVES:

1. To compare the efficacy of cisplatin with or without ABT-888 (veliparib) on progression-free survival (PFS) in each of the following groups:

Ia. Patients with germline BRCA (gBRCA) mutation-associated breast cancer. Ib. Patients with germline BRCA wild-type breast cancer who have evidence of BRCAness phenotype.

Ic. Patients with germline BRCA wild-type breast cancer who do not have evidence of BRCAness phenotype.

1. To compare the efficacy of cisplatin with or without ABT-888 on PFS in patients with triple negative and/or gBRCA mutation-associated breast cancer and brain metastases. (Brain Metastases Cohort)

SECONDARY OBJECTIVES:

1. For patients with gBRCA mutation associated breast cancer (group "i" above) or triple-negative breast cancer (TNBC) with (group "ii") or without (group "iii") BRCAness phenotype, to compare the efficacy of cisplatin with or without ABT-888 on overall survival (OS), response rate, and clinical benefit rate.

2. To compare the differential benefit of ABT-888 across the three groups using both PFS and OS as outcomes.

3. For patients in the brain metastases cohort, to compare the efficacy of cisplatin with or without ABT-888 on OS.

4. For patients in the brain metastases cohort, to compare the efficacy of cisplatin with or without ABT-888 on intracranial and extracranial response rates (intracranial by Response Assessment Neuro-Oncology Criteria [RANO] and extracranial by Response Evaluation Criteria in Solid Tumors version 1.1 [RECIST 1.1]).

5. To compare toxicities of ABT-888 to placebo in each of the four groups separately.

TRANSLATIONAL OBJECTIVES:

1. To evaluate the impact of homologous recombination deficiency score (independent of other BRCAness markers) on response rate (RR) and PFS in patients treated with chemotherapy versus chemotherapy plus ABT-888.

2. To evaluate the overlap among various markers utilized to define the BRCAness phenotype.

3. To evaluate the combined impact of PAM50 basal subtype and BRCAness phenotype on RR and PFS in patients treated with chemotherapy versus chemotherapy plus ABT-888.

4. To evaluate the impact of BRCA1 mRNA expression (independent other BRCAness markers) on response rate (RR) and PFS in patients treated with chemotherapy versus chemotherapy plus ABT-888.

5. Application of somatic BRCAness phenotype markers on metastatic tumor tissue to identify patients likely to benefit from platinum-based therapy and ABT-888.

6. To determine the overlap of BRCA phenotype (germline BRCA, BRCA-like, non-BRCA-like) with tissue PD-L1 status and to determine if ABT-888 (veliparib) benefit in BRCA-like patients is maintained when adjusting for PD-L1 status.

7. To evaluate circulating tumor cells - homologous recombination deficiency (CTC-HRD) status as a predictive biomarker of response to treatment with cisplatin plus ABT-888 (veliparib) versus cisplatin plus placebo.

8. To evaluate circulating tumor deoxyribonucleic acid (ctDNA) HRR (homologous recombination repair) mutation status as a predictive marker of response to treatment with cisplatin plus ABT-888 (veliparib) versus cisplatin plus placebo.

OUTLINE: Patients are randomized to 1 of 2 treatment arms.

ARM I: Patients receive cisplatin intravenously (IV) over 1 hour on day 1 and placebo orally (PO) twice daily (BID) on days 1-14. Cycles repeat every 21 days in the absence of disease progression or unacceptable toxicity.

ARM II: Patients receive cisplatin IV over 1 hour on day 1 and veliparib PO BID on days 1-14. Cycles repeat every 21 days in the absence of disease progression or unacceptable toxicity.

After completion of study treatment, patients are followed up every 9 weeks for 54 weeks, every 18 weeks until progression, and then every 6 months for up to 5 years after registration.

Study Design

• Study Type: Interventional
• Anticipated Enrollment: 333 participants
• Allocation: Randomized
• Intervention Model: Parallel Assignment
• Masking: None (Open Label)
• Primary Purpose: Treatment
• Official Title: Phase II Randomized Placebo-Controlled Trial of Cisplatin With or Without ABT-888 (Veliparib) in Metastatic Triple-Negative Breast Cancer and/or BRCA Mutation-Associated Breast Cancer, With or Without Brain Metastases
• Actual Study Start Date: Jul 7, 2016
• Anticipated Primary Completion Date: Oct 31, 2022
• Anticipated Study Completion Date: Oct 31, 2022

Arms and Interventions

Arm	Intervention/Treatment
Active Comparator: Arm I (cisplatin and placebo) Patients receive cisplatin IV over 1 hour on day 1 and placebo PO BID on days 1-14. Cycles repeat every 21 days in the absence of disease progression or unacceptable toxicity.	Drug: Cisplatin; Given IV; Other Names: Abiplatin Blastolem Briplatin CDDP Cis-diammine-dichloroplatinum Cis-diamminedichloridoplatinum Cis-diamminedichloro Platinum (II) Cis-diamminedichloroplatinum Cis-dichloroammine Platinum (II) Cis-platinous Diamine Dichloride Cis-platinum Cis-platinum II Cis-platinum II Diamine Dichloride Cismaplat Cisplatina Cisplatinum Cisplatyl Citoplatino Citosin Cysplatyna DDP Lederplatin Metaplatin Neoplatin Peyrone's Chloride Peyrone's Salt Placis Plastistil Platamine Platiblastin Platiblastin-S Platinex Platinol Platinol- AQ Platinol-AQ Platinol-AQ VHA Plus Platinoxan Platinum Platinum Diamminodichloride Platiran Platistin Platosin ; Other: Laboratory Biomarker Analysis; Correlative studies; Other: Placebo Administration; Given PO
Experimental: Arm II (cisplatin and veliparib) Patients receive cisplatin IV over 1 hour on day 1 and veliparib PO BID on days 1-14. Cycles repeat every 21 days in the absence of disease progression or unacceptable toxicity.	Drug: Cisplatin; Given IV; Other Names: Abiplatin Blastolem Briplatin CDDP Cis-diammine-dichloroplatinum Cis-diamminedichloridoplatinum Cis-diamminedichloro Platinum (II) Cis-diamminedichloroplatinum Cis-dichloroammine Platinum (II) Cis-platinous Diamine Dichloride Cis-platinum Cis-platinum II Cis-platinum II Diamine Dichloride Cismaplat Cisplatina Cisplatinum Cisplatyl Citoplatino Citosin Cysplatyna DDP Lederplatin Metaplatin Neoplatin Peyrone's Chloride Peyrone's Salt Placis Plastistil Platamine Platiblastin Platiblastin-S Platinex Platinol Platinol- AQ Platinol-AQ Platinol-AQ VHA Plus Platinoxan Platinum Platinum Diamminodichloride Platiran Platistin Platosin ; Other: Laboratory Biomarker Analysis; Correlative studies; Drug: Veliparib; Given PO; Other Names: ABT-888 PARP-1 inhibitor ABT-888

Outcome Measures

Primary Outcome Measures

1. Progression-free survival (PFS) [Time from registration (randomization) to progression or death due to any cause, assessed up to 5 years]

   Veliparib will be compared to no veliparib in the BRCA mutation-carriers, BRCA mutation-negative BRCAness-like group, and BRCA mutation-negative non-BRCA-like group. A stratified log-rank test will be used to compare PFS between the two arms in an intention to treat (ITT) analysis where stratification is by line of therapy. In the Progressive Brain Metastases Cohort, veliparib will be compared to no veliparib in patients with active brain metastases that are progressive after prior intracranial therapy. A stratified log-rank test will be used to compare PFS between the two arms in an ITT analysis where stratification is by Modified Breast-Graded Prognostic Assessment (GPA) and prior systemic therapies.

Secondary Outcome Measures

1. Overall survival (OS) [Time from registration to death due to any cause, assessed up to a minimum of 5 years]

   Veliparib will be compared to no veliparib in the BRCA mutation-carriers, BRCA mutation-negative BRCAness-like group, and BRCA mutation-negative non-BRCA-like group. A stratified log-rank test will be used to compare OS between the two arms in an ITT analysis where stratification is line by line. In the Progressive Brain Metastases Cohort, veliparib will be compared to no veliparib in patients with active brain metastases that are progressive after prior intracranial therapy. A stratified log-rank test will be used to compare OS between the two arms in an ITT analysis where stratification is by Modified Breast-GPA and prior systemic therapies.

2. Response rate (measurable disease only) [Up to 5 years]

   Response rate will be analyzed for patients with measurable disease. Patients who achieve complete or partial response will be classified as having a response. The primary analyses will be conducted using these binary responses using Fisher's exact test and logistic regression.

3. Clinical benefit rate [Up to 5 years]

   Clinical benefit will be assessed in all patients and will include those with complete or partial response and those with stable disease for 6 months. The primary analyses will be conducted using these binary responses using Fisher's exact test and logistic regression.

Eligibility Criteria

Criteria

• Ages Eligible for Study: 18 Years and Older
• Sexes Eligible for Study: All
• Accepts Healthy Volunteers: No

Inclusion Criteria:

• Patients must have metastatic and/or recurrent (distant or locoregionally recurrent) breast cancer and be HER2 non-over expressing per 2013 American Society of Clinical Oncology (ASCO)-College of American Pathologists (CAP) HER testing guidelines (0 or 1+ by immunohistochemistry [IHC]; and/or HER2 ratio < 2.0 and HER2 copy number < 4 signals/cell by in-situ hybridization [ISH])

• Local Regional Recurrence

• In the breast (after preserving therapy)

• In the chest wall (after mastectomy)

• In the ipsilateral/parasternal/infra-or supraclavicular lymph nodes

• In the skin of the chest wall (not breast)

• In the reconstructed breast

• Patients must also meet at least one of the following criteria:

• Triple negative: histologically confirmed primary and/or metastatic site that is estrogen receptor (ER)-negative (=< 1%), progesterone receptor (PR)-negative (=< 1%), and HER2-negative

• BRCA mutation: previously confirmed deleterious breast cancer 1, early onset (BRCA1) or breast cancer 2, early onset (BRCA2) germline mutation or suspected deleterious BRCA1 or BRCA2 germline mutation if the classification being used is the 5-tier classification; documentation of germline test results are required

• Patients must have measurable or non-measurable disease; patients must have a chest/abdominal/pelvis computed tomography (CT) scan (or positron emission tomography [PET]/CT of diagnostic quality, conventional or spiral) prior to registration; if the patient is unable to undergo CT with IV contrast due to allergy or renal insufficiency, a non-contrast CT may be performed; all scans needed for assessment of measurable disease must be performed within 28 days prior to registration; non-measurable disease must be assessed within 42 days prior to registration; all disease must be assessed and documented on the Baseline Tumor Assessment Form

• Patients must be women or men ≥ 18 years of age

• Patients must have adequate tissue available and must agree to have specimens submitted for germline BRCA deoxyribonucleic acid (DNA) sequencing and other correlative studies

• NOTE: Blood for BRCA mutation testing is to be collected and submitted after registration but before treatment

• Patients must have had =< 1 prior cytotoxic regimen for metastatic disease (unless enrolling in the Progressive Brain Metastases Cohort); note that endocrine and immunotherapies do not count as cytotoxic regimens

• Patients must have completed any prior radiation therapy and hormonal therapy at least 14 days prior to registration

