Home-Based Dual-Task Training for Older Adults

• Sponsor: State University of New York at Buffalo (Other)
• Overall Status: Recruiting
• CT.gov ID: NCT05108246
• Collaborator: (none)
• Enrollment: 30
• Location: 1
• Arms: 2
• Anticipated Duration (Months): 11.2
• Patients Per Site Per Month: 2.7

Study Details

Study Description

Brief Summary

This project is focused on conducting a home-based, thinking while moving exercise intervention for adults 65 years or older, who have mild cognitive impairment, that will integrate several effective training modalities including non-contact cardio-kickboxing, stepping exercise, balance/functional training, and muscle strengthening. Cognitive function, physical function, and dual-task abilities will be assessed over the 12-week intervention and comparisons will be made between participants in the exercise intervention and control participants receiving no intervention.

Condition or Disease	Intervention/Treatment	Phase
Mild Cognitive Impairment	Behavioral: Dual-Task Exercise Training	N/A

Study Design

• Study Type: Interventional
• Anticipated Enrollment: 30 participants
• Allocation: Randomized
• Intervention Model: Parallel Assignment
• Masking: None (Open Label)
• Primary Purpose: Treatment
• Official Title: Home-Based Dual-Task Training to Improve Function in Older Adults
• Actual Study Start Date: Jan 25, 2022
• Anticipated Primary Completion Date: Oct 28, 2022
• Anticipated Study Completion Date: Dec 31, 2022

Arms and Interventions

Arm	Intervention/Treatment
Experimental: Dual-Task Training	Behavioral: Dual-Task Exercise Training; Simultaneous cognitive-motor training
No Intervention: Control

Outcome Measures

Primary Outcome Measures

1. Change in Cognitive Function (Interference inhibition and attention) [baseline, 6 week, 12 weeks]

   Change in performance on the Stroop Color-Word Interference Test

2. Change in Cognitive Function (Task-switching and attention) [baseline, 6 week, 12 weeks]

   Change in performance on the Trail-Making Test Sections A and B

3. Change in Walking Ability, Lower-Body Strength, and Balance [baseline, 6 weeks, 12 weeks]

   Change in performance on the Short Physical Performance Battery

Secondary Outcome Measures

1. Change in Dual-Task Performance [baseline, 6 week, 12 weeks]

   Change in the Timed Up and Go Test: Dual Task (single condition, motor condition, and cognitive condition

Eligibility Criteria

Criteria

• Ages Eligible for Study: 65 Years and Older
• Sexes Eligible for Study: All
• Accepts Healthy Volunteers: No

Inclusion Criteria:

• 65 years or older

• Male or female

• Screened positive for mild cognitive impairment (Montreal Cognitive Assessment score 23 to 26 points

• Having no absolute contraindications to non-physician supervised exercise.

Exclusion Criteria:

• Lower-body amputation

• Non-English language speaker

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	University at Buffalo, SUNY	Buffalo	New York	United States	14203

Sponsors and Collaborators

• State University of New York at Buffalo

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

• Responsible Party: Nikhil Satchidanand, Principal Investigator, State University of New York at Buffalo
• ClinicalTrials.gov Identifier: NCT05108246
• Other Study ID Numbers: STUDY00004857
• First Posted: Nov 4, 2021
• Last Update Posted: Apr 1, 2022
• Last Verified: Mar 1, 2022

• Individual Participant Data (IPD) Sharing Statement: No
• Plan to Share IPD: No
• Studies a U.S. FDA-regulated Drug Product: No
• Studies a U.S. FDA-regulated Device Product: No
• Additional relevant MeSH terms: Cognitive Dysfunction

Study Results

No Results Posted as of Apr 1, 2022