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The Treatment and Natural History of Acromegaly

Sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (NIH)
Overall Status
Completed
CT.gov ID
NCT00001981
Collaborator
(none)
117
Enrollment
1
Location
349.6
Actual Duration (Months)
0.3
Patients Per Site Per Month

Study Details

Study Description

Brief Summary

The purpose of this study is to investigate the treatment and natural history of acromegaly. We have a longstanding interest in acromegaly treatment, and a cohort that has been followed for 30 years, or more in some cases. We will continue to follow patients and recruit new patients for treatment and follow-up. Blood and pituitary tumor tissue (when available through clinical care) will be saved for future analyses related to acromegaly.

Condition or Disease Intervention/Treatment Phase

    Detailed Description

    The purpose of this study is to investigate the treatment and natural history of acromegaly. We have a longstanding interest in acromegaly treatment, and a cohort that has been followed for 30 years, or more in some cases. We will continue to follow patients and recruit new patients for treatment and follow-up.

    Study Design

    Study Type:
    Observational
    Actual Enrollment :
    117 participants
    Observational Model:
    Cohort
    Time Perspective:
    Prospective
    Official Title:
    Acromegaly Treatment and Natural History
    Actual Study Start Date :
    Oct 2, 1991
    Actual Primary Completion Date :
    Nov 20, 2020
    Actual Study Completion Date :
    Nov 20, 2020

    Arms and Interventions

    Arm Intervention/Treatment
    Patients with acromegaly

    Patients with acromegaly

    Outcome Measures

    Primary Outcome Measures

    1. resolution of IGF-1 Growth Hormone abnormality [every 6 months & at end of study]

      resolution of IGF-1 abnormality

    Eligibility Criteria

    Criteria

    Ages Eligible for Study:
    18 Years and Older
    Sexes Eligible for Study:
    All
    Accepts Healthy Volunteers:
    No
    • INCLUSION CRITERIA:

    Patients will be enrolled who are 18 years of age or over who are referred for care.

    Contacts and Locations

    Locations

    Site City State Country Postal Code
    1 National Institutes of Health Clinical Center, 9000 Rockville Pike Bethesda Maryland United States 20892

    Sponsors and Collaborators

    • National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

    Investigators

    • Principal Investigator: Phillip Gorden, M.D., National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

    Study Documents (Full-Text)

    None provided.

    More Information

    Additional Information:

    Publications

    None provided.
    Responsible Party:
    National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
    ClinicalTrials.gov Identifier:
    NCT00001981
    Other Study ID Numbers:
    • 850082
    • 85-DK-0082
    First Posted:
    Jan 24, 2000
    Last Update Posted:
    Nov 27, 2020
    Last Verified:
    Nov 1, 2020
    Keywords provided by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
    Acromegaly
    Additional relevant MeSH terms:
    Pituitary Neoplasms
    Acromegaly

    Study Results

    No Results Posted as of Nov 27, 2020