• Patients may receive bisphosphonates or denosumab concurrently with study treatment; if started prior to registration, it must be started at least 7 days prior to registration

• Patients must have recovered to =< grade 2 following a significant adverse event or toxicity attributed to previous anti-cancer treatment except neurotoxicity which must be =< grade 1

• Patients must have a performance status of 0-2 by Zubrod criteria

• Absolute neutrophil count (ANC) of >= 1,500/mL (within 21 days prior to registration); patients must not have had a blood transfusion within 28 days prior to registration

• Hemoglobin >= 10 g/dL (within 21 days prior to registration); patients must not have had a blood transfusion within 28 days prior to registration

• Platelet count >= 100,000/ mL (within 21 days prior to registration); patients must not have had a blood transfusion within 28 days prior to registration

• Bilirubin =< 1.5 mg/dL (or =< 3.0 mg/dL if due to Gilbert's syndrome or if liver metastases are present) (within 21 days prior to registration)

• Alanine aminotransferase (ALT) and aspartate aminotransferase (AST) =< 2.5 x institutional upper limit of normal (IULN) (or =< 5 x IULN if liver metastases are present) (within 21 days prior to registration)

• Patients must have adequate renal function with serum creatinine level =< IULN within 21 days prior to registration

• Patients must have serum chemistries (including potassium and magnesium) within 21 days prior to registration to obtain baseline values

• Patients must be able to swallow whole capsules

• Patients with a history of uncontrolled seizure disorder; including focal or generalized seizure may not have had a seizure within one year prior to registration

• Patients with known brain metastases must either meet the additional criteria and enroll as part of the Progressive Brain Metastases Cohort, or have clinically controlled neurologic symptoms, defined as surgical excision and/or radiation therapy followed by 14 days of stable neurologic function prior to registration; patients with previously incidentally discovered or asymptomatic brain metastasis(es) must receive surgical excision and/or radiation therapy prior to registration; patients with progressive brain metastases following prior treatment are not eligible for the Standard Cohort, but may be considered for the Progressive Brain Metastases Cohort

• Patients must have a complete history and physical examination within 28 days prior to registration

• Patients of childbearing potential must not be pregnant (negative pregnancy test) or nursing due to the possibility of harm to a fetus or nursing infant from this treatment regimen; men and women of reproductive potential must have agreed to use an effective contraceptive method for 6 months after completion of study treatment; a woman is considered to be of "reproductive potential" if she has had menses at any time in the preceding 12 consecutive months; in addition to routine contraceptive methods, "effective contraception" also includes heterosexual celibacy and surgery intended to prevent pregnancy (or with a side-effect of pregnancy prevention) defined as a hysterectomy, bilateral oophorectomy or bilateral tubal ligation; however, if at any point a previously celibate patient chooses to become heterosexually active during the time period for use of contraceptive measures outlined in the protocol, he/she is responsible for beginning contraceptive measures

• No other prior malignancy is allowed except for the following: adequately treated basal cell or squamous cell skin cancer, in situ cervical cancer, adequately treated stage I or II cancer from which the patient is currently in complete remission, or any other cancer from which the patient has been disease free for five years

• Patients must be informed of the investigational nature of this study and must sign and give written informed consent in accordance with institutional and federal guidelines

• As part of the Oncology Patient Enrollment Network (OPEN) registration process the treating institution's identity is provided in order to ensure that the current (within 365 days) date of institutional review board approval for this study had been entered in the system

• Progressive Brain Metastases Cohort

• S1416 is one study with two cohorts; patients who have progressive brain metastases after surgical excision and/or intracranial radiation will be in the Progressive Brain Metastases Cohort and will require a baseline magnetic resonance imaging (MRI); patients with previously treated brain metastases, stable disease and stable neurologic function for 14 days prior to trial registration will be in the Standard Cohort and may obtain MRI of the brain at the physician's discretion; randomization and treatment is the same for both cohorts

• In addition to all of the previous eligibility criteria, patients with progressive brain metastases who do not satisfy the conditions to enroll in the standard cohort (neurologic stability for 14 days following surgery and/or radiation therapy) must also meet the following criteria to enroll as part of the brain metastases cohort:

• Patients with progressive brain metastases must have a baseline brain MRI within 28 days prior to registration; brain metastases must be progressive and >= 10 mm in longest dimension on radiographic imaging AFTER prior intracranial radiation (IR) therapy (i.e., whole brain radiation therapy [WBRT], stereotactic radiosurgery [SRS], gamma knife [GK] or local equivalent); patients must not have evidence of diffuse leptomeningeal disease on brain MRI or by previously documented cerebrospinal fluid (CSF) cytology; discrete dural metastases are permitted; there must be no evidence of hemorrhage or impending herniation on baseline brain imaging; patients with contraindication to gadolinium-enhanced MRI imaging are not eligible

• Patients must be on a stable or decreasing dose of steroids for >= 7 days prior to registration

• If patient had an open brain biopsy, at least 28 days must have elapsed between biopsy and registration

• Patients enrolling in the Progressive Brain Metastases Cohort can have received up to 3 prior lines of cytotoxic chemotherapy for metastatic disease; note that for enrollment in the standard cohort, patients must have had =< 1 prior cytotoxic regimen for metastatic disease

Exclusion Criteria:

• Patients must not have received prior cisplatin or poly (adenosine diphosphate [ADP]-ribose) polymerase (PARP) inhibitors; prior carboplatin in the adjuvant/neoadjuvant setting is allowed, if completed more than 12 months prior to study entry

• Patients must not have received any chemotherapy within 14 days prior to registration

• Patients must not have received any immunotherapy, biologic or any investigational drug within 28 days prior to registration; patients must not have received bevacizumab within 42 days prior to registration

• Patients must not have a clinically relevant hearing impairment >= grade 2

• Patients must not have treatment-related acute myeloid leukemia (AML) (t-AML)/myelodysplastic syndrome (MDS) or features suggestive of AML/MDS

• Patients must not have had prior allogeneic bone marrow transplant or double umbilical cord blood transplantation

• Patients must not have any incidence of or uncontrolled medical illness (e.g. active cardiac symptoms, active systemic infection, etc.) that would limit the patient's ability to participate in the protocol

