Forty Five Patients With Multiple Sclerosis Recieved Vestibular Rehabilitation and Balance Training

Sponsor
October 6 University (Other)
Overall Status
Completed
CT.gov ID
NCT03670459
Collaborator
(none)
45
1
3
8.1
5.5

Study Details

Study Description

Brief Summary

Patients with multiple sclerosis (MS) might develop dizziness or vertigo as a first manifestation or during the course of the illness. Many patients with MS experience chronic or intermittent dizziness. Acute symptoms of dizziness or vertigo in MS fall into two categories; acute vestibular syndrome (AVS) and positional vertigo.

Vestibular disorder due to MS decreases whole body dynamic postural control and causes many functional limitations as limitations in ambulation, dynamic balance and trunk control and that decreases the quality of life.

Vestibular dysfunction has long been recognized as causing some of the most common symptoms in MS, true vertigo is found at presentation in up to 17% of patients, several recent reports have suggested that vestibular symptoms develop early in the disease process. Vestibular Rehabilitation has been shown to be effective in reducing symptoms and improving function for patients with vestibular disorders. The goal of vestibular rehabilitation is to promote the central nervous system compensation through exercise-based strategies.

Condition or Disease Intervention/Treatment Phase
  • Other: Cawthorne Cooksey exercises
  • Other: Vestibular habituation exercises
  • Other: Balance exercises
N/A

Detailed Description

The purposes of the study were to:
  • Measure the effect of Cawthorne Cooksey Exercises on trunk kinetics and velocity of gait in patient with MS.

  • Measure the effect of vestibular habituation on trunk kinetics and velocity of gait in patient with MS.

  • Determine which type of vestibular exercises had more effect on the rehabilitation of patients with MS Cawthorne Cooksey or vestibular habituation?

  • Determine if there was a correlation between the improvement in trunk kinetics and velocity of gait in patients with MS.

Forty five patients with multiple sclerosis were selected from the Out Patient Clinics of Neurology and Internal Medicine in Kasr Al- Aini Hospitals, Out Patient Clinic of Neurology, Faculty of Physical Therapy, Cairo University and 6th of October central hospital.

The selected patients were divided into three equal groups:
  • Patients in G1 will receive traditional physical therapy program (balance training) for twelve sessions; day after day

  • Patients in G2 will receive Cawthorne Cooksey Exercises in addition to traditional physical therapy program for twelve sessions; day after day.

  • Patients in G3 will receive vestibular habituation exercises in addition to traditional physical therapy program for twelve sessions; day after day.

Study Design

Study Type:
Interventional
Actual Enrollment :
45 participants
Allocation:
Randomized
Intervention Model:
Factorial Assignment
Masking:
None (Open Label)
Primary Purpose:
Treatment
Official Title:
Cawthorne Cooksey Versus Vestibular Habituation Exercises on Trunk Kinetics and Velocity of Gait in Patients With Multiple Sclerosis
Actual Study Start Date :
Dec 31, 2017
Actual Primary Completion Date :
Jul 21, 2018
Actual Study Completion Date :
Sep 4, 2018

Arms and Interventions

Arm Intervention/Treatment
Experimental: Group 1

Patients in G1 will receive traditional physical therapy program (balance exercises) for twelve sessions; day after day

Other: Balance exercises
Weight Shift Forward and Back

Experimental: Group 2

Patients in G2 will receive Cawthorne Cooksey Exercises in addition to traditional physical therapy program for twelve sessions; day after day .

Other: Cawthorne Cooksey exercises
Eye movements and head movements

Experimental: Group 3

Patients in G3 will receive vestibular habituation exercises in addition to traditional physical therapy program for twelve sessions; day after day.

Other: Vestibular habituation exercises
Move from a sitting position to flat on the back

Outcome Measures

Primary Outcome Measures

  1. Isokinetic dynamometer [up to 30 days]

    Assessment of trunk kinetics

Eligibility Criteria

Criteria

Ages Eligible for Study:
35 Years to 55 Years
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
No
Inclusion Criteria:
  • All the Patients in this study will be referred from the neurologist and will be diagnosed as relapsing-remitting multiple sclerosis in the form of hemiparesis with muscle tone of 1,1+ modified Ashworth scale.

  • The diagnosis will be confirmed by MRI or CT scan and all the patients will follow the neurological examination.

  • Forty five female patients ages will range from 35-55 years.

  • All selected patients with central vertigo (central vestibular disorder) according to Dix Hallpike test (Cohen, 2004)

  • The Degree of disability of multiple sclerosis will be from 2 - 2.5 (according to expanded disability status scale (EDSS)) (Kaufman et al, 2000)

  • All the selected patients will have grade 3 group muscle test of lower limb muscles.

  • All the selected patients will have scored 27-30 in mini-mental state examination (Crum et al, 1993)

  • Patients who are selected in the study will be ambulant.

  • Patients will be medically stable.

Exclusion Criteria:
  • Patients with musculoskeletal deformity.

  • Patients with diabetes mellitus.

  • Patients with psychological disturbance or seizures.

  • Patients with visual or impairment.

  • Patients with inner ear disorders

  • Patients with other neurological disorders such as cerebellar lesion

Contacts and Locations

Locations

Site City State Country Postal Code
1 October 6 University Giza Egypt 12511

Sponsors and Collaborators

  • October 6 University

Investigators

  • Principal Investigator: Hosam Magdy Metwally, Doctoral, October 6 University

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.
Responsible Party:
Hosam Magdy Metwally, Hossam.magdy.pt@o6u.edu.eg, October 6 University
ClinicalTrials.gov Identifier:
NCT03670459
Other Study ID Numbers:
  • Identifier No. 11
First Posted:
Sep 13, 2018
Last Update Posted:
Sep 13, 2018
Last Verified:
Sep 1, 2018
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No
Additional relevant MeSH terms:

Study Results

No Results Posted as of Sep 13, 2018