Acute Effect of Resistance Exercise, Neuromuscular Electrical Stimulation, and Transcutaneous Electrical Stimulation Applications on Muscle Activation

Sponsor
Gazi University (Other)
Overall Status
Completed
CT.gov ID
NCT06016660
Collaborator
(none)
21
1
4
8
2.6

Study Details

Study Description

Brief Summary

The aim of our study is to investigate the effects of single-session resistance exercise, neuromuscular electrical stimulation, and transcutaneous electrical stimulation on the level of muscle activation and their superiority over each other on both the ipsilateral and contralateral sides. Our randomized controlled crossover study included 21 participants (13 female, 8 male, age; 27.7±4). Transcutaneous electrical stimulation was used for sensory input. A single-session application was performed only to the right extremities of all participants, and the acute effects on muscle activation on both the ipsilateral and contralateral sides were evaluated. Muscle activation was evaluated with superficial EMG. SPSS® Statistics V22.0 software was used for statistical analysis. As a result of the statistical analysis, a significant increase in activation was found only in the sensory input application group on the ipsilateral side flexor carpi radialis (FCR) (p=0.001), flexor carpi ulnaris (FCU) (p<0.001), flexor digitorum superficialis (FDS) (p=0.023) and flexor digitorum profundus (FDP) (p=0.003) muscles. On the contralateral side, there was an increase in activation in all muscles (FCR; p<0.001, FCU; p=0.033, FDS; p=0.017 and FDP; p=0.001) in the resistant exercise group. In addition, there was a significant increase in the activation of certain muscles on the contralateral side in the NMES application group (FCR (p=0.049) and FDP (p=0.016) muscles) and the sensory input application group (FDP (p=0.004) and FDS (p=0.043) muscles). In situations where movement is contraindicated, ipsilateral sensory input can increase the level of muscle activation through both cortical and peripheral neural mechanisms.In addition, resistance exercise to be performed on the contralateral side can be an effective application to increase muscle activation on the ipsilateral side.

Condition or Disease Intervention/Treatment Phase
  • Other: Physiotherapy
N/A

Study Design

Study Type:
Interventional
Actual Enrollment :
21 participants
Allocation:
Randomized
Intervention Model:
Crossover Assignment
Masking:
None (Open Label)
Primary Purpose:
Treatment
Official Title:
Acute Effect of Resistance Exercise, Neuromuscular Electrical Stimulation, and Transcutaneous Electrical Stimulation Applications on Muscle Activation
Actual Study Start Date :
May 1, 2022
Actual Primary Completion Date :
Oct 1, 2022
Actual Study Completion Date :
Jan 1, 2023

Arms and Interventions

Arm Intervention/Treatment
Experimental: Resistance exercise

Resistance exercise

Other: Physiotherapy
Resistance exercise, Neuromuscular electrical stimulation, and Transcutaneous electrical stimulation

Experimental: Neuromuscular electrical stimulation

Neuromuscular electrical stimulation

Other: Physiotherapy
Resistance exercise, Neuromuscular electrical stimulation, and Transcutaneous electrical stimulation

Experimental: Transcutaneous electrical stimulation

Transcutaneous electrical stimulation

Other: Physiotherapy
Resistance exercise, Neuromuscular electrical stimulation, and Transcutaneous electrical stimulation

No Intervention: Control

No intervention

Outcome Measures

Primary Outcome Measures

  1. Superficial electromyography [through study completion, an average of 1 year]

    Muscle activation measurement

Eligibility Criteria

Criteria

Ages Eligible for Study:
N/A and Older
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
Yes
Inclusion Criteria:

• After providing detailed information about the study, individuals who had agreed to participate in the research were included in the study.

Exclusion Criteria:
  • Individuals with any central or peripheral nervous system disease/injury affecting the upper extremity,

  • Individuals with a history of orthopedic injury that could impact the study,

  • Individuals with a history of neuromuscular disease, congenital anomalies, skin infections, or cognitive impairments,

  • Individuals with a history of systemic or metabolic diseases that could potentially affect the study,

  • Individuals with a body mass index (BMI) above 30 kg/m2.

Contacts and Locations

Locations

Site City State Country Postal Code
1 Barış SEVEN İzmir Çiğli Turkey

Sponsors and Collaborators

  • Gazi University

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.
Responsible Party:
Barış SEVEN, Ph.D. research assistant, Gazi University
ClinicalTrials.gov Identifier:
NCT06016660
Other Study ID Numbers:
  • EMGHealthy
First Posted:
Aug 30, 2023
Last Update Posted:
Aug 30, 2023
Last Verified:
Aug 1, 2023
Individual Participant Data (IPD) Sharing Statement:
No
Plan to Share IPD:
No
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No

Study Results

No Results Posted as of Aug 30, 2023