• Patients must not have baseline peripheral neuropathy that exceeds grade 1

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	Anchorage Associates in Radiation Medicine	Anchorage	Alaska	United States	98508
2	Anchorage Radiation Therapy Center	Anchorage	Alaska	United States	99504
3	Alaska Breast Care and Surgery LLC	Anchorage	Alaska	United States	99508
4	Alaska Oncology and Hematology LLC	Anchorage	Alaska	United States	99508
5	Alaska Women's Cancer Care	Anchorage	Alaska	United States	99508
6	Anchorage Oncology Centre	Anchorage	Alaska	United States	99508
7	Katmai Oncology Group	Anchorage	Alaska	United States	99508
8	Providence Alaska Medical Center	Anchorage	Alaska	United States	99508
9	Mercy Hospital Fort Smith	Fort Smith	Arkansas	United States	72903
10	CHI Saint Vincent Cancer Center Hot Springs	Hot Springs	Arkansas	United States	71913
11	NEA Baptist Memorial Hospital and Fowler Family Cancer Center - Jonesboro	Jonesboro	Arkansas	United States	72401
12	Kaiser Permanente-Anaheim	Anaheim	California	United States	92806
13	Sutter Auburn Faith Hospital	Auburn	California	United States	95602
14	Sutter Cancer Centers Radiation Oncology Services-Auburn	Auburn	California	United States	95603
15	AIS Cancer Center at San Joaquin Community Hospital	Bakersfield	California	United States	93301
16	Kaiser Permanente-Baldwin Park	Baldwin Park	California	United States	91706
17	Kaiser Permanente-Bellflower	Bellflower	California	United States	90706
18	Alta Bates Summit Medical Center-Herrick Campus	Berkeley	California	United States	94704
19	Providence Saint Joseph Medical Center/Disney Family Cancer Center	Burbank	California	United States	91505
20	Mills-Peninsula Medical Center	Burlingame	California	United States	94010
21	Sutter Cancer Centers Radiation Oncology Services-Cameron Park	Cameron Park	California	United States	95682
22	Mercy San Juan Medical Center	Carmichael	California	United States	95608
23	Eden Hospital Medical Center	Castro Valley	California	United States	94546
24	Sutter Davis Hospital	Davis	California	United States	95616
25	Epic Care-Dublin	Dublin	California	United States	94568
26	Mercy Cancer Center - Elk Grove	Elk Grove	California	United States	95758
27	Bay Area Breast Surgeons Inc	Emeryville	California	United States	94608
28	Epic Care Partners in Cancer Care	Emeryville	California	United States	94608
29	Kaiser Permanente-Fontana	Fontana	California	United States	92335
30	Palo Alto Medical Foundation-Fremont	Fremont	California	United States	94538
31	Kaiser Permanente - Harbor City	Harbor City	California	United States	90710
32	Kaiser Permanente-Irvine	Irvine	California	United States	92618
33	Kaiser Permanente Los Angeles Medical Center	Los Angeles	California	United States	90027
34	Kaiser Permanente West Los Angeles	Los Angeles	California	United States	90034
35	Contra Costa Regional Medical Center	Martinez	California	United States	94553-3156
36	Fremont - Rideout Cancer Center	Marysville	California	United States	95901
37	Mercy UC Davis Cancer Center	Merced	California	United States	95340
38	Memorial Medical Center	Modesto	California	United States	95355
39	Palo Alto Medical Foundation-Camino Division	Mountain View	California	United States	94040
40	Palo Alto Medical Foundation-Gynecologic Oncology	Mountain View	California	United States	94040
41	Sutter Cancer Research Consortium	Novato	California	United States	94945
42	Alta Bates Summit Medical Center - Summit Campus	Oakland	California	United States	94609
43	Bay Area Tumor Institute	Oakland	California	United States	94609
44	Kaiser Permanente-Ontario	Ontario	California	United States	91761
45	Saint Joseph Hospital - Orange	Orange	California	United States	92868
46	Palo Alto Medical Foundation Health Care	Palo Alto	California	United States	94301
47	Kaiser Permanente - Panorama City	Panorama City	California	United States	91402
48	Eisenhower Medical Center	Rancho Mirage	California	United States	92270
49	Kaiser Permanente-Riverside	Riverside	California	United States	92505
50	Mercy Cancer Center - Rocklin	Rocklin	California	United States	95765
51	Sutter Cancer Centers Radiation Oncology Services-Roseville	Roseville	California	United States	95661
52	Sutter Roseville Medical Center	Roseville	California	United States	95661
53	Mercy Cancer Center - Sacramento	Sacramento	California	United States	95816
54	Sutter Medical Center Sacramento	Sacramento	California	United States	95816
55	University of California Davis Comprehensive Cancer Center	Sacramento	California	United States	95817
56	Kaiser Permanente-San Diego Mission	San Diego	California	United States	92108
57	Kaiser Permanente-San Diego Zion	San Diego	California	United States	92120
58	California Pacific Medical Center-Pacific Campus	San Francisco	California	United States	94115
59	Kaiser Permanente-San Marcos	San Marcos	California	United States	92078
60	Palo Alto Medical Foundation-Santa Cruz	Santa Cruz	California	United States	95065
61	Sutter Pacific Medical Foundation	Santa Rosa	California	United States	95403
62	Palo Alto Medical Foundation-Sunnyvale	Sunnyvale	California	United States	94086
63	Gene Upshaw Memorial Tahoe Forest Cancer Center	Truckee	California	United States	96161
64	Sutter Cancer Centers Radiation Oncology Services-Vacaville	Vacaville	California	United States	95687
65	Sutter Solano Medical Center/Cancer Center	Vallejo	California	United States	94589
66	Epic Care Cyberknife Center	Walnut Creek	California	United States	94597
67	Kaiser Permanente-Woodland Hills	Woodland Hills	California	United States	91367
68	Woodland Memorial Hospital	Woodland	California	United States	95695
69	Rocky Mountain Cancer Centers-Aurora	Aurora	Colorado	United States	80012
70	The Medical Center of Aurora	Aurora	Colorado	United States	80012
71	University of Colorado Hospital	Aurora	Colorado	United States	80045
72	Boulder Community Hospital	Boulder	Colorado	United States	80301
73	Rocky Mountain Cancer Centers-Boulder	Boulder	Colorado	United States	80304
74	Penrose-Saint Francis Healthcare	Colorado Springs	Colorado	United States	80907
75	Rocky Mountain Cancer Centers-Penrose	Colorado Springs	Colorado	United States	80907
76	UCHealth Memorial Hospital Central	Colorado Springs	Colorado	United States	80909
77	Memorial Hospital North	Colorado Springs	Colorado	United States	80920
78	Denver Health Medical Center	Denver	Colorado	United States	80204
79	National Jewish Health-Main Campus	Denver	Colorado	United States	80206
80	The Women's Imaging Center	Denver	Colorado	United States	80209
81	Porter Adventist Hospital	Denver	Colorado	United States	80210
82	Colorado Blood Cancer Institute	Denver	Colorado	United States	80218
83	Presbyterian - Saint Lukes Medical Center - Health One	Denver	Colorado	United States	80218
84	Rocky Mountain Cancer Centers-Midtown	Denver	Colorado	United States	80218
85	SCL Health Saint Joseph Hospital	Denver	Colorado	United States	80218
86	Rocky Mountain Cancer Centers-Rose	Denver	Colorado	United States	80220
87	Rose Medical Center	Denver	Colorado	United States	80220
88	Mercy Medical Center	Durango	Colorado	United States	81301
89	Southwest Oncology PC	Durango	Colorado	United States	81301
90	Mountain Blue Cancer Care Center - Swedish	Englewood	Colorado	United States	80113
91	Swedish Medical Center	Englewood	Colorado	United States	80113
92	Poudre Valley Hospital	Fort Collins	Colorado	United States	80524
93	Mountain Blue Cancer Care Center	Golden	Colorado	United States	80401
94	National Jewish Health-Western Hematology Oncology	Golden	Colorado	United States	80401
95	Saint Mary's Hospital and Regional Medical Center	Grand Junction	Colorado	United States	81501
96	Grand Valley Oncology	Grand Junction	Colorado	United States	81505
97	North Colorado Medical Center	Greeley	Colorado	United States	80631
98	Rocky Mountain Cancer Centers-Greenwood Village	Greenwood Village	Colorado	United States	80111
99	Good Samaritan Medical Center	Lafayette	Colorado	United States	80026
100	Rocky Mountain Cancer Centers-Lakewood	Lakewood	Colorado	United States	80228
101	Saint Anthony Hospital	Lakewood	Colorado	United States	80228
102	Rocky Mountain Cancer Centers-Littleton	Littleton	Colorado	United States	80120
103	Littleton Adventist Hospital	Littleton	Colorado	United States	80122
104	Rocky Mountain Cancer Centers-Sky Ridge	Lone Tree	Colorado	United States	80124
105	Sky Ridge Medical Center	Lone Tree	Colorado	United States	80124
106	Longmont United Hospital	Longmont	Colorado	United States	80501
107	Rocky Mountain Cancer Centers-Longmont	Longmont	Colorado	United States	80501
108	McKee Medical Center	Loveland	Colorado	United States	80539
109	Parker Adventist Hospital	Parker	Colorado	United States	80138
110	Rocky Mountain Cancer Centers-Parker	Parker	Colorado	United States	80138
111	Saint Mary Corwin Medical Center	Pueblo	Colorado	United States	81004
112	Rocky Mountain Cancer Centers - Pueblo	Pueblo	Colorado	United States	81008
113	National Jewish Health-Northern Hematology Oncology	Thornton	Colorado	United States	80260
114	Rocky Mountain Cancer Centers-Thornton	Thornton	Colorado	United States	80260
115	SCL Health Lutheran Medical Center	Wheat Ridge	Colorado	United States	80033
116	Danbury Hospital	Danbury	Connecticut	United States	06810
117	Greenwich Hospital	Greenwich	Connecticut	United States	06830
118	Middlesex Hospital	Middletown	Connecticut	United States	06457
119	Beebe Medical Center	Lewes	Delaware	United States	19958
120	Delaware Clinical and Laboratory Physicians PA	Newark	Delaware	United States	19713
121	Helen F Graham Cancer Center	Newark	Delaware	United States	19713
122	Medical Oncology Hematology Consultants PA	Newark	Delaware	United States	19713
123	Christiana Care Health System-Christiana Hospital	Newark	Delaware	United States	19718
124	Beebe Health Campus	Rehoboth Beach	Delaware	United States	19971
125	TidalHealth Nanticoke / Allen Cancer Center	Seaford	Delaware	United States	19973
126	Christiana Care Health System-Wilmington Hospital	Wilmington	Delaware	United States	19801
127	Halifax Health Medical Center-Centers for Oncology	Daytona Beach	Florida	United States	32114
128	Memorial Regional Hospital/Joe DiMaggio Children's Hospital	Hollywood	Florida	United States	33021
129	Baptist MD Anderson Cancer Center	Jacksonville	Florida	United States	32207
130	Memorial Hospital West	Pembroke Pines	Florida	United States	33028
131	Cleveland Clinic-Weston	Weston	Florida	United States	33331
132	University Cancer and Blood Center LLC	Athens	Georgia	United States	30607
133	Augusta University Medical Center	Augusta	Georgia	United States	30912
134	Dekalb Medical Center	Decatur	Georgia	United States	30033
135	Lewis Hall Singletary Oncology Center	Thomasville	Georgia	United States	31792
136	South Georgia Medical Center/Pearlman Cancer Center	Valdosta	Georgia	United States	31602
