A Study of miRNA 371 in Patients With Germ Cell Tumors
Sponsor
Southwest Oncology Group (Other)
Overall Status
Recruiting
CT.gov ID
NCT04435756
Collaborator
National Cancer Institute (NCI) (NIH)
956
377
64
2.5
0
Study Details
Study Description
Brief Summary
This trial studies whether the blood marker micro ribonucleic acid (miRNA) 371 can predict the chance of cancer returning in patients with germ cell cancers. Studying samples of blood from patients with germ cell cancers in the laboratory may help doctors predict how likely the cancer will come back.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
Detailed Description
PRIMARY OBJECTIVE:
- To estimate the positive predictive value within each of the early stage testicular seminoma and nonseminoma groups using plasma miRNA 371 expression at relapse to detect germ cell malignancy.
SECONDARY OBJECTIVES:
-
To bank prospectively obtained serial liquid biospecimens for low and moderate risk of relapse patients annotated by patient level clinical data.
-
To bank prospectively collected, clinically annotated specimens for high risk patients and non-testicular primary patients in collaboration with Children's Oncology Group study AGCT 1531.
OUTLINE:
Patients undergo collection of blood every 3-6 months for up to 3 years.
Study Design
Study Type:
Observational
Anticipated Enrollment
:
956 participants
Observational Model:
Cohort
Time Perspective:
Prospective
Official Title:
A Prospective Observational Cohort Study to Assess miRNA 371 for Outcome Prediction in Patients With Newly Diagnosed Germ Cell Tumors
Actual Study Start Date
:
Jun 1, 2020
Anticipated Primary Completion Date
:
Oct 1, 2025
Anticipated Study Completion Date
:
Oct 1, 2025
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| Observational (blood collection) Patients undergo collection of blood every 3-6 months for up to 3 years. |
Other: Biomarker Analysis
Correlative study
Procedure: Blood Product Collection
Undergo collection of blood
Other Names:
|
Outcome Measures
Primary Outcome Measures
- To estimate positive predictive value of miRNA 371 in early stage testicular seminoma and nonseminoma patients [Up to 3 years]
Positive predictive value will be estimated using plasma miRNA 371 expression at relapse.
- To bank blood specimens of patients at low risk and moderate risk of relapse [Up to 3 years]
10 ml whole blood will be collected at time points specified by the protocol.
Eligibility Criteria
Criteria
Ages Eligible for Study:
18 Years
and Older
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
No
Inclusion Criteria:
-
Patients must have a new diagnosis of a germ cell tumor. confirmed pathologically or serologically (diagnostic elevation of human chorionic gonadotropin [HCG]/alpha-fetoprotein [AFP]). All primary sites, stages, histological subtypes of germ cell tumor are eligible. Metachronous second primary germ cell tumors are eligible
-
If surgery is planned, male patients with clinical stage I testicular cancer must have orchiectomy completed within 42 days prior to registration
-
Patients must be registered within 42 days after diagnosis and prior to initiation of a management plan or treatment for the disease
-
Patients must have initial imaging, laboratory and other clinical evaluations (see below) performed within 42 days prior to registration. Imaging reports, pathology reports and performance status will be collected
-
Patients must have beta-human chorionic gonadotropin (beta- HCG), alpha-fetoprotein (AFP), and lactate dehydrogenase (LDH) assessments within 42 days prior to registration
-
NOTE: If the patient had an orchiectomy prior to registration, report tumor marker values before and after surgery on the Baseline Tumor Marker form
-
Patients must have risk of relapse assessment determined by the local investigator prior to registration
-
Patients must agree to submit required specimens for defined translational medicine studies. These specimens are drawn at the same time as standard laboratory evaluations (beta-HCG, AFP, and LDH); NOTE: Ideally, patients should be willing to return to their center performing surveillance (registering site) for the duration of the study to ensure that specimens are timed to standard clinical observations (the registering site's surveillance schedule)
-
Patients must be offered participation in specimen banking for future research. With patient's consent, specimens must be submitted.
