GERICOVID: Mortality, Gravity Predictive Factors and Clinical Evolution of Older COVID-19 Patients in Short Geriatric Services.

Sponsor

Hospices Civils de Lyon (Other)

Overall Status

Active, not recruiting

CT.gov ID

NCT05455892

Collaborator

(none)

450

Enrollment

Locations

26.3

Anticipated Duration (Months)

Patients Per Site

3.4

Patients Per Site Per Month

Study Details

Study Description

Brief Summary

Since the beginning of the year 2020, clinical characteristics of a new disease as the global COVID-19 epidemic has spread in France. People over 70 years of age are the more concerned by this virus in proportion and in gravity with some atypical first symptoms compared to younger patients. Evolution of the disease is variable from forms with few symptoms to severe forms sometimes quickly lethal.

GERICOVID LYON is a descriptive analysis of all patients over 70 years of age hospitalised for COVID-19 in short geriatric unities of University Hospital of Lyon This study will allow more comprehension about COVID-19 in older people. The role of predictive factors, pre-existing comorbidities and the nature and frequency of complications in a short period will be investigate. Treatments practices will be analysed too.

Condition or Disease	Intervention/Treatment	Phase
COVID-19	Other: Clinical data collection during hospitalization in short geriatric units.

Study Design

Study Type:

Observational

Actual Enrollment :

450 participants

Observational Model:

Cohort

Time Perspective:

Retrospective

Official Title:

Analysis of Mortality, Gravity Predictive Factors and Evolution of Clinical Characteristics of Older Patients Hospitalized for COVID-19 in Short Geriatric Services.

Actual Study Start Date :

Jul 23, 2020

Actual Primary Completion Date :

Nov 1, 2021

Anticipated Study Completion Date :

Sep 30, 2022

Arms and Interventions

Arm	Intervention/Treatment
Elder patients hospitalized for COVID-19 in geriatric short stay units. All patients over 70 years of age, with a positive Polymerase Chain Reaction or a high presumption of COVID-19, hospitalized in short geriatric units in University Hospital of Lyon, who agree with retrospective collection of their clinical datas.	Other: Clinical data collection during hospitalization in short geriatric units. Retrospective clinical data collection, at time of infection and 10 days later. Correlation between mortality and gravity. Identification of predictive mortality factors such as frailty, preexisting comorbidities, complications and treatments. Description of medical prescription evolutions.

Arm

Intervention/Treatment

Elder patients hospitalized for COVID-19 in geriatric short stay units.

All patients over 70 years of age, with a positive Polymerase Chain Reaction or a high presumption of COVID-19, hospitalized in short geriatric units in University Hospital of Lyon, who agree with retrospective collection of their clinical datas.

Other: Clinical data collection during hospitalization in short geriatric units.

Retrospective clinical data collection, at time of infection and 10 days later. Correlation between mortality and gravity. Identification of predictive mortality factors such as frailty, preexisting comorbidities, complications and treatments. Description of medical prescription evolutions.

Outcome Measures

Primary Outcome Measures

In hospital mortality rate. [During patient hospitalization, an average of 10 days.]
Observed mortality rate will be presented with its 95% confidence interval.

Eligibility Criteria

Criteria

Ages Eligible for Study:

70 Years and Older

Sexes Eligible for Study:

All

Accepts Healthy Volunteers:

Inclusion Criteria:

Patient over 70 years of age.
Patient hospitalized in short geriatric units in University Hospital of Lyon.
Patient diagnosed with COVID-19 (positive Polymerase Chain Reaction or a high presumption of COVID-19 based on clinical and/or scannographic evidence).
Patient Informed and non-opposed to the research (Patient informed of the study by his medical doctor during hospitalization or by post, thanks to a generic information sheet dedicated to COVID-19 researches).

Exclusion Criteria:

Patient opposed to the research.

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	Service de gériatrie aigue de l'hôpital de la Croix Rousse. Hospices Civils de Lyon	Caluire-et-Cuire	Rhone	France	69300
2	Service de gériatrie aigue de l'hôpital Edouard Herriot, Pavillon T. Hospices Civils de Lyon	Lyon	Rhone	France	69003
3	Service de gériatrie aigue de l'hôpital Edouard Herriot. Hospices Civils de Lyon	Lyon	Rhone	France	69003
4	Service de gériatrie aigue de l'hôpital Lyon Sud. Hospices Civils de Lyon	Pierre-Bénite	Rhone	France	69495
5	Service de gériatrie aigue de l'hôpital des Charpennes. Hospices Civils de Lyon	Villeurbanne	Rhone	France	69100

Sponsors and Collaborators

Hospices Civils de Lyon

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

Responsible Party:

Hospices Civils de Lyon

ClinicalTrials.gov Identifier:

NCT05455892

Other Study ID Numbers:

AGORA n°36

First Posted:

Jul 13, 2022

Last Update Posted:

Jul 20, 2022

Last Verified:

Jul 1, 2022

Individual Participant Data (IPD) Sharing Statement:

Undecided

Plan to Share IPD:

Undecided

Studies a U.S. FDA-regulated Drug Product:

Studies a U.S. FDA-regulated Device Product:

Keywords provided by Hospices Civils de Lyon

ELDERLY

COVID-19

Additional relevant MeSH terms:

COVID-19

Study Results

No Results Posted as of Jul 20, 2022