137	Saint Alphonsus Cancer Care Center-Boise	Boise	Idaho	United States	83706
138	Saint Luke's Cancer Institute - Boise	Boise	Idaho	United States	83712
139	Saint Alphonsus Cancer Care Center-Caldwell	Caldwell	Idaho	United States	83605
140	Kootenai Health - Coeur d'Alene	Coeur d'Alene	Idaho	United States	83814
141	Walter Knox Memorial Hospital	Emmett	Idaho	United States	83617
142	Saint Luke's Cancer Institute - Fruitland	Fruitland	Idaho	United States	83619
143	Idaho Urologic Institute-Meridian	Meridian	Idaho	United States	83642
144	Saint Luke's Cancer Institute - Meridian	Meridian	Idaho	United States	83642
145	Saint Alphonsus Medical Center-Nampa	Nampa	Idaho	United States	83686
146	Saint Luke's Cancer Institute - Nampa	Nampa	Idaho	United States	83686
147	Kootenai Clinic Cancer Services - Post Falls	Post Falls	Idaho	United States	83854
148	Kootenai Cancer Clinic	Sandpoint	Idaho	United States	83864
149	Saint Luke's Cancer Institute - Twin Falls	Twin Falls	Idaho	United States	83301
150	Rush - Copley Medical Center	Aurora	Illinois	United States	60504
151	Saint Joseph Medical Center	Bloomington	Illinois	United States	61701
152	Illinois CancerCare-Bloomington	Bloomington	Illinois	United States	61704
153	Illinois CancerCare-Canton	Canton	Illinois	United States	61520
154	Memorial Hospital of Carbondale	Carbondale	Illinois	United States	62902
155	SIH Cancer Institute	Carterville	Illinois	United States	62918
156	Illinois CancerCare-Carthage	Carthage	Illinois	United States	62321
157	Centralia Oncology Clinic	Centralia	Illinois	United States	62801
158	Mount Sinai Hospital Medical Center	Chicago	Illinois	United States	60608
159	University of Chicago Comprehensive Cancer Center	Chicago	Illinois	United States	60637
160	Weiss Memorial Hospital	Chicago	Illinois	United States	60640
161	Carle on Vermilion	Danville	Illinois	United States	61832
162	Cancer Care Specialists of Illinois - Decatur	Decatur	Illinois	United States	62526
163	Decatur Memorial Hospital	Decatur	Illinois	United States	62526
164	Carle Physician Group-Effingham	Effingham	Illinois	United States	62401
165	Crossroads Cancer Center	Effingham	Illinois	United States	62401
166	AMITA Health Alexian Brothers Medical Center	Elk Grove Village	Illinois	United States	60007
167	Illinois CancerCare-Eureka	Eureka	Illinois	United States	61530
168	Illinois CancerCare-Galesburg	Galesburg	Illinois	United States	61401
169	Western Illinois Cancer Treatment Center	Galesburg	Illinois	United States	61401
170	AMITA Health Cancer Institute and Outpatient Center	Hinsdale	Illinois	United States	60521
171	Presence Saint Mary's Hospital	Kankakee	Illinois	United States	60901
172	Illinois CancerCare-Kewanee Clinic	Kewanee	Illinois	United States	61443
173	Illinois CancerCare-Macomb	Macomb	Illinois	United States	61455
174	Carle Physician Group-Mattoon/Charleston	Mattoon	Illinois	United States	61938
175	Loyola University Medical Center	Maywood	Illinois	United States	60153
176	Good Samaritan Regional Health Center	Mount Vernon	Illinois	United States	62864
177	UC Comprehensive Cancer Center at Silver Cross	New Lenox	Illinois	United States	60451
178	Cancer Care Center of O'Fallon	O'Fallon	Illinois	United States	62269
179	University of Chicago Medicine-Orland Park	Orland Park	Illinois	United States	60462
180	Illinois CancerCare-Ottawa Clinic	Ottawa	Illinois	United States	61350
181	Radiation Oncology of Northern Illinois	Ottawa	Illinois	United States	61350
182	Illinois CancerCare-Pekin	Pekin	Illinois	United States	61554
183	OSF Saint Francis Radiation Oncology at Pekin Cancer Treatment Center	Pekin	Illinois	United States	61554
184	Illinois CancerCare-Peoria	Peoria	Illinois	United States	61615
185	OSF Saint Francis Radiation Oncology at Peoria Cancer Center	Peoria	Illinois	United States	61615
186	Methodist Medical Center of Illinois	Peoria	Illinois	United States	61636
187	OSF Saint Francis Medical Center	Peoria	Illinois	United States	61637
188	Illinois CancerCare-Peru	Peru	Illinois	United States	61354
189	Valley Radiation Oncology	Peru	Illinois	United States	61354
190	Illinois CancerCare-Princeton	Princeton	Illinois	United States	61356
191	West Suburban Medical Center	River Forest	Illinois	United States	60305
192	SwedishAmerican Regional Cancer Center/ACT	Rockford	Illinois	United States	61114
193	Genesis Cancer Center - Silvis	Silvis	Illinois	United States	61282
194	Central Illinois Hematology Oncology Center	Springfield	Illinois	United States	62702
195	Southern Illinois University School of Medicine	Springfield	Illinois	United States	62702
196	Springfield Clinic	Springfield	Illinois	United States	62702
197	Memorial Medical Center	Springfield	Illinois	United States	62781
198	Southwest Illinois Health Services LLP	Swansea	Illinois	United States	62226
199	Carle Cancer Center	Urbana	Illinois	United States	61801
200	The Carle Foundation Hospital	Urbana	Illinois	United States	61801
201	Rush-Copley Healthcare Center	Yorkville	Illinois	United States	60560
202	Deaconess Clinic Downtown	Evansville	Indiana	United States	47713
203	Indiana University/Melvin and Bren Simon Cancer Center	Indianapolis	Indiana	United States	46202
204	Sidney and Lois Eskenazi Hospital	Indianapolis	Indiana	United States	46202
205	Springmill Medical Center	Indianapolis	Indiana	United States	46290
206	Franciscan Saint Anthony Health-Michigan City	Michigan City	Indiana	United States	46360
207	Woodland Cancer Care Center	Michigan City	Indiana	United States	46360
208	Memorial Regional Cancer Center Day Road	Mishawaka	Indiana	United States	46545
209	Chancellor Center for Oncology	Newburgh	Indiana	United States	47630
210	Reid Health	Richmond	Indiana	United States	47374
211	Memorial Hospital of South Bend	South Bend	Indiana	United States	46601
212	Mary Greeley Medical Center	Ames	Iowa	United States	50010
213	McFarland Clinic PC - Ames	Ames	Iowa	United States	50010
214	McFarland Clinic PC-Boone	Boone	Iowa	United States	50036
215	Mercy Hospital	Cedar Rapids	Iowa	United States	52403
216	Oncology Associates at Mercy Medical Center	Cedar Rapids	Iowa	United States	52403
217	Medical Oncology and Hematology Associates-West Des Moines	Clive	Iowa	United States	50325
218	Mercy Cancer Center-West Lakes	Clive	Iowa	United States	50325
219	Alegent Health Mercy Hospital	Council Bluffs	Iowa	United States	51503
220	Greater Regional Medical Center	Creston	Iowa	United States	50801
221	Genesis Medical Center - East Campus	Davenport	Iowa	United States	52803
222	Genesis Cancer Care Institute	Davenport	Iowa	United States	52804
223	Iowa Cancer Specialists	Davenport	Iowa	United States	52807
224	Iowa Methodist Medical Center	Des Moines	Iowa	United States	50309
225	Medical Oncology and Hematology Associates-Des Moines	Des Moines	Iowa	United States	50309
226	Broadlawns Medical Center	Des Moines	Iowa	United States	50314
227	Medical Oncology and Hematology Associates-Laurel	Des Moines	Iowa	United States	50314
228	Mercy Medical Center - Des Moines	Des Moines	Iowa	United States	50314
229	Iowa Lutheran Hospital	Des Moines	Iowa	United States	50316
230	McFarland Clinic PC-Trinity Cancer Center	Fort Dodge	Iowa	United States	50501
231	Trinity Regional Medical Center	Fort Dodge	Iowa	United States	50501
232	McFarland Clinic PC-Jefferson	Jefferson	Iowa	United States	50129
233	McFarland Clinic PC-Marshalltown	Marshalltown	Iowa	United States	50158
234	Siouxland Regional Cancer Center	Sioux City	Iowa	United States	51101
235	MercyOne Waterloo Medical Center	Waterloo	Iowa	United States	50702
236	Methodist West Hospital	West Des Moines	Iowa	United States	50266-7700
237	Mercy Medical Center-West Lakes	West Des Moines	Iowa	United States	50266
238	Cancer Center of Kansas - Chanute	Chanute	Kansas	United States	66720
239	Cancer Center of Kansas - Dodge City	Dodge City	Kansas	United States	67801
240	Cancer Center of Kansas - El Dorado	El Dorado	Kansas	United States	67042
241	Cancer Center of Kansas - Fort Scott	Fort Scott	Kansas	United States	66701
242	Central Care Cancer Center - Garden City	Garden City	Kansas	United States	67846
243	Central Care Cancer Center - Great Bend	Great Bend	Kansas	United States	67530
244	Cancer Center of Kansas-Independence	Independence	Kansas	United States	67301
245	Cancer Center of Kansas-Kingman	Kingman	Kansas	United States	67068
246	Lawrence Memorial Hospital	Lawrence	Kansas	United States	66044
247	Kansas Institute of Medicine Cancer and Blood Center	Lenexa	Kansas	United States	66219
248	Minimally Invasive Surgery Hospital	Lenexa	Kansas	United States	66219
249	Cancer Center of Kansas-Liberal	Liberal	Kansas	United States	67905
250	Cancer Center of Kansas-Manhattan	Manhattan	Kansas	United States	66502
251	Cancer Center of Kansas - McPherson	McPherson	Kansas	United States	67460
252	Cancer Center of Kansas - Newton	Newton	Kansas	United States	67114
253	Menorah Medical Center	Overland Park	Kansas	United States	66209
254	Saint Luke's South Hospital	Overland Park	Kansas	United States	66213
255	Cancer Center of Kansas - Parsons	Parsons	Kansas	United States	67357
256	Cancer Center of Kansas - Pratt	Pratt	Kansas	United States	67124
257	Cancer Center of Kansas - Salina	Salina	Kansas	United States	67401
258	Cancer Center of Kansas - Wellington	Wellington	Kansas	United States	67152
259	Associates In Womens Health	Wichita	Kansas	United States	67208
260	Cancer Center of Kansas-Wichita Medical Arts Tower	Wichita	Kansas	United States	67208
261	Ascension Via Christi Hospitals Wichita	Wichita	Kansas	United States	67214
262	Cancer Center of Kansas - Wichita	Wichita	Kansas	United States	67214
263	Cancer Center of Kansas - Winfield	Winfield	Kansas	United States	67156
264	Flaget Memorial Hospital	Bardstown	Kentucky	United States	40004
265	Baptist Health Corbin	Corbin	Kentucky	United States	40701
266	Commonwealth Cancer Center-Corbin	Corbin	Kentucky	United States	40701
267	Oncology Hematology Care Inc-Crestview	Crestview Hills	Kentucky	United States	41017
268	Baptist Health Hardin	Elizabethtown	Kentucky	United States	42701
269	Baptist Health Lexington	Lexington	Kentucky	United States	40503
270	Saint Joseph Radiation Oncology Resource Center	Lexington	Kentucky	United States	40504
271	Saint Joseph Hospital East	Lexington	Kentucky	United States	40509
272	Saint Joseph London	London	Kentucky	United States	40741
273	Jewish Hospital	Louisville	Kentucky	United States	40202
274	Baptist Health Louisville	Louisville	Kentucky	United States	40207
275	Saints Mary and Elizabeth Hospital	Louisville	Kentucky	United States	40215
276	UofL Health Medical Center Northeast	Louisville	Kentucky	United States	40245
277	Baptist Health Madisonville/Merle Mahr Cancer Center	Madisonville	Kentucky	United States	42431
278	Baptist Health Paducah	Paducah	Kentucky	United States	42003
279	Jewish Hospital Medical Center South	Shepherdsville	Kentucky	United States	40165
