Investigation of the Effects of Motor Imagery and Action Observation Training in Individuals With Multiple Sclerosis

Sponsor
Hacettepe University (Other)
Overall Status
Not yet recruiting
CT.gov ID
NCT05377476
Collaborator
Bandırma Onyedi Eylül University (Other)
30
1
3
24
1.2

Study Details

Study Description

Brief Summary

It was planned to examine the effects of motor imagery and action observation training applied in addition to standard rehabilitation in individuals with Multiple Sclerosis on walking, fatigue, trunk control and muscle oxygenation.

Condition or Disease Intervention/Treatment Phase
  • Other: Motor Imagery training
  • Other: Action Observation training
  • Other: standard rehabilitation
N/A

Study Design

Study Type:
Interventional
Anticipated Enrollment :
30 participants
Allocation:
Randomized
Intervention Model:
Parallel Assignment
Masking:
Single (Participant)
Primary Purpose:
Treatment
Official Title:
Investigation of the Effects of Motor Imagery and Action Observation Training on Walking, Fatigue, Trunk Control and Muscle Oxygenation in Individuals With Multiple Sclerosis
Anticipated Study Start Date :
Jun 1, 2022
Anticipated Primary Completion Date :
May 1, 2024
Anticipated Study Completion Date :
Jun 1, 2024

Arms and Interventions

Arm Intervention/Treatment
Experimental: Motor Imagery Group

Individuals included in this group will receive 20 minutes of motor imagery training in addition to 40 minutes of standard rehabilitation. Patients will be trained 3 days a week for 6 weeks.

Other: Motor Imagery training
Individuals included in this group will receive 20 minutes of motor imagery training in addition to 40 minutes of standard rehabilitation.

Other: standard rehabilitation
40 minutes of standard rehabilitation.

Experimental: Action Observation Group

Individuals included in this group will receive 20 minutes of action observation training in addition to 40 minutes of standard rehabilitation. Patients will be trained 3 days a week for 6 weeks.

Other: Action Observation training
Individuals included in this group will receive 20 minutes of action observation training in addition to 40 minutes of standard rehabilitation.

Other: standard rehabilitation
40 minutes of standard rehabilitation.

Other: Control Group

Individuals included in this group will receive only 40 minutes of standard rehabilitation. Patients will be trained 3 days a week for 6 weeks.

Other: standard rehabilitation
40 minutes of standard rehabilitation.

Outcome Measures

Primary Outcome Measures

  1. 6 Min Walking Test [6 week]

    It will be used to measure walking capacity. Before the test is applied, necessary information will be given to the individuals and they will be asked to walk as fast as possible for 6 minutes on the 30-meter track.

  2. Timed Up and Go Test [6 week]

    It will be used to assess the functional mobility of individuals. Individuals will be asked to stand up without support from the chair they are sitting in, and to return from the designated area after walking a distance of 3 meters and sit back on the chair without support.

  3. Dynamic Gait Index [6 week]

    It is a scale that evaluates gait balance in MS patients. It examines the balance in completely different walking situations, including daily life activities such as turning the head while walking, taking a step over an obstacle, climbing and descending stairs.

  4. Multiple Sclerosis Walking Scale-12 [6 week]

    It is a scale used to measure walking capacity.

  5. RehaGait® (Hasomed, Magdeburg, Germany) Gait Analysis [6 week]

    The device gives about the time-distance characteristics and kinematic data of the gait.

  6. Fatigue Severity Scale [6 week]

    It is a scale that evaluates the extent to which fatigue affects the daily functions of MS patients.

  7. Trunk Impairment Scale [6 week]

    It is used to evaluate trunk control.

  8. Assessment of the Endurance of Core Muscles [6 week]

    The McGill protocol will be applied to assess the endurance of the core muscles. This protocol consists of a combination of 4 tests; modified Biering-Sorenson test, trunk flexor endurance test, right and left lateral bridge (lateral plank) tests.

  9. Assessment of the Strength of Core Muscles [6 week]

    It will be evaluated with "Sit-ups" and Modified "Push-ups" tests.

Secondary Outcome Measures

  1. Kinesthetic and Visual Imagery Questionnaire [6 week]

    It is a tool used to assess individuals' imagery levels.

  2. Movement Imagery Questionnaire-3 [6 week]

    It is a tool used to assess individuals' imagery levels.

  3. Mental Stopwatch [6 week]

    Mental stopwatch is a method that enables the objective measurement of motor imagery by examining the time difference between the physical execution of the movement (Movement Execution Time, MET) and the mental visualization of the same movement (Movement Imagery Time, MIT).

  4. Measurement of Muscle Oxygenation [6 week]

    It will be measured over the Quadriceps muscle with the MOXY Monitor Device (saturation, Hb values). The Moxy muscle oxygen monitor is a lightweight (42 g) and small (dimensions: 61 × 44 × 21 mm) device that measures regional blood flow and oxygenation by placing it on the skin non-invasively with near infrared spectroscopy (NIRS).

Eligibility Criteria

Criteria

Ages Eligible for Study:
18 Years to 65 Years
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
No
Inclusion Criteria:
  • Being between the ages of 18-65

  • Having a definite diagnosis of MS

  • Expanded Disability Status Scale (EDSS) score of 4.0 and below (it is determined routinely by the physician during the examination)

  • Not having an attack in the last 3 months

Exclusion Criteria:
  • Having another musculoskeletal, cardiovascular, pulmonary, metabolic, or neurological disease severe enough to preclude participation in the study.

  • Having severe vision and hearing problems

  • Presence of severe cognitive impairment detected by the physician at a level that prevents the tests from being performed.

Contacts and Locations

Locations

Site City State Country Postal Code
1 Hacettepe University Ankara Turkey

Sponsors and Collaborators

  • Hacettepe University
  • Bandırma Onyedi Eylül University

Investigators

  • Principal Investigator: Melike Sumeyye Ozen, M.Sc., Bandırma Onyedi Eylül University

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.
Responsible Party:
Melike Sumeyye Ozen, Research Assistant, Bandırma Onyedi Eylül University
ClinicalTrials.gov Identifier:
NCT05377476
Other Study ID Numbers:
  • MSOZEN
First Posted:
May 17, 2022
Last Update Posted:
May 24, 2022
Last Verified:
May 1, 2022
Individual Participant Data (IPD) Sharing Statement:
No
Plan to Share IPD:
No
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No
Keywords provided by Melike Sumeyye Ozen, Research Assistant, Bandırma Onyedi Eylül University
Additional relevant MeSH terms:

Study Results

No Results Posted as of May 24, 2022