-
Patients must be informed of the investigational nature of this study and must sign and give written informed consent in accordance with institutional and federal guidelines
-
As a part of the Oncology Patient Enrollment Network (OPEN) registration process the treating institution's identity is provided in order to ensure that the current (within 365 days) date of institutional review board approval for this study has been entered in the system
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | Banner MD Anderson Cancer Center | Gilbert | Arizona | United States | 85234 |
| 2 | Kingman Regional Medical Center | Kingman | Arizona | United States | 86401 |
| 3 | University of Arizona Cancer Center-Orange Grove Campus | Tucson | Arizona | United States | 85704 |
| 4 | Banner University Medical Center - Tucson | Tucson | Arizona | United States | 85719 |
| 5 | University of Arizona Cancer Center-North Campus | Tucson | Arizona | United States | 85719 |
| 6 | Mercy Hospital Fort Smith | Fort Smith | Arkansas | United States | 72903 |
| 7 | Kaiser Permanente-Anaheim | Anaheim | California | United States | 92806 |
| 8 | Kaiser Permanente-Deer Valley Medical Center | Antioch | California | United States | 94531 |
| 9 | PCR Oncology | Arroyo Grande | California | United States | 93420 |
| 10 | Kaiser Permanente-Baldwin Park | Baldwin Park | California | United States | 91706 |
| 11 | Kaiser Permanente-Bellflower | Bellflower | California | United States | 90706 |
| 12 | Epic Care-Dublin | Dublin | California | United States | 94568 |
| 13 | Kaiser Permanente Dublin | Dublin | California | United States | 94568 |
| 14 | Bay Area Breast Surgeons Inc | Emeryville | California | United States | 94608 |
| 15 | Epic Care Partners in Cancer Care | Emeryville | California | United States | 94608 |
| 16 | Kaiser Permanente-Fontana | Fontana | California | United States | 92335 |
| 17 | Kaiser Permanente-Fremont | Fremont | California | United States | 94538 |
| 18 | Fresno Cancer Center | Fresno | California | United States | 93720 |
| 19 | Kaiser Permanente-Fresno | Fresno | California | United States | 93720 |
| 20 | Kaiser Permanente - Harbor City | Harbor City | California | United States | 90710 |
| 21 | Kaiser Permanente-Irvine | Irvine | California | United States | 92618 |
| 22 | UC San Diego Moores Cancer Center | La Jolla | California | United States | 92093 |
| 23 | Loma Linda University Medical Center | Loma Linda | California | United States | 92354 |
| 24 | Kaiser Permanente Los Angeles Medical Center | Los Angeles | California | United States | 90027 |
| 25 | Los Angeles County-USC Medical Center | Los Angeles | California | United States | 90033 |
| 26 | USC / Norris Comprehensive Cancer Center | Los Angeles | California | United States | 90033 |
| 27 | Kaiser Permanente West Los Angeles | Los Angeles | California | United States | 90034 |
| 28 | UCLA / Jonsson Comprehensive Cancer Center | Los Angeles | California | United States | 90095 |
| 29 | Contra Costa Regional Medical Center | Martinez | California | United States | 94553-3156 |
| 30 | Kaiser Permanente-Modesto | Modesto | California | United States | 95356 |
| 31 | UCI Health Newport -- Birch Street | Newport Beach | California | United States | 92660 |
| 32 | USC Norris Oncology/Hematology-Newport Beach | Newport Beach | California | United States | 92663 |
| 33 | Alta Bates Summit Medical Center - Summit Campus | Oakland | California | United States | 94609 |
| 34 | Bay Area Tumor Institute | Oakland | California | United States | 94609 |
| 35 | Kaiser Permanente Oakland-Broadway | Oakland | California | United States | 94611 |
| 36 | Kaiser Permanente-Oakland | Oakland | California | United States | 94611 |
| 37 | Kaiser Permanente-Ontario | Ontario | California | United States | 91761 |
| 38 | UC Irvine Health/Chao Family Comprehensive Cancer Center | Orange | California | United States | 92868 |
| 39 | Kaiser Permanente - Panorama City | Panorama City | California | United States | 91402 |
| 40 | Keck Medical Center of USC Pasadena | Pasadena | California | United States | 91105 |
| 41 | Kaiser Permanente-Rancho Cordova Cancer Center | Rancho Cordova | California | United States | 95670 |
| 42 | Kaiser Permanente- Marshall Medical Offices | Redwood City | California | United States | 94063 |
| 43 | Kaiser Permanente-Redwood City | Redwood City | California | United States | 94063 |
| 44 | Kaiser Permanente-Richmond | Richmond | California | United States | 94801 |
| 45 | Kaiser Permanente-Riverside | Riverside | California | United States | 92505 |
| 46 | Rohnert Park Cancer Center | Rohnert Park | California | United States | 94928 |
| 47 | Kaiser Permanente-Roseville | Roseville | California | United States | 95661 |
| 48 | The Permanente Medical Group-Roseville Radiation Oncology | Roseville | California | United States | 95678 |
| 49 | Kaiser Permanente Downtown Commons | Sacramento | California | United States | 95814 |
| 50 | Kaiser Permanente-South Sacramento | Sacramento | California | United States | 95823 |
