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The Headache Inducing Effects of Cilostazol on Migraine Patients

Sponsor
Danish Headache Center (Other)
Overall Status
Completed
CT.gov ID
NCT01841827
Collaborator
(none)
14
Enrollment
1
Location
2
Arms
2
Duration (Months)
7
Patients Per Site Per Month

Study Details

Study Description

Brief Summary

We will use Cilostazol as a tool to investigate its headache inducing effects in migraine patients.

Condition or Disease Intervention/Treatment Phase
N/A

Study Design

Study Type:
Interventional
Actual Enrollment :
14 participants
Allocation:
Randomized
Intervention Model:
Crossover Assignment
Masking:
Double (Participant, Investigator)
Primary Purpose:
Health Services Research
Official Title:
The Headache Inducing Effects of Cilostazol on Migraine Patients
Study Start Date :
Apr 1, 2013
Actual Primary Completion Date :
Jun 1, 2013
Actual Study Completion Date :
Jun 1, 2013

Arms and Interventions

Arm Intervention/Treatment
Active Comparator: Cilostazol

Capsule of Cilostazol 200 mg are taken orally on each study day

Drug: Cilostazol
Other Names:
  • Pletal

    		•
    Placebo Comparator: Placebo

    A capsule of placebo containing starch are taken orally on each study day.

    Drug: Placebo

    Outcome Measures

    Primary Outcome Measures

    1. The incidens of headache or migraine after adminstration of Cilostazol in migraine patients compared to placebo. [Outcome measure will be done within 3 month. Final data will be presented within 6 months]

      Rectruitment of 14 patients will be done during April and May. Experiments will be carried out in May and June. Each experiment day takes 1½ hour. Data analysis will be done in June and July. Final data will be presented within 6 months.

    Eligibility Criteria

    Criteria

    Ages Eligible for Study:
    18 Years to 60 Years
    Sexes Eligible for Study:
    All
    Accepts Healthy Volunteers:
    No
    Inclusion Criteria:

    • Diagnosed with migraine without aura according to the IHS criteria from 2004.

    • Healthy besides migraine

    Exclusion Criteria:

    • Tension-type headache more than 3 days per month

    • Other types of primary headaches

    • Pregnancy

    • History of vascular diseases or psychiatric diseases.

    Contacts and Locations

    Locations

    Site City State Country Postal Code
    1 Danish Headache Center & Department of Neurology Copenhagen Glostrup Denmark 2600

    Sponsors and Collaborators

    • Danish Headache Center

    Investigators

    None specified.

    Study Documents (Full-Text)

    None provided.

    More Information

    Publications

    None provided.
    Responsible Party:
    Song Guo, MD, Danish Headache Center
    ClinicalTrials.gov Identifier:
    NCT01841827
    Other Study ID Numbers:
    • H-2-2013-033
    First Posted:
    Apr 29, 2013
    Last Update Posted:
    Jun 6, 2014
    Last Verified:
    Jun 1, 2014
    Additional relevant MeSH terms:
    Migraine Disorders
    Headache
    Cilostazol

    Study Results

    No Results Posted as of Jun 6, 2014