Neopterin in Acute Coronary Syndrome Patients

• Sponsor: Assiut University (Other)
• Overall Status: Recruiting
• CT.gov ID: NCT05080387
• Collaborator: (none)
• Enrollment: 50
• Location: 1
• Anticipated Duration (Months): 23
• Patients Per Site Per Month: 2.2

Study Details

Study Description

Brief Summary

Measurement of neopterin in ACS patients

Condition or Disease	Intervention/Treatment	Phase
Neopterin in Acute Coronary Syndrome Patients	Other: Blood sample

Detailed Description

1. Detect level of neopterin in ACS patients to detect whether there is relation or not between ACS and neopterin

2. Detection of relation between neopterin and cardiac enzymes as CK and troponine in ACS patients

3. Detect relation between neopterin level and in hospital events

Study Design

• Study Type: Observational
• Anticipated Enrollment: 50 participants
• Observational Model: Case-Control
• Time Perspective: Prospective
• Official Title: Neopterin in Acute Coronary Syndrome Patients
• Anticipated Study Start Date: Nov 1, 2022
• Anticipated Primary Completion Date: Oct 1, 2023
• Anticipated Study Completion Date: Oct 1, 2024

Outcome Measures

Primary Outcome Measures

1. To detect whether there is association between neopterin and ACS or not [72 hours]

   To detect whether there is association between neopterin and ACS or not

Secondary Outcome Measures

1. Detection of relation between neopterin and cardiac enzymes as CK and troponine in ACS and detection of relation between neopterin level and in hospital events [72 hours]

   Detection of relation between neopterin and cardiac enzymes as CK and troponine in ACS and detection of relation between neopterin level and in hospital events

Eligibility Criteria

Criteria

• Ages Eligible for Study: 18 Years to 90 Years
• Sexes Eligible for Study: All

Inclusion Criteria:

• All patient of sample size admitted to cardiology departmentof Assiut university hospital with :

1. Acute typical chest pain

2. Positive cardiac enzymes

3. ECG show recent ischemic changes

4. ECHO show SWMA

Exclusion Criteria:

1. Patients not fulfill inclusion criteria.

2. Patients with other diseases which may cause increase of neopterin level as viral infections, intracellular bacteria or parasites infections, certain malignancies, allograft rejection

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	Assiut university	Assiut		Egypt	AssiutU

Sponsors and Collaborators

• Assiut University

Investigators

• Principal Investigator: Magdy Ibrahim Aldesowky, Lecturer, Assiut University

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

• Responsible Party: Mina Khairy Alyshaa Gorgy, Mina Khairy Alyshaa Gorgy, Assiut University
• ClinicalTrials.gov Identifier: NCT05080387
• Other Study ID Numbers: Neopterin
• First Posted: Oct 15, 2021
• Last Update Posted: Feb 15, 2022
• Last Verified: Oct 1, 2021

• Individual Participant Data (IPD) Sharing Statement: Undecided
• Plan to Share IPD: Undecided
• Studies a U.S. FDA-regulated Drug Product: No
• Studies a U.S. FDA-regulated Device Product: No
• Additional relevant MeSH terms: Acute Coronary Syndrome; Syndrome

Study Results

No Results Posted as of Feb 15, 2022