| 51 | South Sacramento Cancer Center | Sacramento | California | United States | 95823 |
| 52 | Kaiser Permanente-San Diego Mission | San Diego | California | United States | 92108 |
| 53 | Kaiser Permanente-San Diego Zion | San Diego | California | United States | 92120 |
| 54 | Kaiser Permanente-San Francisco | San Francisco | California | United States | 94115 |
| 55 | Kaiser Permanente-Santa Teresa-San Jose | San Jose | California | United States | 95119 |
| 56 | Kaiser Permanente San Leandro | San Leandro | California | United States | 94577 |
| 57 | Kaiser Permanente-San Marcos | San Marcos | California | United States | 92078 |
| 58 | Kaiser San Rafael-Gallinas | San Rafael | California | United States | 94903 |
| 59 | Kaiser Permanente Medical Center - Santa Clara | Santa Clara | California | United States | 95051 |
| 60 | Kaiser Permanente-Santa Rosa | Santa Rosa | California | United States | 95403 |
| 61 | Kaiser Permanente Cancer Treatment Center | South San Francisco | California | United States | 94080 |
| 62 | Kaiser Permanente-South San Francisco | South San Francisco | California | United States | 94080 |
| 63 | Kaiser Permanente-Stockton | Stockton | California | United States | 95210 |
| 64 | Kaiser Permanente Medical Center-Vacaville | Vacaville | California | United States | 95688 |
| 65 | Kaiser Permanente-Vallejo | Vallejo | California | United States | 94589 |
| 66 | Kaiser Permanente-Walnut Creek | Walnut Creek | California | United States | 94596 |
| 67 | Epic Care Cyberknife Center | Walnut Creek | California | United States | 94597 |
| 68 | Kaiser Permanente-Woodland Hills | Woodland Hills | California | United States | 91367 |
| 69 | University of Colorado Hospital | Aurora | Colorado | United States | 80045 |
| 70 | Poudre Valley Hospital | Fort Collins | Colorado | United States | 80524 |
| 71 | Cancer Care and Hematology-Fort Collins | Fort Collins | Colorado | United States | 80528 |
| 72 | UCHealth Greeley Hospital | Greeley | Colorado | United States | 80631 |
| 73 | UCHealth Highlands Ranch Hospital | Highlands Ranch | Colorado | United States | 80129 |
| 74 | Medical Center of the Rockies | Loveland | Colorado | United States | 80538 |
| 75 | Hawaii Cancer Care - Savio | 'Aiea | Hawaii | United States | 96701 |
| 76 | Pali Momi Medical Center | 'Aiea | Hawaii | United States | 96701 |
| 77 | Queen's Cancer Center - Pearlridge | 'Aiea | Hawaii | United States | 96701 |
| 78 | The Cancer Center of Hawaii-Pali Momi | 'Aiea | Hawaii | United States | 96701 |
| 79 | The Queen's Medical Center - West Oahu | 'Ewa Beach | Hawaii | United States | 96706 |
| 80 | Hawaii Cancer Care Inc - Waterfront Plaza | Honolulu | Hawaii | United States | 96813 |
| 81 | Island Urology | Honolulu | Hawaii | United States | 96813 |
| 82 | Queen's Cancer Cenrer - POB I | Honolulu | Hawaii | United States | 96813 |
| 83 | Queen's Medical Center | Honolulu | Hawaii | United States | 96813 |
| 84 | Straub Clinic and Hospital | Honolulu | Hawaii | United States | 96813 |
| 85 | University of Hawaii Cancer Center | Honolulu | Hawaii | United States | 96813 |
| 86 | Hawaii Cancer Care Inc-Liliha | Honolulu | Hawaii | United States | 96817 |
| 87 | Hawaii Diagnostic Radiology Services LLC | Honolulu | Hawaii | United States | 96817 |
| 88 | Kuakini Medical Center | Honolulu | Hawaii | United States | 96817 |
| 89 | Queen's Cancer Center - Kuakini | Honolulu | Hawaii | United States | 96817 |
| 90 | The Cancer Center of Hawaii-Liliha | Honolulu | Hawaii | United States | 96817 |
| 91 | Kaiser Permanente Moanalua Medical Center | Honolulu | Hawaii | United States | 96819 |
| 92 | Kapiolani Medical Center for Women and Children | Honolulu | Hawaii | United States | 96826 |
| 93 | Straub Medical Center - Kahului Clinic | Kahului | Hawaii | United States | 96732 |
| 94 | Castle Medical Center | Kailua | Hawaii | United States | 96734 |
| 95 | Wilcox Memorial Hospital and Kauai Medical Clinic | Lihue | Hawaii | United States | 96766 |
| 96 | Saint Anthony's Health | Alton | Illinois | United States | 62002 |
| 97 | Rush - Copley Medical Center | Aurora | Illinois | United States | 60504 |
| 98 | Illinois CancerCare-Bloomington | Bloomington | Illinois | United States | 61704 |
| 99 | Illinois CancerCare-Canton | Canton | Illinois | United States | 61520 |
| 100 | Memorial Hospital of Carbondale | Carbondale | Illinois | United States | 62902 |
| 101 | SIH Cancer Institute | Carterville | Illinois | United States | 62918 |
| 102 | Illinois CancerCare-Carthage | Carthage | Illinois | United States | 62321 |
| 103 | Centralia Oncology Clinic | Centralia | Illinois | United States | 62801 |
| 104 | Northwestern University | Chicago | Illinois | United States | 60611 |
| 105 | University of Chicago Comprehensive Cancer Center | Chicago | Illinois | United States | 60637 |
| 106 | Carle on Vermilion | Danville | Illinois | United States | 61832 |
| 107 | Cancer Care Specialists of Illinois - Decatur | Decatur | Illinois | United States | 62526 |
