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Multiphoton Laser Scanning Microscopy in Cutaneous Optical Pathology

Sponsor
National Taiwan University Hospital (Other)
Overall Status
Unknown status
CT.gov ID
NCT00508781
Collaborator
National Science Council, Taiwan (Other), National Health Research Institutes, Taiwan (Other)
400
Enrollment
1
Location
121
Duration (Months)
3.3
Patients Per Site Per Month

Study Details

Study Description

Brief Summary

We use multiphoton laser scanning microscopy to observe cutaneous anatomy and pathology. The study aims to compare surgical specimen by conventional pathology slice with the image by non-invasive multiphoton laser scanning microscopy.

Condition or Disease Intervention/Treatment Phase
  • Behavioral: Multiphoton laser image in cutaneous pathology

Detailed Description

For skin diseases, the most convincing method for diagnosis to date is surgical biopsy. However, a skin biopsy is an invasive procedure which carries the risk of tissue damage, wound infection and scar formation. To solve the inconvenience from surgical biopsy, multiphoton laser scanning microscopy is a developing, non-invasive method for observing the cutaneous anatomy and pathology. Multiphoton laser scanning microscopy is good in tissue penetration and resolution with less tissue damage. The study aims to compare surgical specimen by conventional pathology slice with the image by non-invasive multiphoton laser scanning microscopy. A good correlation in multiphoton image may serve as optical biopsy for cutaneous pathology and spare the invasive procedure of skin biopsy.

Study Design

Study Type:
Observational
Anticipated Enrollment :
400 participants
Time Perspective:
Other
Official Title:
Multiphoton Laser Scanning Microscopy in Cutaneous Optical Pathology
Study Start Date :
Nov 1, 2002
Anticipated Study Completion Date :
Dec 1, 2012

Outcome Measures

Primary Outcome Measures

    Eligibility Criteria

    Criteria

    Ages Eligible for Study:
    1 Year to 90 Years
    Sexes Eligible for Study:
    All
    Accepts Healthy Volunteers:
    No
    Inclusion Criteria:
    • Patients receiving cosmetic surgeries such as removal of moles
    Exclusion Criteria:
    • No special exclusion criteria

    Contacts and Locations

    Locations

    Site City State Country Postal Code
    1 National Taiwan University Hospital Taipei Taiwan 100

    Sponsors and Collaborators

    • National Taiwan University Hospital
    • National Science Council, Taiwan
    • National Health Research Institutes, Taiwan

    Investigators

    • Principal Investigator: Shiou-Hwa Jee, MD PhD, National Taiwan University Hospital

    Study Documents (Full-Text)

    None provided.

    More Information

    Publications

    None provided.
    Responsible Party:
    , ,
    ClinicalTrials.gov Identifier:
    NCT00508781
    Other Study ID Numbers:
    • 9100206857
    First Posted:
    Jul 30, 2007
    Last Update Posted:
    Jul 30, 2007
    Last Verified:
    Nov 1, 2002

    Study Results

    No Results Posted as of Jul 30, 2007