MACAARET: Multicenter Retrospective Registry of Anterior Communicating Artery Aneurysms With Endovascular Therapy
Study Details
Study Description
Brief Summary
Based on the anatomical features of the anterior Communicating artery complex, the investigators will analyze the outcome of the ACoA aneurysms treated by endovascular therapy.
The most common site of intracranial aneurysms is the anterior communicating artery (AcomA). AcomA aneurysms account for approximately one-fourth of all intracranial aneurysms.
Recent publications have addressed specifically the endovascular treatment of AcoA aneurysms. Furthermore, detailed anatomic characteristics and the effects of the multiple variations of the anterior communicating artery complex have scarcely been reported.
The hemodynamic factors play a fundamental role in the adequate treatment of aneurismal coiling.
The objective of our registry is to analyze the impact of morphological configuration of the anterior communicating artery complex and the results of coil embolization in AcoA aneurysms
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
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Study Design
Outcome Measures
Primary Outcome Measures
- Effective Aneurysm Coiling (no residual cerebral aneurysm) [1 year]
Secondary Outcome Measures
- All Cause Mortality [1 year]
- Neurological Outcome (classified with the Glasgow Outcome Scale, Rankin Scale) [1 year]
All patients will be classified with the Glasgow Outcome Scale, Rankin Scale.
- Procedural device-related serious adverse events [1 year]
Eligibility Criteria
Criteria
Inclusion Criteria:
- Patient with Anterior Communicating Artery Aneurysm treated with endovascular coiling.
Exclusion Criteria:
- Patients without imaging follow up of at least 12 months after endovascular treatment.
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | Hospital Clinic | Barcelona | Spain | 08036 |
Sponsors and Collaborators
- Hospital Clinic of Barcelona
- Hospitales Universitarios Virgen del Rocío
- Hospital Universitario Reina Sofia de Cordoba
Investigators
- Principal Investigator: Federico Zarco, MD, Hospital Clinic of Barcelona
Study Documents (Full-Text)
None provided.More Information
Publications
- Birknes JK, Hwang SK, Pandey AS, Cockroft K, Dyer AM, Benitez RP, Veznedaroglu E, Rosenwasser RH. Feasibility and limitations of endovascular coil embolization of anterior communicating artery aneurysms: morphological considerations. Neurosurgery. 2006 Jul;59(1):43-52; discussion 43-52.
- Elias T, Ogungbo B, Connolly D, Gregson B, Mendelow AD, Gholkar A. Endovascular treatment of anterior communicating artery aneurysms: results of clinical and radiological outcome in Newcastle. Br J Neurosurg. 2003 Jun;17(3):278-86.
- Molyneux AJ, Kerr RS, Yu LM, Clarke M, Sneade M, Yarnold JA, Sandercock P; International Subarachnoid Aneurysm Trial (ISAT) Collaborative Group. International subarachnoid aneurysm trial (ISAT) of neurosurgical clipping versus endovascular coiling in 2143 patients with ruptured intracranial aneurysms: a randomised comparison of effects on survival, dependency, seizures, rebleeding, subgroups, and aneurysm occlusion. Lancet. 2005 Sep 3-9;366(9488):809-17.
- Moret J, Pierot L, Boulin A, Castaings L, Rey A. Endovascular treatment of anterior communicating artery aneurysms using Guglielmi detachable coils. Neuroradiology. 1996 Nov;38(8):800-5.
- NeurovascCDI001