| 108 | Decatur Memorial Hospital | Decatur | Illinois | United States | 62526 |
| 109 | Illinois CancerCare-Dixon | Dixon | Illinois | United States | 61021 |
| 110 | Carle Physician Group-Effingham | Effingham | Illinois | United States | 62401 |
| 111 | Crossroads Cancer Center | Effingham | Illinois | United States | 62401 |
| 112 | Illinois CancerCare-Galesburg | Galesburg | Illinois | United States | 61401 |
| 113 | Western Illinois Cancer Treatment Center | Galesburg | Illinois | United States | 61401 |
| 114 | Ingalls Memorial Hospital | Harvey | Illinois | United States | 60426 |
| 115 | Illinois CancerCare-Kewanee Clinic | Kewanee | Illinois | United States | 61443 |
| 116 | Illinois CancerCare-Macomb | Macomb | Illinois | United States | 61455 |
| 117 | Carle Physician Group-Mattoon/Charleston | Mattoon | Illinois | United States | 61938 |
| 118 | Good Samaritan Regional Health Center | Mount Vernon | Illinois | United States | 62864 |
| 119 | UC Comprehensive Cancer Center at Silver Cross | New Lenox | Illinois | United States | 60451 |
| 120 | Cancer Care Center of O'Fallon | O'Fallon | Illinois | United States | 62269 |
| 121 | University of Chicago Medicine-Orland Park | Orland Park | Illinois | United States | 60462 |
| 122 | Illinois CancerCare-Ottawa Clinic | Ottawa | Illinois | United States | 61350 |
| 123 | Illinois CancerCare-Pekin | Pekin | Illinois | United States | 61554 |
| 124 | Illinois CancerCare-Peoria | Peoria | Illinois | United States | 61615 |
| 125 | Methodist Medical Center of Illinois | Peoria | Illinois | United States | 61636 |
| 126 | Illinois CancerCare-Peru | Peru | Illinois | United States | 61354 |
| 127 | Valley Radiation Oncology | Peru | Illinois | United States | 61354 |
| 128 | Illinois CancerCare-Princeton | Princeton | Illinois | United States | 61356 |
| 129 | Southern Illinois University School of Medicine | Springfield | Illinois | United States | 62702 |
| 130 | Springfield Clinic | Springfield | Illinois | United States | 62702 |
| 131 | Memorial Medical Center | Springfield | Illinois | United States | 62781 |
| 132 | Southwest Illinois Health Services LLP | Swansea | Illinois | United States | 62226 |
| 133 | Carle Cancer Center | Urbana | Illinois | United States | 61801 |
| 134 | The Carle Foundation Hospital | Urbana | Illinois | United States | 61801 |
| 135 | Illinois CancerCare - Washington | Washington | Illinois | United States | 61571 |
| 136 | Rush-Copley Healthcare Center | Yorkville | Illinois | United States | 60560 |
| 137 | Indiana University/Melvin and Bren Simon Cancer Center | Indianapolis | Indiana | United States | 46202 |
| 138 | University of Iowa Healthcare Cancer Services Quad Cities | Bettendorf | Iowa | United States | 52722 |
| 139 | Saint Anthony Regional Hospital | Carroll | Iowa | United States | 51401 |
| 140 | Iowa Methodist Medical Center | Des Moines | Iowa | United States | 50309 |
| 141 | Medical Oncology and Hematology Associates-Des Moines | Des Moines | Iowa | United States | 50309 |
| 142 | Broadlawns Medical Center | Des Moines | Iowa | United States | 50314 |
| 143 | Iowa Lutheran Hospital | Des Moines | Iowa | United States | 50316 |
| 144 | Trinity Regional Medical Center | Fort Dodge | Iowa | United States | 50501 |
| 145 | University of Iowa/Holden Comprehensive Cancer Center | Iowa City | Iowa | United States | 52242 |
| 146 | Methodist West Hospital | West Des Moines | Iowa | United States | 50266-7700 |
| 147 | Central Care Cancer Center - Garden City | Garden City | Kansas | United States | 67846 |
| 148 | Central Care Cancer Center - Great Bend | Great Bend | Kansas | United States | 67530 |
| 149 | LSU Healthcare Network / Metairie Multi-Specialty Clinic | Metairie | Louisiana | United States | 70006 |
| 150 | Louisiana State University Health Science Center | New Orleans | Louisiana | United States | 70112 |
| 151 | Bronson Battle Creek | Battle Creek | Michigan | United States | 49017 |
| 152 | Helen DeVos Children's Hospital at Spectrum Health | Grand Rapids | Michigan | United States | 49503 |
| 153 | Mercy Health Saint Mary's | Grand Rapids | Michigan | United States | 49503 |
| 154 | Spectrum Health at Butterworth Campus | Grand Rapids | Michigan | United States | 49503 |
| 155 | Bronson Methodist Hospital | Kalamazoo | Michigan | United States | 49007 |
| 156 | West Michigan Cancer Center | Kalamazoo | Michigan | United States | 49007 |
| 157 | Ascension Borgess Cancer Center | Kalamazoo | Michigan | United States | 49009 |
| 158 | Borgess Medical Center | Kalamazoo | Michigan | United States | 49048 |
| 159 | Mercy Health Mercy Campus | Muskegon | Michigan | United States | 49444 |
| 160 | Lakeland Hospital Niles | Niles | Michigan | United States | 49120 |
| 161 | Cancer and Hematology Centers of Western Michigan - Norton Shores | Norton Shores | Michigan | United States | 49444 |
| 162 | Spectrum Health Reed City Hospital | Reed City | Michigan | United States | 49677 |
| 163 | Lakeland Medical Center Saint Joseph | Saint Joseph | Michigan | United States | 49085 |