280	Christus Saint Frances Cabrini Hospital	Alexandria	Louisiana	United States	71301
281	Ochsner Health Center-Summa	Baton Rouge	Louisiana	United States	70809
282	Medical Center of Baton Rouge	Baton Rouge	Louisiana	United States	70816
283	Ochsner High Grove	Baton Rouge	Louisiana	United States	70836
284	Ochsner Medical Center Kenner	Kenner	Louisiana	United States	70065
285	Ochsner LSU Health Monroe Medical Center	Monroe	Louisiana	United States	71202
286	Louisiana State University Health Science Center	New Orleans	Louisiana	United States	70112
287	Ochsner Medical Center Jefferson	New Orleans	Louisiana	United States	70121
288	LSU Health Sciences Center at Shreveport	Shreveport	Louisiana	United States	71103
289	CHRISTUS Highland Medical Center	Shreveport	Louisiana	United States	71105
290	Harold Alfond Center for Cancer Care	Augusta	Maine	United States	04330
291	Eastern Maine Medical Center	Bangor	Maine	United States	04401
292	Lafayette Family Cancer Center-EMMC	Brewer	Maine	United States	04412
293	Penobscot Bay Medical Center	Rockport	Maine	United States	04856
294	Greater Baltimore Medical Center	Baltimore	Maryland	United States	21204
295	Holy Cross Hospital	Silver Spring	Maryland	United States	20910
296	Lahey Hospital and Medical Center	Burlington	Massachusetts	United States	01805
297	Mercy Medical Center	Springfield	Massachusetts	United States	01104
298	Winchester Hospital	Winchester	Massachusetts	United States	01890
299	Hickman Cancer Center	Adrian	Michigan	United States	49221
300	Saint Joseph Mercy Hospital	Ann Arbor	Michigan	United States	48106
301	University of Michigan Comprehensive Cancer Center	Ann Arbor	Michigan	United States	48109
302	Bronson Battle Creek	Battle Creek	Michigan	United States	49017
303	Saint Joseph Mercy Brighton	Brighton	Michigan	United States	48114
304	Trinity Health IHA Medical Group Hematology Oncology - Brighton	Brighton	Michigan	United States	48114
305	Henry Ford Cancer Institute-Downriver	Brownstown	Michigan	United States	48183
306	Saint Joseph Mercy Canton	Canton	Michigan	United States	48188
307	Trinity Health IHA Medical Group Hematology Oncology - Canton	Canton	Michigan	United States	48188
308	Caro Cancer Center	Caro	Michigan	United States	48723
309	Saint Joseph Mercy Chelsea	Chelsea	Michigan	United States	48118
310	Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital	Chelsea	Michigan	United States	48118
311	Hematology Oncology Consultants-Clarkston	Clarkston	Michigan	United States	48346
312	Newland Medical Associates-Clarkston	Clarkston	Michigan	United States	48346
313	Henry Ford Macomb Hospital-Clinton Township	Clinton Township	Michigan	United States	48038
314	Beaumont Hospital - Dearborn	Dearborn	Michigan	United States	48124
315	Henry Ford Medical Center-Fairlane	Dearborn	Michigan	United States	48126
316	Henry Ford Hospital	Detroit	Michigan	United States	48202
317	Ascension Saint John Hospital	Detroit	Michigan	United States	48236
318	Great Lakes Cancer Management Specialists-Doctors Park	East China Township	Michigan	United States	48054
319	Green Bay Oncology - Escanaba	Escanaba	Michigan	United States	49829
320	Beaumont Hospital - Farmington Hills	Farmington Hills	Michigan	United States	48336
321	Genesee Cancer and Blood Disease Treatment Center	Flint	Michigan	United States	48503
322	Genesee Hematology Oncology PC	Flint	Michigan	United States	48503
323	Genesys Hurley Cancer Institute	Flint	Michigan	United States	48503
324	Hurley Medical Center	Flint	Michigan	United States	48503
325	Helen DeVos Children's Hospital at Spectrum Health	Grand Rapids	Michigan	United States	49503
326	Mercy Health Saint Mary's	Grand Rapids	Michigan	United States	49503
327	Spectrum Health at Butterworth Campus	Grand Rapids	Michigan	United States	49503
328	Academic Hematology Oncology Specialists	Grosse Pointe Woods	Michigan	United States	48236
329	Great Lakes Cancer Management Specialists-Van Elslander Cancer Center	Grosse Pointe Woods	Michigan	United States	48236
330	Michigan Breast Specialists-Grosse Pointe Woods	Grosse Pointe Woods	Michigan	United States	48236
331	William Beaumont Hospital-Grosse Pointe	Grosse Pointe	Michigan	United States	48230
332	Allegiance Health	Jackson	Michigan	United States	49201
333	Bronson Methodist Hospital	Kalamazoo	Michigan	United States	49007
334	West Michigan Cancer Center	Kalamazoo	Michigan	United States	49007
335	Borgess Medical Center	Kalamazoo	Michigan	United States	49048
336	Sparrow Hospital	Lansing	Michigan	United States	48912
337	Hope Cancer Clinic	Livonia	Michigan	United States	48154
338	Trinity Health Saint Mary Mercy Livonia Hospital	Livonia	Michigan	United States	48154
339	Great Lakes Cancer Management Specialists-Macomb Medical Campus	Macomb	Michigan	United States	48044
340	Michigan Breast Specialists-Macomb Township	Macomb	Michigan	United States	48044
341	Saint Mary's Oncology/Hematology Associates of Marlette	Marlette	Michigan	United States	48453
342	Monroe Cancer Center	Monroe	Michigan	United States	48162
343	Toledo Clinic Cancer Centers-Monroe	Monroe	Michigan	United States	48162
344	Mercy Health Mercy Campus	Muskegon	Michigan	United States	49444
345	Lakeland Hospital Niles	Niles	Michigan	United States	49120
346	Ascension Providence Hospitals - Novi	Novi	Michigan	United States	48374
347	Henry Ford Medical Center-Columbus	Novi	Michigan	United States	48377
348	21st Century Oncology-Pontiac	Pontiac	Michigan	United States	48341
349	Hope Cancer Center	Pontiac	Michigan	United States	48341
350	Newland Medical Associates-Pontiac	Pontiac	Michigan	United States	48341
351	Saint Joseph Mercy Oakland	Pontiac	Michigan	United States	48341
352	Spectrum Health Reed City Hospital	Reed City	Michigan	United States	49677
353	Great Lakes Cancer Management Specialists-Rochester Hills	Rochester Hills	Michigan	United States	48309
354	Michigan Cancer Specialists	Roseville	Michigan	United States	48066
355	Oakland Colon Rectal Associates	Royal Oak	Michigan	United States	48067
356	Cancer Care Associates PC	Royal Oak	Michigan	United States	48073
357	Comprehensive Medical Center PLLC	Royal Oak	Michigan	United States	48073
358	Hematology Oncology Consultants PC	Royal Oak	Michigan	United States	48073
359	Oakland Medical Group	Royal Oak	Michigan	United States	48073
360	William Beaumont Hospital-Royal Oak	Royal Oak	Michigan	United States	48073
361	Ascension Saint Mary's Hospital	Saginaw	Michigan	United States	48601
362	Oncology Hematology Associates of Saginaw Valley PC	Saginaw	Michigan	United States	48604
363	Lakeland Medical Center Saint Joseph	Saint Joseph	Michigan	United States	49085
364	Marie Yeager Cancer Center	Saint Joseph	Michigan	United States	49085
365	Ascension Providence Hospitals - Southfield	Southfield	Michigan	United States	48075
366	Bhadresh Nayak MD PC-Sterling Heights	Sterling Heights	Michigan	United States	48312
367	Premier Hematology Oncology Care	Sterling Heights	Michigan	United States	48312
368	Mitchell Folbe MD PC	Sterling Heights	Michigan	United States	48314
369	Ascension Saint Joseph Hospital	Tawas City	Michigan	United States	48764
370	Munson Medical Center	Traverse City	Michigan	United States	49684
371	Michigan Institute of Urology-Town Center	Troy	Michigan	United States	48084
372	Claudia BR Herke MD PC	Troy	Michigan	United States	48085
373	William Beaumont Hospital - Troy	Troy	Michigan	United States	48085
374	Hematology Oncology Consultants PC-Troy	Troy	Michigan	United States	48098
375	Advanced Breast Care Center PLLC	Warren	Michigan	United States	48088
376	Great Lakes Cancer Management Specialists-Macomb Professional Building	Warren	Michigan	United States	48093
377	Macomb Hematology Oncology PC	Warren	Michigan	United States	48093
378	Michigan Breast Specialists-Warren	Warren	Michigan	United States	48093
379	Saint John Macomb-Oakland Hospital	Warren	Michigan	United States	48093
380	Henry Ford West Bloomfield Hospital	West Bloomfield	Michigan	United States	48322
381	Saint Mary's Oncology/Hematology Associates of West Branch	West Branch	Michigan	United States	48661
382	Metro Health Hospital	Wyoming	Michigan	United States	49519
383	Huron Gastroenterology PC	Ypsilanti	Michigan	United States	48106
384	Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus	Ypsilanti	Michigan	United States	48197
385	Sanford Joe Lueken Cancer Center	Bemidji	Minnesota	United States	56601
386	Essentia Health Saint Joseph's Medical Center	Brainerd	Minnesota	United States	56401
387	Fairview Ridges Hospital	Burnsville	Minnesota	United States	55337
388	Cambridge Medical Center	Cambridge	Minnesota	United States	55008
389	Mercy Hospital	Coon Rapids	Minnesota	United States	55433
390	Essentia Health - Deer River Clinic	Deer River	Minnesota	United States	56636
391	Essentia Health Saint Mary's - Detroit Lakes Clinic	Detroit Lakes	Minnesota	United States	56501
392	Essentia Health Cancer Center	Duluth	Minnesota	United States	55805
393	Essentia Health Saint Mary's Medical Center	Duluth	Minnesota	United States	55805
394	Miller-Dwan Hospital	Duluth	Minnesota	United States	55805
395	Fairview Southdale Hospital	Edina	Minnesota	United States	55435
396	Lake Region Healthcare Corporation-Cancer Care	Fergus Falls	Minnesota	United States	56537
397	Essentia Health - Fosston	Fosston	Minnesota	United States	56542
398	Unity Hospital	Fridley	Minnesota	United States	55432
399	Essentia Health Hibbing Clinic	Hibbing	Minnesota	United States	55746
400	Fairview Clinics and Surgery Center Maple Grove	Maple Grove	Minnesota	United States	55369
401	Minnesota Oncology Hematology PA-Maplewood	Maplewood	Minnesota	United States	55109
402	Saint John's Hospital - Healtheast	Maplewood	Minnesota	United States	55109
403	Abbott-Northwestern Hospital	Minneapolis	Minnesota	United States	55407
404	Hennepin County Medical Center	Minneapolis	Minnesota	United States	55415
405	Health Partners Inc	Minneapolis	Minnesota	United States	55454
406	Monticello Cancer Center	Monticello	Minnesota	United States	55362
407	New Ulm Medical Center	New Ulm	Minnesota	United States	56073
408	Essentia Health - Park Rapids	Park Rapids	Minnesota	United States	56470
409	Fairview Northland Medical Center	Princeton	Minnesota	United States	55371
410	North Memorial Medical Health Center	Robbinsdale	Minnesota	United States	55422
411	Mayo Clinic in Rochester	Rochester	Minnesota	United States	55905
412	Coborn Cancer Center at Saint Cloud Hospital	Saint Cloud	Minnesota	United States	56303
413	Park Nicollet Clinic - Saint Louis Park	Saint Louis Park	Minnesota	United States	55416
414	Regions Hospital	Saint Paul	Minnesota	United States	55101
415	United Hospital	Saint Paul	Minnesota	United States	55102
416	Essentia Health Sandstone	Sandstone	Minnesota	United States	55072
417	Saint Francis Regional Medical Center	Shakopee	Minnesota	United States	55379
