How Body Awareness Promotes Mental Health During Yoga and Physical Exercise

Sponsor
Massachusetts General Hospital (Other)
Overall Status
Completed
CT.gov ID
NCT03553745
Collaborator
Yoga Science Foundation (Other), University of Toronto (Other)
71
1
3
35.8
2

Study Details

Study Description

Brief Summary

The integrity of interoceptive networks is linked to resilience against depressive symptoms, whereas degradation of these networks is linked to apathy and deficits in emotion processing. The goal of this study is to compare two major styles of yoga and cardiovascular exercise through a 10-week training program to promote interoceptive awareness. The researchers hypothesize that improvement in affective symptomatology will be correlated with better interoceptive development. Changes in mood related symptoms and interoception will be assessed at baseline, week 12 and week 14, in a cohort of adults aged 18-55.

Condition or Disease Intervention/Treatment Phase
  • Behavioral: Gentle Yoga Intervention
  • Behavioral: Rigorous Yoga Intervention
  • Behavioral: Physical Exercise Intervention
N/A

Detailed Description

A recent annual survey of U.S. college freshman has found consistently declining levels of emotional health over the past 25 years. Exposure to such stress can have profound longitudinal effects on well being, influencing risk for disease later in life. Physical exercise is linked to benefits across a variety of physical and psychological domains. While the affective and physiological consequences of exercise are well-documented, how they work to improve subjective well-being is unclear. It has been suggested that exercise promotes well-being by increasing interoception. The integrity of interoceptive networks is linked to resilience against depressive symptoms, whereas degradation of these networks is linked to apathy and deficits in emotion processing. The goal of this study is to compare two major styles of yoga and cardiovascular exercise through a 10-week training program to promote interoceptive awareness. The researchers hypothesize that improvement in affective symptomatology will be correlated with better interoceptive development. Changes in mood related symptoms and interoception will be assessed at baseline, week 12 and week 14, in a cohort of adults aged 18-55.

Study Design

Study Type:
Interventional
Actual Enrollment :
71 participants
Allocation:
Randomized
Intervention Model:
Parallel Assignment
Masking:
Triple (Participant, Investigator, Outcomes Assessor)
Primary Purpose:
Basic Science
Official Title:
How Body Awareness Promotes Mental Health During Yoga and Physical Exercise
Actual Study Start Date :
Mar 1, 2018
Actual Primary Completion Date :
Feb 23, 2021
Actual Study Completion Date :
Feb 23, 2021

Arms and Interventions

Arm Intervention/Treatment
Experimental: Gentle Yoga Program

Program will meet twice a week for a 10-week period. Participants will be a part of gentle yoga sessions led by instructors specializing in the area.

Behavioral: Gentle Yoga Intervention
10-week exercise program structured around gentle yoga practice.

Experimental: Rigorous Yoga Program

Program will meet twice a week for a 10-week period. Participants will be a part of rigorous yoga sessions led by instructors specializing in the area.

Behavioral: Rigorous Yoga Intervention
10-week exercise program structured around rigorous yoga practice.

Experimental: Cardiovascular Exercise Program

Program will meet twice a week for a 10-week period. Participants will be a part of cardiovascular exercise sessions led by instructors specializing in the area.

Behavioral: Physical Exercise Intervention
10-week exercise program structured around cardiovascular exercise.

Outcome Measures

Primary Outcome Measures

  1. Change in Interoceptive Acuity [14 weeks]

    Interoceptive acuity will be assessed at baseline, week 12 and week 14. Data collection at three time points will be used to assess changes in interoceptive acuity over the timeline.

Secondary Outcome Measures

  1. Peripheral Inflammatory Markers of Stress by collecting Dried Blood Spot (DBS) [14 weeks]

    Dried Blood Spot (DBS) will be collected at baseline, week 12 and week 14. This will be used to assess changes in levels of peripheral markers of inflammation (C-reactive protein, cytokines [IL-6]) in the blood as an indicator of stress.

Eligibility Criteria

Criteria

Ages Eligible for Study:
18 Years to 55 Years
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
Yes
Inclusion Criteria:
  • 18-55 years of age

  • Have negative mood symptoms (depression, anxiety, stress)

  • Is healthy and independent enough in daily life to attend study classes

Exclusion Criteria:
  • Pregnant women or women who are planning to become pregnant during the study period

  • History of structural brain disease, mass lesion, stroke, epilepsy

  • History of addictive disorder or significant substance abuse

  • Neurological disorders or reversible causes of dementia

  • Suicidality or history of psychosis

  • Currently attending regular yoga or aerobic exercise practice, or participated in more than 6 formal meditation, aerobic, or yoga classes in the past 12 months

  • Self-reported cognitive impairment and other disorders which may preclude safe participation in the program including acute major depression, bipolar or severe personality disorder

Contacts and Locations

Locations

Site City State Country Postal Code
1 Massachusetts General Hospital Boston Massachusetts United States 02129

Sponsors and Collaborators

  • Massachusetts General Hospital
  • Yoga Science Foundation
  • University of Toronto

Investigators

  • Principal Investigator: Sara Lazar, PhD, Mass. General Hospital

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.
Responsible Party:
Sara W Lazar, Principal Investigator, Massachusetts General Hospital
ClinicalTrials.gov Identifier:
NCT03553745
Other Study ID Numbers:
  • 2017P001710
First Posted:
Jun 12, 2018
Last Update Posted:
Feb 25, 2021
Last Verified:
Feb 1, 2021
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No
Additional relevant MeSH terms:

Study Results

No Results Posted as of Feb 25, 2021