| 164 | Marie Yeager Cancer Center | Saint Joseph | Michigan | United States | 49085 |
| 165 | Munson Medical Center | Traverse City | Michigan | United States | 49684 |
| 166 | Metro Health Hospital | Wyoming | Michigan | United States | 49519 |
| 167 | Riverwood Healthcare Center | Aitkin | Minnesota | United States | 56431 |
| 168 | Sanford Joe Lueken Cancer Center | Bemidji | Minnesota | United States | 56601 |
| 169 | Essentia Health Saint Joseph's Medical Center | Brainerd | Minnesota | United States | 56401 |
| 170 | Essentia Health - Deer River Clinic | Deer River | Minnesota | United States | 56636 |
| 171 | Essentia Health Saint Mary's - Detroit Lakes Clinic | Detroit Lakes | Minnesota | United States | 56501 |
| 172 | Essentia Health Cancer Center | Duluth | Minnesota | United States | 55805 |
| 173 | Essentia Health Saint Mary's Medical Center | Duluth | Minnesota | United States | 55805 |
| 174 | Miller-Dwan Hospital | Duluth | Minnesota | United States | 55805 |
| 175 | Lake Region Healthcare Corporation-Cancer Care | Fergus Falls | Minnesota | United States | 56537 |
| 176 | Essentia Health - Fosston | Fosston | Minnesota | United States | 56542 |
| 177 | Essentia Health Hibbing Clinic | Hibbing | Minnesota | United States | 55746 |
| 178 | Essentia Health - Park Rapids | Park Rapids | Minnesota | United States | 56470 |
| 179 | Essentia Health Sandstone | Sandstone | Minnesota | United States | 55072 |
| 180 | Sanford Thief River Falls Medical Center | Thief River Falls | Minnesota | United States | 56701 |
| 181 | Essentia Health Virginia Clinic | Virginia | Minnesota | United States | 55792 |
| 182 | Sanford Cancer Center Worthington | Worthington | Minnesota | United States | 56187 |
| 183 | University of Mississippi Medical Center | Jackson | Mississippi | United States | 39216 |
| 184 | Saint Louis Cancer and Breast Institute-Ballwin | Ballwin | Missouri | United States | 63011 |
| 185 | Central Care Cancer Center - Bolivar | Bolivar | Missouri | United States | 65613 |
| 186 | Cox Cancer Center Branson | Branson | Missouri | United States | 65616 |
| 187 | Saint Francis Medical Center | Cape Girardeau | Missouri | United States | 63703 |
| 188 | Southeast Cancer Center | Cape Girardeau | Missouri | United States | 63703 |
| 189 | Siteman Cancer Center at West County Hospital | Creve Coeur | Missouri | United States | 63141 |
| 190 | Parkland Health Center - Farmington | Farmington | Missouri | United States | 63640 |
| 191 | Capital Region Southwest Campus | Jefferson City | Missouri | United States | 65109 |
| 192 | Freeman Health System | Joplin | Missouri | United States | 64804 |
| 193 | Mercy Hospital Joplin | Joplin | Missouri | United States | 64804 |
| 194 | Delbert Day Cancer Institute at PCRMC | Rolla | Missouri | United States | 65401 |
| 195 | Mercy Clinic-Rolla-Cancer and Hematology | Rolla | Missouri | United States | 65401 |
| 196 | Heartland Regional Medical Center | Saint Joseph | Missouri | United States | 64506 |
| 197 | Saint Louis Cancer and Breast Institute-South City | Saint Louis | Missouri | United States | 63109 |
| 198 | Washington University School of Medicine | Saint Louis | Missouri | United States | 63110 |
| 199 | Mercy Hospital South | Saint Louis | Missouri | United States | 63128 |
| 200 | Siteman Cancer Center-South County | Saint Louis | Missouri | United States | 63129 |
| 201 | Missouri Baptist Medical Center | Saint Louis | Missouri | United States | 63131 |
| 202 | Siteman Cancer Center at Christian Hospital | Saint Louis | Missouri | United States | 63136 |
| 203 | Mercy Hospital Saint Louis | Saint Louis | Missouri | United States | 63141 |
| 204 | Siteman Cancer Center at Saint Peters Hospital | Saint Peters | Missouri | United States | 63376 |
| 205 | Sainte Genevieve County Memorial Hospital | Sainte Genevieve | Missouri | United States | 63670 |
| 206 | Mercy Hospital Springfield | Springfield | Missouri | United States | 65804 |
| 207 | CoxHealth South Hospital | Springfield | Missouri | United States | 65807 |
| 208 | Missouri Baptist Sullivan Hospital | Sullivan | Missouri | United States | 63080 |
| 209 | Missouri Baptist Outpatient Center-Sunset Hills | Sunset Hills | Missouri | United States | 63127 |
| 210 | Mercy Hospital Washington | Washington | Missouri | United States | 63090 |
| 211 | Nebraska Medicine-Bellevue | Bellevue | Nebraska | United States | 68123 |
| 212 | Nebraska Medicine-Village Pointe | Omaha | Nebraska | United States | 68118 |
| 213 | University of Nebraska Medical Center | Omaha | Nebraska | United States | 68198 |
| 214 | Carson Tahoe Regional Medical Center | Carson City | Nevada | United States | 89703 |
| 215 | Cancer and Blood Specialists-Henderson | Henderson | Nevada | United States | 89052 |
| 216 | Comprehensive Cancer Centers of Nevada - Henderson | Henderson | Nevada | United States | 89052 |
| 217 | Comprehensive Cancer Centers of Nevada-Horizon Ridge | Henderson | Nevada | United States | 89052 |
| 218 | Las Vegas Cancer Center-Henderson | Henderson | Nevada | United States | 89052 |