418	Lakeview Hospital	Stillwater	Minnesota	United States	55082
419	Sanford Thief River Falls Medical Center	Thief River Falls	Minnesota	United States	56701
420	Essentia Health Virginia Clinic	Virginia	Minnesota	United States	55792
421	Ridgeview Medical Center	Waconia	Minnesota	United States	55387
422	Rice Memorial Hospital	Willmar	Minnesota	United States	56201
423	Minnesota Oncology Hematology PA-Woodbury	Woodbury	Minnesota	United States	55125
424	Sanford Cancer Center Worthington	Worthington	Minnesota	United States	56187
425	Fairview Lakes Medical Center	Wyoming	Minnesota	United States	55092
426	Baptist Memorial Hospital and Cancer Center-Golden Triangle	Columbus	Mississippi	United States	39705
427	Baptist Cancer Center-Grenada	Grenada	Mississippi	United States	38901
428	Gulfport Memorial Hospital	Gulfport	Mississippi	United States	39502
429	Hattiesburg Clinic - Hematology/Oncology Clinic	Hattiesburg	Mississippi	United States	39401
430	University of Mississippi Medical Center	Jackson	Mississippi	United States	39216
431	Baptist Memorial Hospital and Cancer Center-Union County	New Albany	Mississippi	United States	38652
432	Baptist Memorial Hospital and Cancer Center-Oxford	Oxford	Mississippi	United States	38655
433	Baptist Memorial Hospital and Cancer Center-Desoto	Southhaven	Mississippi	United States	38671
434	Saint Louis Cancer and Breast Institute-Ballwin	Ballwin	Missouri	United States	63011
435	Central Care Cancer Center - Bolivar	Bolivar	Missouri	United States	65613
436	Parkland Health Center-Bonne Terre	Bonne Terre	Missouri	United States	63628
437	Cox Cancer Center Branson	Branson	Missouri	United States	65616
438	Saint Francis Medical Center	Cape Girardeau	Missouri	United States	63703
439	Southeast Cancer Center	Cape Girardeau	Missouri	United States	63703
440	Siteman Cancer Center at West County Hospital	Creve Coeur	Missouri	United States	63141
441	Centerpoint Medical Center LLC	Independence	Missouri	United States	64057
442	Capital Region Southwest Campus	Jefferson City	Missouri	United States	65109
443	Freeman Health System	Joplin	Missouri	United States	64804
444	Mercy Hospital Joplin	Joplin	Missouri	United States	64804
445	Saint Luke's Hospital of Kansas City	Kansas City	Missouri	United States	64111
446	Research Medical Center	Kansas City	Missouri	United States	64132
447	Saint Luke's East - Lee's Summit	Lee's Summit	Missouri	United States	64086
448	Delbert Day Cancer Institute at PCRMC	Rolla	Missouri	United States	65401
449	Mercy Clinic-Rolla-Cancer and Hematology	Rolla	Missouri	United States	65401
450	Heartland Regional Medical Center	Saint Joseph	Missouri	United States	64506
451	Saint Louis Cancer and Breast Institute-South City	Saint Louis	Missouri	United States	63109
452	Washington University School of Medicine	Saint Louis	Missouri	United States	63110
453	Mercy Hospital South	Saint Louis	Missouri	United States	63128
454	Siteman Cancer Center-South County	Saint Louis	Missouri	United States	63129
455	Missouri Baptist Medical Center	Saint Louis	Missouri	United States	63131
456	Siteman Cancer Center at Christian Hospital	Saint Louis	Missouri	United States	63136
457	Mercy Hospital Saint Louis	Saint Louis	Missouri	United States	63141
458	Siteman Cancer Center at Saint Peters Hospital	Saint Peters	Missouri	United States	63376
459	Sainte Genevieve County Memorial Hospital	Sainte Genevieve	Missouri	United States	63670
460	Mercy Hospital Springfield	Springfield	Missouri	United States	65804
461	CoxHealth South Hospital	Springfield	Missouri	United States	65807
462	Missouri Baptist Sullivan Hospital	Sullivan	Missouri	United States	63080
463	Missouri Baptist Outpatient Center-Sunset Hills	Sunset Hills	Missouri	United States	63127
464	Mercy Hospital Washington	Washington	Missouri	United States	63090
465	Community Hospital of Anaconda	Anaconda	Montana	United States	59711
466	Billings Clinic Cancer Center	Billings	Montana	United States	59101
467	Saint Vincent Healthcare	Billings	Montana	United States	59101
468	Saint Vincent Frontier Cancer Center	Billings	Montana	United States	59102
469	Bozeman Deaconess Hospital	Bozeman	Montana	United States	59715
470	Saint James Community Hospital and Cancer Treatment Center	Butte	Montana	United States	59701
471	Benefis Healthcare- Sletten Cancer Institute	Great Falls	Montana	United States	59405
472	Great Falls Clinic	Great Falls	Montana	United States	59405
473	Saint Peter's Community Hospital	Helena	Montana	United States	59601
474	Kalispell Regional Medical Center	Kalispell	Montana	United States	59901
475	Saint Patrick Hospital - Community Hospital	Missoula	Montana	United States	59802
476	Community Medical Hospital	Missoula	Montana	United States	59804
477	Nebraska Medicine-Bellevue	Bellevue	Nebraska	United States	68123
478	CHI Health Saint Francis	Grand Island	Nebraska	United States	68803
479	Heartland Hematology and Oncology	Kearney	Nebraska	United States	68845
480	CHI Health Good Samaritan	Kearney	Nebraska	United States	68847
481	Saint Elizabeth Regional Medical Center	Lincoln	Nebraska	United States	68510
482	Nebraska Medicine-Village Pointe	Omaha	Nebraska	United States	68118
483	Alegent Health Immanuel Medical Center	Omaha	Nebraska	United States	68122
484	Hematology and Oncology Consultants PC	Omaha	Nebraska	United States	68122
485	Alegent Health Bergan Mercy Medical Center	Omaha	Nebraska	United States	68124
486	Alegent Health Lakeside Hospital	Omaha	Nebraska	United States	68130
487	Creighton University Medical Center	Omaha	Nebraska	United States	68131
488	University of Nebraska Medical Center	Omaha	Nebraska	United States	68198
489	Midlands Community Hospital	Papillion	Nebraska	United States	68046
490	Dartmouth Hitchcock Medical Center	Lebanon	New Hampshire	United States	03756
491	Norris Cotton Cancer Center-Manchester	Manchester	New Hampshire	United States	03102
492	Norris Cotton Cancer Center-Nashua	Nashua	New Hampshire	United States	03063
493	Cooper Hospital University Medical Center	Camden	New Jersey	United States	08103
494	AtlantiCare Health Park-Cape May Court House	Cape May Court House	New Jersey	United States	08210
495	AtlantiCare Surgery Center	Egg Harbor Township	New Jersey	United States	08234
496	Newark Beth Israel Medical Center	Newark	New Jersey	United States	07112
497	Overlook Hospital	Summit	New Jersey	United States	07902
498	Holy Name Hospital	Teaneck	New Jersey	United States	07666
499	MD Anderson Cancer Center at Cooper-Voorhees	Voorhees	New Jersey	United States	08043
500	Lovelace Medical Center-Downtown	Albuquerque	New Mexico	United States	87102
501	Lovelace Medical Center-Saint Joseph Square	Albuquerque	New Mexico	United States	87102
502	University of New Mexico Cancer Center	Albuquerque	New Mexico	United States	87102
503	New Mexico Oncology Hematology Consultants	Albuquerque	New Mexico	United States	87109
504	Presbyterian Kaseman Hospital	Albuquerque	New Mexico	United States	87110
505	Memorial Medical Center - Las Cruces	Las Cruces	New Mexico	United States	88011
506	Presbyterian Rust Medical Center/Jorgensen Cancer Center	Rio Rancho	New Mexico	United States	87124
507	Christus Saint Vincent Regional Cancer Center	Santa Fe	New Mexico	United States	87505
508	Roswell Park Cancer Institute	Buffalo	New York	United States	14263
509	NYU Winthrop Hospital	Mineola	New York	United States	11501
510	State University of New York Upstate Medical University	Syracuse	New York	United States	13210
511	SUNY Upstate Medical Center-Community Campus	Syracuse	New York	United States	13215
512	Dickstein Cancer Treatment Center	White Plains	New York	United States	10601
513	AdventHealth Infusion Center Asheville	Asheville	North Carolina	United States	28803
514	UNC Lineberger Comprehensive Cancer Center	Chapel Hill	North Carolina	United States	27599
515	Southeastern Medical Oncology Center-Clinton	Clinton	North Carolina	United States	28328
516	AdventHealth Infusion Center Haywood	Clyde	North Carolina	United States	28721
517	Southeastern Medical Oncology Center-Goldsboro	Goldsboro	North Carolina	United States	27534
518	Wayne Memorial Hospital	Goldsboro	North Carolina	United States	27534
519	Hendersonville Hematology and Oncology at Pardee	Hendersonville	North Carolina	United States	28791
520	Margaret R Pardee Memorial Hospital	Hendersonville	North Carolina	United States	28791
521	AdventHealth Hendersonville	Hendersonville	North Carolina	United States	28792
522	Onslow Memorial Hospital	Jacksonville	North Carolina	United States	28546
523	Southeastern Medical Oncology Center-Jacksonville	Jacksonville	North Carolina	United States	28546
524	Vidant Oncology-Kenansville	Kenansville	North Carolina	United States	28349
525	Vidant Oncology-Kinston	Kinston	North Carolina	United States	28501
526	FirstHealth of the Carolinas-Moore Regional Hospital	Pinehurst	North Carolina	United States	28374
527	Vidant Oncology-Richlands	Richlands	North Carolina	United States	28574
528	Sanford Bismarck Medical Center	Bismarck	North Dakota	United States	58501
529	Essentia Health Cancer Center-South University Clinic	Fargo	North Dakota	United States	58103
530	Sanford South University Medical Center	Fargo	North Dakota	United States	58103
531	Sanford Broadway Medical Center	Fargo	North Dakota	United States	58122
532	Sanford Roger Maris Cancer Center	Fargo	North Dakota	United States	58122
533	Essentia Health - Jamestown Clinic	Jamestown	North Dakota	United States	58401
534	Trinity Cancer Care Center	Minot	North Dakota	United States	58701
535	Summa Health System - Akron Campus	Akron	Ohio	United States	44304
536	Cleveland Clinic Akron General	Akron	Ohio	United States	44307
537	Indu and Raj Soin Medical Center	Beavercreek	Ohio	United States	45431
538	Strecker Cancer Center-Belpre	Belpre	Ohio	United States	45714
539	Saint Elizabeth Boardman Hospital	Boardman	Ohio	United States	44512
540	Cleveland Clinic Mercy Hospital	Canton	Ohio	United States	44708
541	Dayton Physicians LLC-Miami Valley South	Centerville	Ohio	United States	45459
542	Miami Valley Hospital South	Centerville	Ohio	United States	45459
543	Adena Regional Medical Center	Chillicothe	Ohio	United States	45601
544	Oncology Hematology Care Inc-Eden Park	Cincinnati	Ohio	United States	45202
545	Oncology Hematology Care Inc-Mercy West	Cincinnati	Ohio	United States	45211
546	University of Cincinnati Cancer Center-UC Medical Center	Cincinnati	Ohio	United States	45219
547	Good Samaritan Hospital - Cincinnati	Cincinnati	Ohio	United States	45220
548	Oncology Hematology Care Inc-Anderson	Cincinnati	Ohio	United States	45230
549	Oncology Hematology Care Inc-Kenwood	Cincinnati	Ohio	United States	45236
550	Bethesda North Hospital	Cincinnati	Ohio	United States	45242
551	Oncology Hematology Care Inc-Blue Ash	Cincinnati	Ohio	United States	45242
