The Effect Of Proprioceptive Neuromuscular Facilitation Techniqueson in Patients With Multiple Sclerosis

• Sponsor: Nilay Comuk Balci (Other)
• Overall Status: Completed
• CT.gov ID: NCT06102148
• Collaborator: (none)
• Enrollment: 44
• Location: 1
• Arms: 2
• Actual Duration (Months): 12
• Patients Per Site Per Month: 3.7

Study Details

Study Description

Brief Summary

The aim of this study is to examine the effects of PNF techniques on pain, motor function, fatigue and quality of life.

Condition or Disease	Intervention/Treatment	Phase
Multiple Sclerosis	Other: PNF Group; Other: Control Group	N/A

Study Design

• Study Type: Interventional
• Actual Enrollment: 44 participants
• Allocation: Randomized
• Intervention Model: Parallel Assignment
• Masking: Single (Investigator)
• Primary Purpose: Treatment
• Official Title: The Effect Of Proprioceptive Neuromuscular Facilitation Techniqueson Pain, Motor Functions, Fatique and Health Related Quality of Life in Patients With Multiple Sclerosis: A Randomized, Single-blind Study.
• Actual Study Start Date: Nov 1, 2021
• Actual Primary Completion Date: Nov 1, 2022
• Actual Study Completion Date: Nov 1, 2022

Arms and Interventions

Arm	Intervention/Treatment
Experimental: PNF Group	Other: PNF Group; Exercise training and PNF training
Sham Comparator: Control Group	Other: Control Group; Exercise training

Outcome Measures

Primary Outcome Measures

1. Visual Analogue Scale (VAS) [through study completion, an average of 1 year]

   Pain

2. Multiple Sclerosis Quality of Life-54 (MSQoL-54) [through study completion, an average of 1 year]

   Quality of Life

3. Fatigue Severity Scale and Fatigue Impact Scale (FIS) [through study completion, an average of 1 year]

   Fatigue

4. Timed Up and Go (TUG) [through study completion, an average of 1 year]

   Mobility and Balance

5. The Six-Minute Walk Test (6-MWT) [through study completion, an average of 1 year]

   Functionality

6. Hand Dexterity [through study completion, an average of 1 year]

   Hand Dexterity

Eligibility Criteria

Criteria

• Ages Eligible for Study: 18 Years to 65 Years
• Sexes Eligible for Study: All
• Accepts Healthy Volunteers: No

Inclusion Criteria:

• a clinical diagnosis of Relapsing-Remitting MS (RRMS) as defined by McDonald criteria

• 18-65 years of age

• an Expanded Disability Status Scale (EDSS) score < 4

• relapse-free for the last 3 months

• cognitive impairment that was defined with mini mental test.

Exclusion Criteria:

• a history of different neurological diseases

• having any contraindication for exercise

• having orthopedic, vision, hearing, or perception problems.

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	Ondokuz Mayıs University	Samsun		Turkey	55270

Sponsors and Collaborators

• Nilay Comuk Balci

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

• Responsible Party: Nilay Comuk Balci, Associate professor, Ondokuz Mayıs University
• ClinicalTrials.gov Identifier: NCT06102148
• Other Study ID Numbers: 2021/413
• First Posted: Oct 26, 2023
• Last Update Posted: Oct 26, 2023
• Last Verified: Oct 1, 2023

• Studies a U.S. FDA-regulated Drug Product: No
• Studies a U.S. FDA-regulated Device Product: No
• Keywords provided by Nilay Comuk Balci, Associate professor, Ondokuz Mayıs University: Multiple Sclerosis; Proprioceptive Neuromuscular Facilitation; Pain; Motor Function; Fatigue; Quality of Life
• Additional relevant MeSH terms: Multiple Sclerosis; Sclerosis

Study Results

No Results Posted as of Oct 26, 2023