| 219 | OptumCare Cancer Care at Seven Hills | Henderson | Nevada | United States | 89052 |
| 220 | 21st Century Oncology-Henderson | Henderson | Nevada | United States | 89074 |
| 221 | Comprehensive Cancer Centers of Nevada-Southeast Henderson | Henderson | Nevada | United States | 89074 |
| 222 | Las Vegas Urology - Green Valley | Henderson | Nevada | United States | 89074 |
| 223 | Las Vegas Urology - Pebble | Henderson | Nevada | United States | 89074 |
| 224 | Urology Specialists of Nevada - Green Valley | Henderson | Nevada | United States | 89074 |
| 225 | Las Vegas Urology - Pecos | Las Vegas | Nevada | United States | 89074 |
| 226 | Desert West Surgery | Las Vegas | Nevada | United States | 89102 |
| 227 | OptumCare Cancer Care at Charleston | Las Vegas | Nevada | United States | 89102 |
| 228 | University Medical Center of Southern Nevada | Las Vegas | Nevada | United States | 89102 |
| 229 | Hope Cancer Care of Nevada | Las Vegas | Nevada | United States | 89103 |
| 230 | Radiation Oncology Centers of Nevada Central | Las Vegas | Nevada | United States | 89106 |
| 231 | Urology Specialists of Nevada - Central | Las Vegas | Nevada | United States | 89106 |
| 232 | 21st Century Oncology | Las Vegas | Nevada | United States | 89109 |
| 233 | Sunrise Hospital and Medical Center | Las Vegas | Nevada | United States | 89109 |
| 234 | Las Vegas Prostate Cancer Center | Las Vegas | Nevada | United States | 89113 |
| 235 | Las Vegas Urology - Sunset | Las Vegas | Nevada | United States | 89113 |
| 236 | Urology Specialists of Nevada - Southwest | Las Vegas | Nevada | United States | 89113 |
| 237 | Radiation Oncology Centers of Nevada Southeast | Las Vegas | Nevada | United States | 89119 |
| 238 | 21st Century Oncology-Vegas Tenaya | Las Vegas | Nevada | United States | 89128 |
| 239 | Ann M Wierman MD LTD | Las Vegas | Nevada | United States | 89128 |
| 240 | Comprehensive Cancer Centers of Nevada - Northwest | Las Vegas | Nevada | United States | 89128 |
| 241 | Las Vegas Urology - Cathedral Rock | Las Vegas | Nevada | United States | 89128 |
| 242 | Las Vegas Urology - Smoke Ranch | Las Vegas | Nevada | United States | 89128 |
| 243 | OptumCare Cancer Care at MountainView | Las Vegas | Nevada | United States | 89128 |
| 244 | Urology Specialists of Nevada - Northwest | Las Vegas | Nevada | United States | 89128 |
| 245 | Alliance for Childhood Diseases/Cure 4 the Kids Foundation | Las Vegas | Nevada | United States | 89135 |
| 246 | Comprehensive Cancer Centers of Nevada - Town Center | Las Vegas | Nevada | United States | 89144 |
| 247 | Comprehensive Cancer Centers of Nevada-Summerlin | Las Vegas | Nevada | United States | 89144 |
| 248 | Summerlin Hospital Medical Center | Las Vegas | Nevada | United States | 89144 |
| 249 | Las Vegas Cancer Center-Medical Center | Las Vegas | Nevada | United States | 89148-2405 |
| 250 | 21st Century Oncology-Fort Apache | Las Vegas | Nevada | United States | 89148 |
| 251 | Comprehensive Cancer Centers of Nevada | Las Vegas | Nevada | United States | 89148 |
| 252 | OptumCare Cancer Care at Fort Apache | Las Vegas | Nevada | United States | 89148 |
| 253 | Comprehensive Cancer Centers of Nevada - Central Valley | Las Vegas | Nevada | United States | 89169 |
| 254 | University Cancer Center | Las Vegas | Nevada | United States | 89169 |
| 255 | Hope Cancer Care of Nevada-Pahrump | Pahrump | Nevada | United States | 89048 |
| 256 | Renown Regional Medical Center | Reno | Nevada | United States | 89502 |
| 257 | Saint Mary's Regional Medical Center | Reno | Nevada | United States | 89503 |
| 258 | Radiation Oncology Associates | Reno | Nevada | United States | 89509 |
| 259 | Rutgers Cancer Institute of New Jersey | New Brunswick | New Jersey | United States | 08903 |
| 260 | University of New Mexico Cancer Center | Albuquerque | New Mexico | United States | 87102 |
| 261 | Northwell Health/Center for Advanced Medicine | Lake Success | New York | United States | 11042 |
| 262 | University of Rochester | Rochester | New York | United States | 14642 |
| 263 | Messino Cancer Centers | Asheville | North Carolina | United States | 28806 |
| 264 | Sanford Bismarck Medical Center | Bismarck | North Dakota | United States | 58501 |
| 265 | Essentia Health Cancer Center-South University Clinic | Fargo | North Dakota | United States | 58103 |
| 266 | Sanford South University Medical Center | Fargo | North Dakota | United States | 58103 |
| 267 | Southpointe-Sanford Medical Center Fargo | Fargo | North Dakota | United States | 58103 |
| 268 | Sanford Medical Center Fargo | Fargo | North Dakota | United States | 58104 |
| 269 | Sanford Broadway Medical Center | Fargo | North Dakota | United States | 58122 |
| 270 | Sanford Roger Maris Cancer Center | Fargo | North Dakota | United States | 58122 |
| 271 | Essentia Health - Jamestown Clinic | Jamestown | North Dakota | United States | 58401 |
| 272 | Strecker Cancer Center-Belpre | Belpre | Ohio | United States | 45714 |
| 273 | Adena Regional Medical Center | Chillicothe | Ohio | United States | 45601 |
