The Effects of Vestibular Exercise and Cervical Stabilization Exercise Training on Balance and Gait in MS Patients

Sponsor

Sanko University (Other)

Overall Status

Recruiting

CT.gov ID

NCT05409599

Collaborator

(none)

Enrollment

Location

Arms

Anticipated Duration (Months)

3.3

Patients Per Site Per Month

Study Details

Study Description

Brief Summary

The population of this research consists of individuals between the ages of 18-65 with MS disease. MS patients to be included in the study will be directed by the Neurology outpatient clinic of Sanko University Hospital. All volunteers who agreed to participate in this randomized controlled pretest-posttest design study and met the sample criteria will be included in the study.Individuals who agree to participate will be divided into three groups by simple random method and closed envelope method. Vestibular exercise training group will be formed as Group 1 and Cervical stabilization exercise training group as Group 2, control group, and Group 3 as control group.Functional reach test, tandem stand test, 25 step walking test scale form, Multiple Sclerosis Quality of Life Scale form ( MSQOL-54),Fatigue Impact Scale,Beck depression inventory, MS walking scale (msys-12), dizziness disability inventory, four step square test, timed sit and stand test

, 2 minutes walking test be performed before and after treatment,

Condition or Disease	Intervention/Treatment	Phase
Multiple Sclerosis Vestibular Exercises	Other: Exercises	N/A

Detailed Description

Group 1: Vestibular exercise training will be given in addition to conventional treatment (including TENS, electrical stimulation and normal joint range of motion exercises) for 12 weeks. Cawthorne-Cooksey Exercises will be given as a treatment protocol for vestibular exercise training.

Group 2 :Cervical stabilization exercise training will be given in addition to conventional treatment (including Tens, electrical stimulation and normal range of motion exercises) for 12 weeks. Cervical stabilization training improves the sense of cervical proprioception as well as strength and endurance, thereby reducing joint position sense error. Cervical stabilization exercises and training, consisting of 3 stages with increasing difficulty level, will be applied.

Group3: Classical balance exercise training will be given to the control group in addition to conventional treatment (including Tens, electrical stimulation and normal range of motion exercises) for 12 weeks. These exercises were selected among the exercises routinely used in balance rehabilitation in the literature and clinic.

Balance exercise program: walking on tiptoe and heel, walking straight and diagonally on the line, standing on a balance board, supine/prone rolling on the rehabilitation ball, pelvis control in the sagittal and frontal planes on the rehabilitation ball, prone balance on the rehabilitation ball, walking on mats of different softness , was created from side walking exercises.

Study Design

Study Type:

Interventional

Anticipated Enrollment :

36 participants

Allocation:

Randomized

Intervention Model:

Parallel Assignment

Masking:

Single (Participant)

Primary Purpose:

Treatment

Official Title:

Comparison of the Effects of Vestibular Exercise and Cervical Stabilization Exercise Training on Balance and Gait in Multiple Sclerosis Patients

Actual Study Start Date :

Oct 1, 2021

Anticipated Primary Completion Date :

Jul 1, 2022

Anticipated Study Completion Date :

Sep 1, 2022

Arms and Interventions

Arm	Intervention/Treatment
Active Comparator: Cawthorne-Cooksey Exercises Cawthorne-Cooksey Exercises applied to 1st group for 3 days/week for 12 weeks	Other: Exercises Exercises
Active Comparator: cervical stabilization Exercises cervical stabilization Exercises applied to 1st group for 3 days/week for 12 weeks	Other: Exercises Exercises
Active Comparator: classical balance Exercises classical balance Exercises applied to 1st group for 3 days/week for 12 weeks	Other: Exercises Exercises

Arm

Intervention/Treatment

Active Comparator: Cawthorne-Cooksey Exercises

Cawthorne-Cooksey Exercises applied to 1st group for 3 days/week for 12 weeks

Other: Exercises

Exercises

Active Comparator: cervical stabilization Exercises

cervical stabilization Exercises applied to 1st group for 3 days/week for 12 weeks

Other: Exercises

Exercises

Active Comparator: classical balance Exercises

classical balance Exercises applied to 1st group for 3 days/week for 12 weeks

Other: Exercises

Exercises

Outcome Measures

Primary Outcome Measures

Balance [12 weeks]
functional reach test
Gait speed [12 weeks]
25-step walking test
Dizziness [12 weeks]
dizziness disability inventory
Balance [12 weeks]
tandem stance test
Balance [12 weeks]
4 square step test
Endurance [12 weeks]
2-minute walk test
Balance and coordination [12 weeks]
timed sit and stand test
Postural swing [12 weeks]
GYKO
Walkiing difficulty [12 Weeks]
Multiple Sclerosis Walking Scale-12 (MSYS-12)

Secondary Outcome Measures

Fatigue [12 weeks]
fatigue impact scale
Depression [12 weeks]
beck depression inventory
MSQ54 İnventory [12 weeks]
quality of life

Eligibility Criteria

Criteria

Ages Eligible for Study:

18 Years to 65 Years

Sexes Eligible for Study:

All

Accepts Healthy Volunteers:

Inclusion Criteria:

be diagnosed with MS
Not having received physiotherapy-oriented treatment in the last 1 year
not have had an attack in the last 1 month and not be in the attack period

Exclusion Criteria:

having systemic diseases such as hypertension, heart disease, diabetes mellitus, hyperlipidemia, malignancy
individuals whose ambulation is not independent
Those who have undergone any surgery in the last 6 months