Vieillissement: Analysis of Motor Skills in the Elderly: the Role of Cognitive Abilities for Imagining and Planning Movement.

Sponsor
Centre Hospitalier Universitaire Dijon (Other)
Overall Status
Recruiting
CT.gov ID
NCT04754906
Collaborator
(none)
684
1
31.2
21.9

Study Details

Study Description

Brief Summary

Falling is an event that is more frequent and severe in older age. It can lead to a loss of autonomy and a decrease in quality of life. It is therefore important to understand this phenomenon in order to better prevent it. Among the multiple risk factors associated with falling, recent research has shown a link between the decline in cognitive abilities (i.e., the mental processes that form our knowledge, such as memory) and the risk of falling. However, the impact of this cognitive decline on motor skills is still poorly understood. The purpose of this research is to study how the changes induced by aging affect motor skills. This would make it possible to take a new look at the phenomenon of falls occurring in the elderly and, in the long term, to improve the prevention and rehabilitation.

Condition or Disease Intervention/Treatment Phase
  • Other: Sequence 1
  • Other: Sequence 2
  • Other: Sequence 3
  • Other: Sequence 4
  • Other: Sequence 5

Study Design

Study Type:
Observational
Anticipated Enrollment :
684 participants
Observational Model:
Case-Control
Time Perspective:
Prospective
Official Title:
Analysis of Motor Skills in the Elderly: the Role of Cognitive Abilities for Imagining and Planning Movement.
Actual Study Start Date :
Jan 25, 2021
Anticipated Primary Completion Date :
Sep 1, 2023
Anticipated Study Completion Date :
Sep 1, 2023

Arms and Interventions

Arm Intervention/Treatment
young neurotypical subjects

people from 18 to 40 years old

Other: Sequence 1
perform arm movements towards a target

Other: Sequence 2
judge the verticality of an object

Other: Sequence 3
In standing position, point as quickly as possible with the right arm at the diode that will light up in front of the participant.

Other: Sequence 4
Composed of 5 sessions of about 15 minutes each (5 consecutive days), it will be required to perform a walking test (10 meters) in 3 different conditions and a manual dexterity test. Participants will be asked to imagine carrying out these tests during the training sessions.

Other: Sequence 5
Composed of 5 sessions of about 20 minutes each (5 consecutive days), it will be asked to perform pointing movements of the arm. It will be asked to imagine these movements during training sessions.

elderly neurotypical subjects

people over 70 years of age

Other: Sequence 1
perform arm movements towards a target

Other: Sequence 2
judge the verticality of an object

Other: Sequence 3
In standing position, point as quickly as possible with the right arm at the diode that will light up in front of the participant.

Other: Sequence 4
Composed of 5 sessions of about 15 minutes each (5 consecutive days), it will be required to perform a walking test (10 meters) in 3 different conditions and a manual dexterity test. Participants will be asked to imagine carrying out these tests during the training sessions.

Other: Sequence 5
Composed of 5 sessions of about 20 minutes each (5 consecutive days), it will be asked to perform pointing movements of the arm. It will be asked to imagine these movements during training sessions.

Elderly subjects with mild cognitive impairment

people over 70 years of age, with a diagnosis of mild cognitive impairment

Other: Sequence 1
perform arm movements towards a target

Other: Sequence 2
judge the verticality of an object

Other: Sequence 3
In standing position, point as quickly as possible with the right arm at the diode that will light up in front of the participant.

Other: Sequence 4
Composed of 5 sessions of about 15 minutes each (5 consecutive days), it will be required to perform a walking test (10 meters) in 3 different conditions and a manual dexterity test. Participants will be asked to imagine carrying out these tests during the training sessions.

Other: Sequence 5
Composed of 5 sessions of about 20 minutes each (5 consecutive days), it will be asked to perform pointing movements of the arm. It will be asked to imagine these movements during training sessions.

Outcome Measures

Primary Outcome Measures

  1. Sequence 1: symmetry ratio of the finger speed profile [through study completion, an average of 3 years]

  2. Sequence 2 : perception bias (error in degrees of angle) of dynamic subjective visual vericality [through study completion, an average of 3 years]

  3. Sequence 3 : activation time of the focal muscles in relation to the postural muscles [through study completion, an average of 3 years]

  4. Sequence 4: temporal congruence between the duration of a movement realized and imagined [through study completion, an average of 3 years]

  5. Sequence 5: speed achieved after the mental training sessions [through study completion, an average of 3 years]

  6. Sequence 5: accuracy achieved after the mental training sessions [through study completion, an average of 3 years]

    speed-precision pointing test on a touch-sensitive tablet

Eligibility Criteria

Criteria

Ages Eligible for Study:
18 Years and Older
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
Yes
Inclusion Criteria:
  1. Neurotypical subjects group:
  • Person aged 18 to 40 years

  • Person who has given oral consent

  • Affiliated to national health insurance

  • Right-handed person

  1. Group of elderly neurotypical subjects:
  • Person over 70 years of age

  • Person who has given oral consent

  • Affiliated to national health insurance

  • No cognitive problems (MMSE score >26)

  • Right-handed person

  1. Elderly mild cognitive disorder subject group:
  • Person over 70 years of age

  • Person who has given oral consent

  • Diagnosis of Mild Cognitive Disorder made by a neurologist at the Centre Mémoire Ressources et Recherche (CMRR) of the University Hospital of Dijon, following the recommendations of the National Institute for Aging and Alzheimer's Association (Albert et al., 2011) This diagnosis is based on psychometric tests, brain imaging and the evolution of cognitive disorders, including an MMSE test.

  • Right-handed person

Exclusion Criteria:
  • Neurological or psychiatric history with the exception of the TCL group.

  • Follow-up of drug treatment in the last three months that may affect cognitive and/or motor skills.

  • Received a shoulder prosthesis on the dominant side.

  • Received a hip and/or knee replacement less than a year ago.

  • Disabling joint disease of the hip or knee shoulder

  • Protected adults (curatorship, guardianship)

  • Person deprived of their liberty b judicial or administrative decision

  • Pregnant, parturient or breastfeeding woman

  • Major unable to consent

Contacts and Locations

Locations

Site City State Country Postal Code
1 Chu Dijon Bourgogne Dijon France 21000

Sponsors and Collaborators

  • Centre Hospitalier Universitaire Dijon

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.
Responsible Party:
Centre Hospitalier Universitaire Dijon
ClinicalTrials.gov Identifier:
NCT04754906
Other Study ID Numbers:
  • MANCKOUNDIA 2018
First Posted:
Feb 15, 2021
Last Update Posted:
Feb 15, 2021
Last Verified:
Feb 1, 2021
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No
Additional relevant MeSH terms:

Study Results

No Results Posted as of Feb 15, 2021