| 274 | University of Cincinnati Cancer Center-UC Medical Center | Cincinnati | Ohio | United States | 45219 |
| 275 | Ohio State University Comprehensive Cancer Center | Columbus | Ohio | United States | 43210 |
| 276 | Mount Carmel East Hospital | Columbus | Ohio | United States | 43213 |
| 277 | Columbus Oncology and Hematology Associates Inc | Columbus | Ohio | United States | 43214 |
| 278 | Riverside Methodist Hospital | Columbus | Ohio | United States | 43214 |
| 279 | Grant Medical Center | Columbus | Ohio | United States | 43215 |
| 280 | The Mark H Zangmeister Center | Columbus | Ohio | United States | 43219 |
| 281 | Mount Carmel Health Center West | Columbus | Ohio | United States | 43222 |
| 282 | Doctors Hospital | Columbus | Ohio | United States | 43228 |
| 283 | Delaware Health Center-Grady Cancer Center | Delaware | Ohio | United States | 43015 |
| 284 | Grady Memorial Hospital | Delaware | Ohio | United States | 43015 |
| 285 | Dublin Methodist Hospital | Dublin | Ohio | United States | 43016 |
| 286 | Central Ohio Breast and Endocrine Surgery | Gahanna | Ohio | United States | 43230 |
| 287 | Mount Carmel Grove City Hospital | Grove City | Ohio | United States | 43123 |
| 288 | Fairfield Medical Center | Lancaster | Ohio | United States | 43130 |
| 289 | Saint Rita's Medical Center | Lima | Ohio | United States | 45801 |
| 290 | OhioHealth Mansfield Hospital | Mansfield | Ohio | United States | 44903 |
| 291 | Marietta Memorial Hospital | Marietta | Ohio | United States | 45750 |
| 292 | OhioHealth Marion General Hospital | Marion | Ohio | United States | 43302 |
| 293 | Knox Community Hospital | Mount Vernon | Ohio | United States | 43050 |
| 294 | Licking Memorial Hospital | Newark | Ohio | United States | 43055 |
| 295 | Newark Radiation Oncology | Newark | Ohio | United States | 43055 |
| 296 | Mercy Health Perrysburg Cancer Center | Perrysburg | Ohio | United States | 43551 |
| 297 | Southern Ohio Medical Center | Portsmouth | Ohio | United States | 45662 |
| 298 | Saint Vincent Mercy Medical Center | Toledo | Ohio | United States | 43608 |
| 299 | Mercy Health - Saint Anne Hospital | Toledo | Ohio | United States | 43623 |
| 300 | University of Cincinnati Cancer Center-West Chester | West Chester | Ohio | United States | 45069 |
| 301 | Saint Ann's Hospital | Westerville | Ohio | United States | 43081 |
| 302 | Genesis Healthcare System Cancer Care Center | Zanesville | Ohio | United States | 43701 |
| 303 | University of Oklahoma Health Sciences Center | Oklahoma City | Oklahoma | United States | 73104 |
| 304 | Mercy Hospital Oklahoma City | Oklahoma City | Oklahoma | United States | 73120 |
| 305 | Kaiser Permanente Northwest | Portland | Oregon | United States | 97227 |
| 306 | Oregon Health and Science University | Portland | Oregon | United States | 97239 |
| 307 | Salem Hospital | Salem | Oregon | United States | 97301 |
| 308 | University of Pennsylvania/Abramson Cancer Center | Philadelphia | Pennsylvania | United States | 19104 |
| 309 | Prisma Health Cancer Institute - Spartanburg | Boiling Springs | South Carolina | United States | 29316 |
| 310 | Prisma Health Cancer Institute - Easley | Easley | South Carolina | United States | 29640 |
| 311 | Prisma Health Cancer Institute - Butternut | Greenville | South Carolina | United States | 29605 |
| 312 | Prisma Health Cancer Institute - Faris | Greenville | South Carolina | United States | 29605 |
| 313 | Prisma Health Greenville Memorial Hospital | Greenville | South Carolina | United States | 29605 |
| 314 | Prisma Health Cancer Institute - Eastside | Greenville | South Carolina | United States | 29615 |
| 315 | Prisma Health Cancer Institute - Greer | Greer | South Carolina | United States | 29650 |
| 316 | Prisma Health Cancer Institute - Seneca | Seneca | South Carolina | United States | 29672 |
| 317 | Sanford Cancer Center Oncology Clinic | Sioux Falls | South Dakota | United States | 57104 |
| 318 | Sanford USD Medical Center - Sioux Falls | Sioux Falls | South Dakota | United States | 57117-5134 |
| 319 | Vanderbilt-Ingram Cancer Center Cool Springs | Franklin | Tennessee | United States | 37067 |
| 320 | Vanderbilt Breast Center at One Hundred Oaks | Nashville | Tennessee | United States | 37204 |
| 321 | Vanderbilt University/Ingram Cancer Center | Nashville | Tennessee | United States | 37232 |
| 322 | Parkland Memorial Hospital | Dallas | Texas | United States | 75235 |
| 323 | UT Southwestern/Simmons Cancer Center-Dallas | Dallas | Texas | United States | 75390 |
| 324 | Cancer Specialists of Tidewater Limited | Chesapeake | Virginia | United States | 23320 |
| 325 | Peninsula Cancer Institute-Gloucester | Gloucester | Virginia | United States | 23061 |
| 326 | Peninsula Cancer Institute-Newport News | Newport News | Virginia | United States | 23601 |
| 327 | VCU Massey Cancer Center at Stony Point | Richmond | Virginia | United States | 23235 |
| 328 | Virginia Commonwealth University/Massey Cancer Center | Richmond | Virginia | United States | 23298 |
| 329 | Cancer Specialists of Tidewater-Suffolk | Suffolk | Virginia | United States | 23435 |
