Resistance Training and Milk Supplementation

Sponsor

Marymount University (Other)

Overall Status

Completed

CT.gov ID

NCT04509297

Collaborator

University of Tehran (Other)

Enrollment

Location

Arms

Actual Duration (Months)

7.5

Patients Per Site Per Month

Study Details

Study Description

Brief Summary

Post-resistance training high protein milk supplementation may be a viable method to elicit muscular gains.

The investigators hypothesis is that high protein milk supplementation would improve skeletal regulatory markers, hormonal responses and body composition in resistance-trained men.

Condition or Disease	Intervention/Treatment	Phase
Muscular Hypertrophy	Dietary Supplement: high protein milk Dietary Supplement: Placebo	N/A

Detailed Description

The aim of this investigation was to compare the effects of high protein milk supplementation (daily and after training sessions) during 6 weeks of resistance training on skeletal muscle regulatory markers, hormonal responses and body composition in resistance-trained men.

Specific aims of the study are to:

To investigate the extent to which high protein milk supplementation will improve anabolic factors, lean body mass, fat mass and decrease catabolic markers after 6 weeks of resistance training in resistance-trained men.

Study Design

Study Type:

Interventional

Actual Enrollment :

30 participants

Allocation:

Randomized

Intervention Model:

Parallel Assignment

Masking:

Double (Participant, Outcomes Assessor)

Primary Purpose:

Basic Science

Official Title:

Effects of High-protein Milk Supplementation on Muscular Strength and Power, Body Composition, and Skeletal Muscle Regulatory Markers Following Heavy Resistance Training in Resistance-trained Men

Actual Study Start Date :

Jan 4, 2018

Actual Primary Completion Date :

May 5, 2018

Actual Study Completion Date :

May 5, 2018

Arms and Interventions

Arm	Intervention/Treatment
Experimental: High protein milk Experimental: High protein milk consumption This arm involved High protein milk whole consumption concomitant with 6 weeks of resistance training. Subject ingested consumed 1 x 250 mL immediately after resistance training and 1 x 250 mL half an hour before bedtime.	Dietary Supplement: high protein milk This intervention consisted of high protein milk consumption concomitant with 6 weeks of resistance training. Subject ingested consumed 1 x 250 mL immediately after resistance training and 1 x 250 mL half an hour before bedtime. Dietary Supplement: Placebo This intervention consisted of the consumption of a maltodextrin drink with a 9% solution with a vanilla flavor concomitant with 6 weeks of resistance training. Subject ingested consumed 1 x 250 mL immediately after resistance training and 1 x 250 mL half an hour before bedtime.
Placebo Comparator: Placebo This arm involved consumption of a maltodextrin drink with a 9% solution with a vanilla flavor concomitant with 6 weeks of resistance training. Subject ingested consumed 1 x 250 mL immediately after resistance training and 1 x 250 mL half an hour before bedtime. drink r	Dietary Supplement: high protein milk This intervention consisted of high protein milk consumption concomitant with 6 weeks of resistance training. Subject ingested consumed 1 x 250 mL immediately after resistance training and 1 x 250 mL half an hour before bedtime. Dietary Supplement: Placebo This intervention consisted of the consumption of a maltodextrin drink with a 9% solution with a vanilla flavor concomitant with 6 weeks of resistance training. Subject ingested consumed 1 x 250 mL immediately after resistance training and 1 x 250 mL half an hour before bedtime.

Arm

Intervention/Treatment

Experimental: High protein milk

Experimental: High protein milk consumption This arm involved High protein milk whole consumption concomitant with 6 weeks of resistance training. Subject ingested consumed 1 x 250 mL immediately after resistance training and 1 x 250 mL half an hour before bedtime.

Dietary Supplement: high protein milk

This intervention consisted of high protein milk consumption concomitant with 6 weeks of resistance training. Subject ingested consumed 1 x 250 mL immediately after resistance training and 1 x 250 mL half an hour before bedtime.

Dietary Supplement: Placebo

This intervention consisted of the consumption of a maltodextrin drink with a 9% solution with a vanilla flavor concomitant with 6 weeks of resistance training. Subject ingested consumed 1 x 250 mL immediately after resistance training and 1 x 250 mL half an hour before bedtime.

Placebo Comparator: Placebo

This arm involved consumption of a maltodextrin drink with a 9% solution with a vanilla flavor concomitant with 6 weeks of resistance training. Subject ingested consumed 1 x 250 mL immediately after resistance training and 1 x 250 mL half an hour before bedtime. drink r

Dietary Supplement: high protein milk

Dietary Supplement: Placebo

Outcome Measures

Primary Outcome Measures

Circulatory Myokines levels [6 weeks]
Fasting blood samples were collected from the antecubital vein using standard procedures and then analyzed to establish concentration of myostatin and follistatin.
Circulatory hormone levels [6 weeks]
Fasting blood samples were collected from the antecubital vein using standard procedures and then analyzed to establish concentrations of testosterone, IGF-1, growth hormone, insulin and cortisol
Body composition [6 weeks]
Lean body mass and body fatness will be evaluated using bioelectrical impedance

Secondary Outcome Measures

Muscular Strength [6 weeks]
Using a 1 repetition maximum test (defined as the maximal weight an individual can lift for only one repetition) for the bench press and back squat exercises
Muscular Power [6 weeks]
Using the Wingate test

Eligibility Criteria

Criteria

Ages Eligible for Study:

18 Years to 35 Years

Sexes Eligible for Study:

Male

Accepts Healthy Volunteers:

Yes

Inclusion Criteria:

Aged 18-35 years of age
Healthy Males
Experienced at resistance training (at least 1 year of prior structured resistance training 3 x week).

Exclusion Criteria:

smoking
chronic alcohol consumption
having any medical issues and diseases
lactose intolerance
the consumption of any dietary supplements (including vitamins or protein supplements) or medications for 6 months prior to participation

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	Marymount University	Arlington	Virginia	United States	22207

Sponsors and Collaborators

Marymount University
University of Tehran

Investigators

Principal Investigator: Alexei Wong, Marymount University

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

Responsible Party:

Alexei Wong, Assistant Professor, Marymount University

ClinicalTrials.gov Identifier:

NCT04509297

Other Study ID Numbers:

Sports sciences institute.1396

First Posted:

Aug 12, 2020

Last Update Posted:

Aug 12, 2020

Last Verified:

Aug 1, 2020

Individual Participant Data (IPD) Sharing Statement:

Plan to Share IPD:

Studies a U.S. FDA-regulated Drug Product:

Studies a U.S. FDA-regulated Device Product:

Keywords provided by Alexei Wong, Assistant Professor, Marymount University

Additional relevant MeSH terms:

Hypertrophy

Study Results

No Results Posted as of Aug 12, 2020