552	TriHealth Cancer Institute-Westside	Cincinnati	Ohio	United States	45247
553	TriHealth Cancer Institute-Anderson	Cincinnati	Ohio	United States	45255
554	Cleveland Clinic Cancer Center/Fairview Hospital	Cleveland	Ohio	United States	44111
555	Cleveland Clinic Foundation	Cleveland	Ohio	United States	44195
556	Mount Carmel East Hospital	Columbus	Ohio	United States	43213
557	Columbus Oncology and Hematology Associates Inc	Columbus	Ohio	United States	43214
558	Riverside Methodist Hospital	Columbus	Ohio	United States	43214
559	Grant Medical Center	Columbus	Ohio	United States	43215
560	The Mark H Zangmeister Center	Columbus	Ohio	United States	43219
561	Mount Carmel Health Center West	Columbus	Ohio	United States	43222
562	Doctors Hospital	Columbus	Ohio	United States	43228
563	Good Samaritan Hospital - Dayton	Dayton	Ohio	United States	45406
564	Miami Valley Hospital	Dayton	Ohio	United States	45409
565	Dayton Physician LLC-Miami Valley Hospital North	Dayton	Ohio	United States	45415
566	Miami Valley Hospital North	Dayton	Ohio	United States	45415
567	Delaware Health Center-Grady Cancer Center	Delaware	Ohio	United States	43015
568	Delaware Radiation Oncology	Delaware	Ohio	United States	43015
569	Grady Memorial Hospital	Delaware	Ohio	United States	43015
570	Dublin Methodist Hospital	Dublin	Ohio	United States	43016
571	Oncology Hematology Care Inc-Healthplex	Fairfield	Ohio	United States	45014
572	Armes Family Cancer Center	Findlay	Ohio	United States	45840
573	Blanchard Valley Hospital	Findlay	Ohio	United States	45840
574	Orion Cancer Care	Findlay	Ohio	United States	45840
575	Atrium Medical Center-Middletown Regional Hospital	Franklin	Ohio	United States	45005-1066
576	Dayton Physicians LLC-Atrium	Franklin	Ohio	United States	45005
577	Dayton Physicians LLC-Wayne	Greenville	Ohio	United States	45331
578	Wayne Hospital	Greenville	Ohio	United States	45331
579	Cleveland Clinic Cancer Center Independence	Independence	Ohio	United States	44131
580	Greater Dayton Cancer Center	Kettering	Ohio	United States	45409
581	First Dayton Cancer Care	Kettering	Ohio	United States	45420
582	Kettering Medical Center	Kettering	Ohio	United States	45429
583	Fairfield Medical Center	Lancaster	Ohio	United States	43130
584	Saint Rita's Medical Center	Lima	Ohio	United States	45801
585	OhioHealth Mansfield Hospital	Mansfield	Ohio	United States	44903
586	Cleveland Clinic Cancer Center Mansfield	Mansfield	Ohio	United States	44906
587	Marietta Memorial Hospital	Marietta	Ohio	United States	45750
588	OhioHealth Marion General Hospital	Marion	Ohio	United States	43302
589	Toledo Clinic Cancer Centers-Maumee	Maumee	Ohio	United States	43537
590	Toledo Radiation Oncology at Northwest Ohio Onocolgy Center	Maumee	Ohio	United States	43537
591	Hillcrest Hospital Cancer Center	Mayfield Heights	Ohio	United States	44124
592	Dayton Physicians LLC-Signal Point	Middletown	Ohio	United States	45042
593	Knox Community Hospital	Mount Vernon	Ohio	United States	43050
594	Licking Memorial Hospital	Newark	Ohio	United States	43055
595	Newark Radiation Oncology	Newark	Ohio	United States	43055
596	Saint Charles Hospital	Oregon	Ohio	United States	43616
597	Mercy Health Perrysburg Cancer Center	Perrysburg	Ohio	United States	43551
598	Southern Ohio Medical Center	Portsmouth	Ohio	United States	45662
599	North Coast Cancer Care	Sandusky	Ohio	United States	44870
600	Dayton Physicians LLC-Wilson	Sidney	Ohio	United States	45365
601	Springfield Regional Cancer Center	Springfield	Ohio	United States	45504
602	Springfield Regional Medical Center	Springfield	Ohio	United States	45505
603	Trinity's Tony Teramana Cancer Center	Steubenville	Ohio	United States	43952
604	Cleveland Clinic Cancer Center Strongsville	Strongsville	Ohio	United States	44136
605	ProMedica Flower Hospital	Sylvania	Ohio	United States	43560
606	ProMedica Toledo Hospital/Russell J Ebeid Children's Hospital	Toledo	Ohio	United States	43606
607	Mercy Health - Saint Anne Hospital	Toledo	Ohio	United States	43623
608	Toledo Clinic Cancer Centers-Toledo	Toledo	Ohio	United States	43623
609	Dayton Physicians LLC-Upper Valley	Troy	Ohio	United States	45373
610	Upper Valley Medical Center	Troy	Ohio	United States	45373
611	South Pointe Hospital	Warrensville Heights	Ohio	United States	44122
612	Saint Joseph Warren Hospital	Warren	Ohio	United States	44484
613	University of Cincinnati Cancer Center-West Chester	West Chester	Ohio	United States	45069
614	Saint Ann's Hospital	Westerville	Ohio	United States	43081
615	Cleveland Clinic Wooster Family Health and Surgery Center	Wooster	Ohio	United States	44691
616	Saint Elizabeth Youngstown Hospital	Youngstown	Ohio	United States	44501
617	Genesis Healthcare System Cancer Care Center	Zanesville	Ohio	United States	43701
618	Cancer Centers of Southwest Oklahoma Research	Lawton	Oklahoma	United States	73505
619	University of Oklahoma Health Sciences Center	Oklahoma City	Oklahoma	United States	73104
620	Integris Southwest Medical Center	Oklahoma City	Oklahoma	United States	73109
621	Mercy Hospital Oklahoma City	Oklahoma City	Oklahoma	United States	73120
622	Integris Cancer Institute of Oklahoma	Oklahoma City	Oklahoma	United States	73142
623	Oklahoma Cancer Specialists and Research Institute-Tulsa	Tulsa	Oklahoma	United States	74146
624	Saint Alphonsus Medical Center-Baker City	Baker City	Oregon	United States	97814
625	Saint Charles Health System	Bend	Oregon	United States	97701
626	Clackamas Radiation Oncology Center	Clackamas	Oregon	United States	97015
627	Providence Cancer Institute Clackamas Clinic	Clackamas	Oregon	United States	97015
628	Bay Area Hospital	Coos Bay	Oregon	United States	97420
629	Legacy Mount Hood Medical Center	Gresham	Oregon	United States	97030
630	Providence Newberg Medical Center	Newberg	Oregon	United States	97132
631	Saint Alphonsus Medical Center-Ontario	Ontario	Oregon	United States	97914
632	Providence Willamette Falls Medical Center	Oregon City	Oregon	United States	97045
633	Legacy Good Samaritan Hospital and Medical Center	Portland	Oregon	United States	97210
634	Providence Portland Medical Center	Portland	Oregon	United States	97213
635	Providence Saint Vincent Medical Center	Portland	Oregon	United States	97225
636	Saint Charles Health System-Redmond	Redmond	Oregon	United States	97756
637	Legacy Meridian Park Hospital	Tualatin	Oregon	United States	97062
638	Jefferson Abington Hospital	Abington	Pennsylvania	United States	19001
639	Lehigh Valley Hospital-Cedar Crest	Allentown	Pennsylvania	United States	18103
640	UPMC-Heritage Valley Health System Beaver	Beaver	Pennsylvania	United States	15009
641	Lehigh Valley Hospital - Muhlenberg	Bethlehem	Pennsylvania	United States	18017
642	Crozer-Keystone Regional Cancer Center at Broomall	Broomall	Pennsylvania	United States	19008
643	Bryn Mawr Hospital	Bryn Mawr	Pennsylvania	United States	19010
644	Christiana Care Health System-Concord Health Center	Chadds Ford	Pennsylvania	United States	19317
645	Geisinger Medical Center	Danville	Pennsylvania	United States	17822
646	Doylestown Hospital	Doylestown	Pennsylvania	United States	18901
647	UPMC Hillman Cancer Center Erie	Erie	Pennsylvania	United States	16505
648	Crozer Regional Cancer Center at Brinton Lake	Glen Mills	Pennsylvania	United States	19342
649	UPMC Cancer Centers - Arnold Palmer Pavilion	Greensburg	Pennsylvania	United States	15601
650	UPMC Pinnacle Harrisburg	Harrisburg	Pennsylvania	United States	17101
651	UPMC Pinnacle Cancer Center/Community Osteopathic Campus	Harrisburg	Pennsylvania	United States	17109
652	Geisinger Medical Center-Cancer Center Hazleton	Hazleton	Pennsylvania	United States	18201
653	UPMC-Johnstown/John P. Murtha Regional Cancer Center	Johnstown	Pennsylvania	United States	15901
654	Geisinger Medical Oncology-Lewisburg	Lewisburg	Pennsylvania	United States	17837
655	Lewistown Hospital	Lewistown	Pennsylvania	United States	17044
656	UPMC Cancer Center at UPMC McKeesport	McKeesport	Pennsylvania	United States	15132
657	Riddle Memorial Hospital	Media	Pennsylvania	United States	19063
658	UPMC-Coraopolis/Heritage Valley Radiation Oncology	Moon	Pennsylvania	United States	15108
659	Consultants in Medical Oncology and Hematology?Newtown Square	Newtown Square	Pennsylvania	United States	19073
660	Paoli Memorial Hospital	Paoli	Pennsylvania	United States	19301
661	Thomas Jefferson University Hospital	Philadelphia	Pennsylvania	United States	19107
662	Fox Chase Cancer Center	Philadelphia	Pennsylvania	United States	19111
663	UPMC-Magee Womens Hospital	Pittsburgh	Pennsylvania	United States	15213
664	UPMC-Presbyterian Hospital	Pittsburgh	Pennsylvania	United States	15213
665	UPMC-Saint Margaret	Pittsburgh	Pennsylvania	United States	15215
666	University of Pittsburgh Cancer Institute (UPCI)	Pittsburgh	Pennsylvania	United States	15232
667	UPMC-Shadyside Hospital	Pittsburgh	Pennsylvania	United States	15232
668	UPMC Jefferson Regional Radiation Oncology	Pittsburgh	Pennsylvania	United States	15236
669	UPMC-Passavant Hospital	Pittsburgh	Pennsylvania	United States	15237
670	UPMC-Saint Clair Hospital Cancer Center	Pittsburgh	Pennsylvania	United States	15243
671	Geisinger Cancer Services-Pottsville	Pottsville	Pennsylvania	United States	17901
672	Guthrie Medical Group PC-Robert Packer Hospital	Sayre	Pennsylvania	United States	18840
673	Community Medical Center	Scranton	Pennsylvania	United States	18510
674	Geisinger Medical Oncology-Selinsgrove	Selinsgrove	Pennsylvania	United States	17870
675	UPMC Cancer Center at UPMC Northwest	Seneca	Pennsylvania	United States	16346
676	Geisinger Medical Group	State College	Pennsylvania	United States	16801
677	UPMC Uniontown Hospital Radiation Oncology	Uniontown	Pennsylvania	United States	15401
678	UPMC Washington Hospital Radiation Oncology	Washington	Pennsylvania	United States	15301
679	Geisinger Wyoming Valley/Henry Cancer Center	Wilkes-Barre	Pennsylvania	United States	18711
680	UPMC Susquehanna	Williamsport	Pennsylvania	United States	17701
681	Lankenau Medical Center	Wynnewood	Pennsylvania	United States	19096
682	AnMed Health Cancer Center	Anderson	South Carolina	United States	29621
683	Prisma Health Cancer Institute - Spartanburg	Boiling Springs	South Carolina	United States	29316
684	Medical University of South Carolina	Charleston	South Carolina	United States	29425
685	Prisma Health Cancer Institute - Laurens	Clinton	South Carolina	United States	29325
686	Prisma Health Cancer Institute - Easley	Easley	South Carolina	United States	29640
687	McLeod Regional Medical Center	Florence	South Carolina	United States	29506
688	Saint Francis Hospital	Greenville	South Carolina	United States	29601
689	Prisma Health Cancer Institute - Butternut	Greenville	South Carolina	United States	29605
690	Prisma Health Cancer Institute - Faris	Greenville	South Carolina	United States	29605
691	Prisma Health Greenville Memorial Hospital	Greenville	South Carolina	United States	29605