| 330 | Peninsula Cancer Institute-Cancer Specialists of Tidewater | Virginia Beach | Virginia | United States | 23454 |
| 331 | Peninsula Cancer Institute-Williamsburg | Williamsburg | Virginia | United States | 23185 |
| 332 | Overlake Medical Center | Bellevue | Washington | United States | 98004 |
| 333 | Valley Medical Center | Renton | Washington | United States | 98055 |
| 334 | Virginia Mason Medical Center | Seattle | Washington | United States | 98101 |
| 335 | North Star Lodge Cancer Center at Yakima Valley Memorial Hospital | Yakima | Washington | United States | 98902 |
| 336 | Duluth Clinic Ashland | Ashland | Wisconsin | United States | 54806 |
| 337 | Northwest Wisconsin Cancer Center | Ashland | Wisconsin | United States | 54806 |
| 338 | Aurora Cancer Care-Southern Lakes VLCC | Burlington | Wisconsin | United States | 53105 |
| 339 | Marshfield Clinic-Chippewa Center | Chippewa Falls | Wisconsin | United States | 54729 |
| 340 | Aurora Saint Luke's South Shore | Cudahy | Wisconsin | United States | 53110 |
| 341 | Marshfield Medical Center-EC Cancer Center | Eau Claire | Wisconsin | United States | 54701 |
| 342 | Aurora Health Care Germantown Health Center | Germantown | Wisconsin | United States | 53022 |
| 343 | Aurora Cancer Care-Grafton | Grafton | Wisconsin | United States | 53024 |
| 344 | Saint Vincent Hospital Cancer Center Green Bay | Green Bay | Wisconsin | United States | 54301 |
| 345 | Saint Vincent Hospital Cancer Center at Saint Mary's | Green Bay | Wisconsin | United States | 54303 |
| 346 | Aurora BayCare Medical Center | Green Bay | Wisconsin | United States | 54311 |
| 347 | Aurora Cancer Care-Kenosha South | Kenosha | Wisconsin | United States | 53142 |
| 348 | Marshfield Clinic - Ladysmith Center | Ladysmith | Wisconsin | United States | 54848 |
| 349 | Aurora Bay Area Medical Group-Marinette | Marinette | Wisconsin | United States | 54143 |
| 350 | Marshfield Medical Center-Marshfield | Marshfield | Wisconsin | United States | 54449 |
| 351 | Aurora Cancer Care-Milwaukee | Milwaukee | Wisconsin | United States | 53209 |
| 352 | Aurora Saint Luke's Medical Center | Milwaukee | Wisconsin | United States | 53215 |
| 353 | Aurora Sinai Medical Center | Milwaukee | Wisconsin | United States | 53233 |
| 354 | Marshfield Clinic-Minocqua Center | Minocqua | Wisconsin | United States | 54548 |
| 355 | Saint Vincent Hospital Cancer Center at Oconto Falls | Oconto Falls | Wisconsin | United States | 54154 |
| 356 | Vince Lombardi Cancer Clinic - Oshkosh | Oshkosh | Wisconsin | United States | 54904 |
| 357 | Aurora Cancer Care-Racine | Racine | Wisconsin | United States | 53406 |
| 358 | Marshfield Medical Center-Rice Lake | Rice Lake | Wisconsin | United States | 54868 |
| 359 | Vince Lombardi Cancer Clinic-Sheboygan | Sheboygan | Wisconsin | United States | 53081 |
| 360 | Marshfield Clinic Stevens Point Center | Stevens Point | Wisconsin | United States | 54482 |
| 361 | Saint Vincent Hospital Cancer Center at Sturgeon Bay | Sturgeon Bay | Wisconsin | United States | 54235-1495 |
| 362 | Aurora Medical Center in Summit | Summit | Wisconsin | United States | 53066 |
| 363 | Vince Lombardi Cancer Clinic-Two Rivers | Two Rivers | Wisconsin | United States | 54241 |
| 364 | Marshfield Clinic-Wausau Center | Wausau | Wisconsin | United States | 54401 |
| 365 | Aurora Cancer Care-Milwaukee West | Wauwatosa | Wisconsin | United States | 53226 |
| 366 | Aurora West Allis Medical Center | West Allis | Wisconsin | United States | 53227 |
| 367 | Marshfield Medical Center - Weston | Weston | Wisconsin | United States | 54476 |
| 368 | Marshfield Clinic - Wisconsin Rapids Center | Wisconsin Rapids | Wisconsin | United States | 54494 |
| 369 | Cross Cancer Institute | Edmonton | Alberta | Canada | T6G 1Z2 |
| 370 | BCCA-Cancer Centre for the Southern Interior | Kelowna | British Columbia | Canada | V1Y 5L3 |
| 371 | BCCA-Vancouver Cancer Centre | Vancouver | British Columbia | Canada | V5Z 4E6 |
| 372 | BCCA-Vancouver Island Cancer Centre | Victoria | British Columbia | Canada | V8R 6V5 |
| 373 | QEII Health Sciences Centre/Nova Scotia Health Authority | Halifax | Nova Scotia | Canada | B3H 2Y9 |
| 374 | Cambridge Memorial Hospital | Cambridge | Ontario | Canada | N1R 3G2 |
| 375 | University Health Network-Princess Margaret Hospital | Toronto | Ontario | Canada | M5G 2M9 |
| 376 | Allan Blair Cancer Centre | Regina | Saskatchewan | Canada | S4T 7T1 |
| 377 | FHP Health Center-Guam | Tamuning | Guam | 96913 |
Sponsors and Collaborators
- Southwest Oncology Group
- National Cancer Institute (NCI)
Investigators
- Principal Investigator: Craig R Nichols, Southwest Oncology Group
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.Responsible Party:
Southwest Oncology Group
ClinicalTrials.gov Identifier:
NCT04435756
Other Study ID Numbers:
- S1823
- NCI-2019-06177
- S1823
- SWOG-S1823
- S1823
- UG1CA189974
First Posted:
Jun 17, 2020
Last Update Posted:
Mar 10, 2022
Last Verified:
Mar 1, 2022
Additional relevant MeSH terms: