Blood Flow Within Active Myofascial Trigger Points Following Massage
Study Details
Study Description
Brief Summary
The physiological response at the myofascial trigger point (MTrP) to massage is not known, yet would provide important objective evidence for a treatment effect and clarify the resolution process of a MTrP.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
N/A |
Detailed Description
The physiological response at the myofascial trigger point (MTrP) to massage is not known, yet would provide important objective evidence for a treatment effect and clarify the resolution process of a MTrP. The long-term goal is to understand how therapeutic intervention affects the physiology of the MTrP. The objective of the proposed research is to assess, in a placebo controlled trial, the effectiveness of trigger point release massage (also known as ischemic compression) on blood flow at an active MTrP. The central hypothesis is that the contraction nodule of an active MTrP is characterized by an ischemic state comprised of reduced blood flow and subsequent dysregulation in carbohydrate metabolism. The investigators hypothesize that trigger point release (TPR) can positively impact blood flow leading to a change in high energy carbohydrate tension. The present study has been formulated, in part, from a preliminary study conducted by the investigators, which supports reduced blood flow and physiological disruption at active MTrPs. The proposed research will provide a physiological basis for massage to corroborate subjective reports of reduced pain sensitivity, impart credibility to treatment techniques, and provide insight into a mechanism of action for healing the MTrP.
Study Design
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| Experimental: Trigger point treatment Trigger point release |
Other: Trigger point release
Trigger point therapy
|
| Sham Comparator: Ultrasound Sham US at Trigger point |
Other: Ultrasound
sham ultrasound
|
Outcome Measures
Primary Outcome Measures
- Change in Blood Flow as measured by microdialysis [1 hr pre intervention and 1 hr post intervention]
Secondary Outcome Measures
- Change in Glucose as measured by microdialysis [1 hr pre intervention and 1 hr post intervention]
- Change in Lactate as measured by microdialysis [1 hr pre intervention and 1 hr post intervention]
- Change in Pyruvate as measured by microdialysis [1 hr pre intervention and 1 hr post intervention]
Eligibility Criteria
Criteria
Inclusion Criteria:
-
Chronic or episodic tension-type headache
-
active MTrP in upper trapezius
-
age 21-49
-
BMI between 18.5-24.9
-
either gender
-
any race or ethnicity
Exclusion Criteria:
-
No or latent MTrP in the upper trapezius
-
migraine 4+/month
-
cluster headache
-
fibromyalgia
-
neurological disease (e.g. Alzheimer's disease, Parkinson's disease, muscular dystrophy, multiple sclerosis)
-
cardiovascular disease (e.g. prior heart attack or stroke)
-
diabetes
-
pregnancy
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a bleeding disorder (Self-report of hemophilia, known lack/deficiency of clotting factors, or presently °taking anti-coagulants (e.g. warfarin, Coumadin))
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narcotic use
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currently receiving massage
-
prior trigger point injection or needling therapies
-
allergy to lidocaine-type anesthetics such as lidocaine and prilocaine
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | University of Colorado Hospital | Aurora | Colorado | United States | 80045 |
Sponsors and Collaborators
- University of Colorado, Denver
Investigators
- Principal Investigator: Albert Moraska, PhD, University of Colorado, Denver
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- 14-1582
- UL1TR001082