692	Saint Francis Cancer Center	Greenville	South Carolina	United States	29607
693	Prisma Health Cancer Institute - Eastside	Greenville	South Carolina	United States	29615
694	Prisma Health Cancer Institute - Greer	Greer	South Carolina	United States	29650
695	Prisma Health Cancer Institute - Seneca	Seneca	South Carolina	United States	29672
696	Sanford Cancer Center Oncology Clinic	Sioux Falls	South Dakota	United States	57104
697	Sanford USD Medical Center - Sioux Falls	Sioux Falls	South Dakota	United States	57117-5134
698	Memorial Hospital	Chattanooga	Tennessee	United States	37404
699	Pulmonary Medicine Center of Chattanooga-Hixson	Hixson	Tennessee	United States	37343
700	Baptist Memorial Hospital and Cancer Center-Memphis	Memphis	Tennessee	United States	38120
701	Baptist Memorial Hospital for Women	Memphis	Tennessee	United States	38120
702	Family Cancer Center-Memphis	Memphis	Tennessee	United States	38120
703	Meharry Medical College	Nashville	Tennessee	United States	37208
704	Memorial GYN Plus	Ooltewah	Tennessee	United States	37363
705	The Don and Sybil Harrington Cancer Center	Amarillo	Texas	United States	79106
706	Dell Seton Medical Center at The University of Texas	Austin	Texas	United States	78701
707	Saint Joseph Regional Cancer Center	Bryan	Texas	United States	77802
708	Brooke Army Medical Center	Fort Sam Houston	Texas	United States	78234
709	University of Texas Medical Branch	Galveston	Texas	United States	77555-0565
710	UTMB Cancer Center at Victory Lakes	League City	Texas	United States	77573
711	Farmington Health Center	Farmington	Utah	United States	84025
712	Huntsman Cancer Institute/University of Utah	Salt Lake City	Utah	United States	84112
713	South Jordan Health Center	South Jordan	Utah	United States	84009
714	Norris Cotton Cancer Center-North	Saint Johnsbury	Vermont	United States	05819
715	Danville Regional Medical Center	Danville	Virginia	United States	24541
716	Providence Regional Cancer System-Aberdeen	Aberdeen	Washington	United States	98520
717	Cancer Care Center at Island Hospital	Anacortes	Washington	United States	98221
718	PeaceHealth Saint Joseph Medical Center	Bellingham	Washington	United States	98225
719	Harrison HealthPartners Hematology and Oncology-Bremerton	Bremerton	Washington	United States	98310
720	Harrison Medical Center	Bremerton	Washington	United States	98310
721	Highline Medical Center-Main Campus	Burien	Washington	United States	98166
722	Providence Regional Cancer System-Centralia	Centralia	Washington	United States	98531
723	Swedish Cancer Institute-Edmonds	Edmonds	Washington	United States	98026
724	Saint Elizabeth Hospital	Enumclaw	Washington	United States	98022
725	Providence Regional Cancer Partnership	Everett	Washington	United States	98201
726	Saint Francis Hospital	Federal Way	Washington	United States	98003
727	Swedish Cancer Institute-Issaquah	Issaquah	Washington	United States	98029
728	Kadlec Clinic Hematology and Oncology	Kennewick	Washington	United States	99336
729	Seattle Cancer Care Alliance at EvergreenHealth	Kirkland	Washington	United States	98034
730	Providence Regional Cancer System-Lacey	Lacey	Washington	United States	98503
731	Saint Clare Hospital	Lakewood	Washington	United States	98499
732	PeaceHealth Saint John Medical Center	Longview	Washington	United States	98632
733	Skagit Regional Health Cancer Care Center	Mount Vernon	Washington	United States	98274
734	Skagit Valley Hospital	Mount Vernon	Washington	United States	98274
735	Harrison HealthPartners Hematology and Oncology-Poulsbo	Poulsbo	Washington	United States	98370
736	Pacific Gynecology Specialists	Seattle	Washington	United States	98104
737	Swedish Medical Center-Ballard Campus	Seattle	Washington	United States	98107
738	Fred Hutchinson Cancer Research Center	Seattle	Washington	United States	98109
739	Seattle Cancer Care Alliance	Seattle	Washington	United States	98109
740	Kaiser Permanente Washington	Seattle	Washington	United States	98112
741	Swedish Medical Center-First Hill	Seattle	Washington	United States	98122-4307
742	Swedish Medical Center-Cherry Hill	Seattle	Washington	United States	98122-5711
743	University of Washington Medical Center - Montlake	Seattle	Washington	United States	98195
744	PeaceHealth United General Medical Center	Sedro-Woolley	Washington	United States	98284
745	Providence Regional Cancer System-Shelton	Shelton	Washington	United States	98584
746	MultiCare Deaconess Cancer and Blood Specialty Center - Valley	Spokane Valley	Washington	United States	99216
747	MultiCare Deaconess Cancer and Blood Specialty Center - Downtown	Spokane	Washington	United States	99204
748	MultiCare Deaconess Cancer and Blood Specialty Center - North	Spokane	Washington	United States	99218
749	Franciscan Research Center-Northwest Medical Plaza	Tacoma	Washington	United States	98405
750	Northwest Medical Specialties PLLC	Tacoma	Washington	United States	98405
751	PeaceHealth Southwest Medical Center	Vancouver	Washington	United States	98664
752	Legacy Cancer Institute Medical Oncology and Day Treatment	Vancouver	Washington	United States	98684
753	Legacy Salmon Creek Hospital	Vancouver	Washington	United States	98686
754	Providence Saint Mary Regional Cancer Center	Walla Walla	Washington	United States	99362
755	Wenatchee Valley Hospital and Clinics	Wenatchee	Washington	United States	98801
756	Providence Regional Cancer System-Yelm	Yelm	Washington	United States	98597
757	West Virginia University Charleston Division	Charleston	West Virginia	United States	25304
758	Edwards Comprehensive Cancer Center	Huntington	West Virginia	United States	25701
759	Duluth Clinic Ashland	Ashland	Wisconsin	United States	54806
760	Northwest Wisconsin Cancer Center	Ashland	Wisconsin	United States	54806
761	Aurora Cancer Care-Southern Lakes VLCC	Burlington	Wisconsin	United States	53105
762	Marshfield Clinic-Chippewa Center	Chippewa Falls	Wisconsin	United States	54729
763	Marshfield Clinic Cancer Center at Sacred Heart	Eau Claire	Wisconsin	United States	54701
764	Marshfield Medical Center-EC Cancer Center	Eau Claire	Wisconsin	United States	54701
765	Mayo Clinic Health System-Eau Claire Clinic	Eau Claire	Wisconsin	United States	54701
766	Aurora Health Center-Fond du Lac	Fond Du Lac	Wisconsin	United States	54937
767	Aurora Health Care Germantown Health Center	Germantown	Wisconsin	United States	53022
768	Aurora Cancer Care-Grafton	Grafton	Wisconsin	United States	53024
769	Green Bay Oncology at Saint Vincent Hospital	Green Bay	Wisconsin	United States	54301-3526
770	Saint Vincent Hospital Cancer Center Green Bay	Green Bay	Wisconsin	United States	54301
771	Saint Vincent Hospital Cancer Center at Saint Mary's	Green Bay	Wisconsin	United States	54303
772	Aurora BayCare Medical Center	Green Bay	Wisconsin	United States	54311
773	Aurora Cancer Care-Kenosha South	Kenosha	Wisconsin	United States	53142
774	Gundersen Lutheran Medical Center	La Crosse	Wisconsin	United States	54601
775	Mayo Clinic Health System-Franciscan Healthcare	La Crosse	Wisconsin	United States	54601
776	Marshfield Clinic - Ladysmith Center	Ladysmith	Wisconsin	United States	54848
777	Holy Family Memorial Hospital	Manitowoc	Wisconsin	United States	54221
778	Aurora Bay Area Medical Group-Marinette	Marinette	Wisconsin	United States	54143
779	Saint Vincent Hospital Cancer Center at Marinette	Marinette	Wisconsin	United States	54143
780	Marshfield Medical Center-Marshfield	Marshfield	Wisconsin	United States	54449
781	Aurora Cancer Care-Milwaukee	Milwaukee	Wisconsin	United States	53209
782	Aurora Saint Luke's Medical Center	Milwaukee	Wisconsin	United States	53215
783	Aurora Sinai Medical Center	Milwaukee	Wisconsin	United States	53233
784	Marshfield Clinic-Minocqua Center	Minocqua	Wisconsin	United States	54548
785	Cancer Center of Western Wisconsin	New Richmond	Wisconsin	United States	54017
786	Saint Vincent Hospital Cancer Center at Oconto Falls	Oconto Falls	Wisconsin	United States	54154
787	Vince Lombardi Cancer Clinic - Oshkosh	Oshkosh	Wisconsin	United States	54904
788	Aurora Cancer Care-Racine	Racine	Wisconsin	United States	53406
789	Marshfield Medical Center-Rice Lake	Rice Lake	Wisconsin	United States	54868
790	HSHS Saint Nicholas Hospital	Sheboygan	Wisconsin	United States	53081
791	Vince Lombardi Cancer Clinic-Sheboygan	Sheboygan	Wisconsin	United States	53081
792	Marshfield Medical Center-River Region at Stevens Point	Stevens Point	Wisconsin	United States	54482
793	Saint Vincent Hospital Cancer Center at Sturgeon Bay	Sturgeon Bay	Wisconsin	United States	54235-1495
794	Aurora Medical Center in Summit	Summit	Wisconsin	United States	53066
795	Vince Lombardi Cancer Clinic-Two Rivers	Two Rivers	Wisconsin	United States	54241
796	Marshfield Clinic-Wausau Center	Wausau	Wisconsin	United States	54401
797	Aurora Cancer Care-Milwaukee West	Wauwatosa	Wisconsin	United States	53226
798	Aurora West Allis Medical Center	West Allis	Wisconsin	United States	53227
799	Marshfield Medical Center - Weston	Weston	Wisconsin	United States	54476
800	Marshfield Clinic - Wisconsin Rapids Center	Wisconsin Rapids	Wisconsin	United States	54494
801	Cheyenne Regional Medical Center-West	Cheyenne	Wyoming	United States	82001
802	Big Horn Basin Cancer Center	Cody	Wyoming	United States	82414
803	Billings Clinic-Cody	Cody	Wyoming	United States	82414
804	Welch Cancer Center	Sheridan	Wyoming	United States	82801
805	Advance Oncology Center	Aguadilla		Puerto Rico	00603
806	Doctor's Cancer Center-Arecibo	Arecibo		Puerto Rico	00614
807	Cancer Center-Metro Medical Center Bayamon	Bayamon		Puerto Rico	00959-5060
808	Hematologia Oncologia San Pablo	Bayamon		Puerto Rico	00961
809	HIMA San Pablo Oncologic Hospital	Caguas		Puerto Rico	00726
810	Doctors Cancer Center	Manati		Puerto Rico	00674
811	Instituto Oncologia Moderna Ponce	Ponce		Puerto Rico	00716
812	San Juan Community Oncology Group	San Juan		Puerto Rico	00917
813	Primary Care Physician Group	San Juan		Puerto Rico	00920
814	Centro Comprensivo de Cancer de UPR	San Juan		Puerto Rico	00927
815	San Juan City Hospital	San Juan		Puerto Rico	00936
816	Centro de Hematologia y Oncologia del Sur	Santa Isabel		Puerto Rico	00757

Sponsors and Collaborators

• National Cancer Institute (NCI)

Investigators

• Principal Investigator: Eve T Rodler, Southwest Oncology Group

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

• Responsible Party: National Cancer Institute (NCI)
• ClinicalTrials.gov Identifier: NCT02595905
• Other Study ID Numbers: NCI-2015-01912; NCI-2015-01912; S1416; S1416; S1416; U10CA180888
• First Posted: Nov 4, 2015
• Last Update Posted: Aug 8, 2022
• Last Verified: Jun 1, 2022

• Additional relevant MeSH terms: Carcinoma; Breast Neoplasms; Brain Neoplasms; Neoplasms; Cisplatin; Veliparib

Study Results

No Results Posted as of Aug 8, 2022