Study of Pazopanib Monotherapy in Patients With Unresectable, Metastatic Neuroendocrine Tumor

• Sponsor: Samsung Medical Center (Other)
• Overall Status: Completed
• CT.gov ID: NCT01099540
• Collaborator: (none)
• Enrollment: 37
• Location: 1
• Arm: 1
• Duration (Months): 35
• Patients Per Site Per Month: 1.1

Study Details

Study Description

Brief Summary

To determine the response rate of pazopanib when administered as monotherapy in patients with unresectable neuroendocrine tumor.

Condition or Disease	Intervention/Treatment	Phase
Neuroendocrine Tumor	Drug: Pazopanib	Phase 2

Study Design

• Study Type: Interventional
• Actual Enrollment: 37 participants
• Allocation: N/A
• Intervention Model: Single Group Assignment
• Masking: None (Open Label)
• Primary Purpose: Treatment
• Official Title: Phase II Study of Pazopanib Monotherapy in Patients With Unresectable, Metastatic Neuroendocrine Tumor
• Study Start Date: Apr 1, 2010
• Actual Primary Completion Date: Mar 1, 2012
• Actual Study Completion Date: Mar 1, 2013

Arms and Interventions

Arm	Intervention/Treatment
Experimental: Pazopanib	Drug: Pazopanib; Pazopanib 800 mg qd daily

Outcome Measures

Primary Outcome Measures

1. response rate [1~2 year]

Eligibility Criteria

Criteria

• Ages Eligible for Study: 18 Years and Older
• Sexes Eligible for Study: All
• Accepts Healthy Volunteers: No

Inclusion Criteria:

• low to intermediate grade neuroendocrine tumor not amenable to surgery or local therapy

Exclusion Criteria:

• poorly differentiated (high grade or anaplastic)/small cell, pheochromocytoma

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	Samsung Cancer Center	Seoul		Korea, Republic of

Sponsors and Collaborators

• Samsung Medical Center

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

• Responsible Party: Jeeyun Lee, Professor, Samsung Medical Center
• ClinicalTrials.gov Identifier: NCT01099540
• Other Study ID Numbers: 2009-09-090
• First Posted: Apr 7, 2010
• Last Update Posted: Dec 29, 2015
• Last Verified: Dec 1, 2015

• Keywords provided by Jeeyun Lee, Professor, Samsung Medical Center: neuroendocrine tumor
• Additional relevant MeSH terms: Neuroendocrine Tumors

Study Results

No Results Posted as of Dec 29, 2015