QIF: Characterization of Hamstring and Quadriceps Neuromuscular Fatigue After Soccer Game

Sponsor
University Hospital, Strasbourg, France (Other)
Overall Status
Recruiting
CT.gov ID
NCT04943510
Collaborator
(none)
15
1
1
19.8
0.8

Study Details

Study Description

Brief Summary

This is a monocentric study comparing hamstring and quadriceps neuromuscular fatigue after simulated soccer game, anaerobic and aerobic training sessions. The purpose of this study was:

  1. To quantify the decrease of isometric force immediately after a simulate soccer game.

  2. To characterize peripheral and central fatigue between hamstring and quadriceps muscles and described the kinetics of recovery after specific tasks of soccer training.

  3. To compare the level neuromuscular fatigue induced by anaerobic and aerobic training.

  4. To highlight correlation between neuromuscular fatigue and performance markers.

Condition or Disease Intervention/Treatment Phase
  • Other: Physical exercices
Phase 2

Study Design

Study Type:
Interventional
Anticipated Enrollment :
15 participants
Allocation:
N/A
Intervention Model:
Single Group Assignment
Intervention Model Description:
three randomizations will be used to determine the order of the tests that will be proposed to the subjects: on the one hand for the exercise modalities (match, anaerobic, aerobic) and, on the other hand, for the exercise modalities included in the anaerobic and aerobic exercise families: Anaerobic agility / anaerobic - linear sprints Aerobic - shuttle / aerobic - linearthree randomizations will be used to determine the order of the tests that will be proposed to the subjects: on the one hand for the exercise modalities (match, anaerobic, aerobic) and, on the other hand, for the exercise modalities included in the anaerobic and aerobic exercise families: Anaerobic agility / anaerobic - linear sprints Aerobic - shuttle / aerobic - linear
Masking:
None (Open Label)
Primary Purpose:
Basic Science
Official Title:
Characterization of Hamstring and Quadriceps Neuromuscular Fatigue After Different Modality of Training in Soccer Players
Actual Study Start Date :
Nov 4, 2021
Anticipated Primary Completion Date :
Jul 1, 2023
Anticipated Study Completion Date :
Jul 1, 2023

Arms and Interventions

Arm Intervention/Treatment
Experimental: Physical exercices arm

three randomizations will be used to determine the order of the tests that will be proposed to the subjects: on the one hand for the exercise modalities (match, anaerobic, aerobic) and, on the other hand, for the exercise modalities included in the anaerobic and aerobic exercise families: Anaerobic agility / anaerobic - linear sprints Aerobic - shuttle / aerobic - linear

Other: Physical exercices
surface EMG: surface electrodes will be positioned on the muscles to evaluate the level of muscle activation non invasive muscular neurostimulations : application of a percutaneous electrical stimulation of the motor nerve of the considered muscle and a direct electrical stimulation of the muscle
Other Names:
  • Non invasive muscular neurostimulations
  • Surface EMG
  • Outcome Measures

    Primary Outcome Measures

    1. Difference in maximal isometric hamstring strength before and immediately after exercise (i.e., pre vs. immediate post exercise) expressed as a percentage (%). [Before and immediately post exercise (i.e., during the first minute after cessation of exercise)]

    Secondary Outcome Measures

    1. Relative difference (in %) in maximum isometric hamstring strength before and after exercise (i.e., pre- vs. post-exercise), relative to pre-exercise strength across different test types. [Before and immediately post exercise, 5, 10, 15, 30-minutes and 24 and 48-hours post-exercise]

    2. Relative difference (in %) in maximal isometric quadriceps strength before and after exercise (i.e., pre vs. post exercise), related to preexercise strength according to the different types of tests. [Before and immediately post exercise, 5, 10, 15, 30-minutes and 24 and 48-hours post-exercise]

    3. Relative difference (%) in maximum isometric hamstring and quadriceps strength for each test type at the different times of interest. [Before and immediately post exercise, 5, 10, 15, 30-minutes and 24 and 48-hours post-exercise]

    4. Difference in pre- and post-exercise (i.e., pre- vs. post-exercise) hamstring potentiated jerk amplitude (N) relative to pre-exercise amplitude by event type at different times of interest. [Before and immediately post exercise, 5, 10, 15, 30-minutes and 24 and 48-hours post-exercise]

    5. Difference in pre- and post-exercise (i.e., pre- vs. post-exercise) potentiated jerk amplitude (N) of the quadriceps, relative to pre-exercise amplitude, by test type at different times of interest. [Before and immediately post exercise, 5, 10, 15, 30-minutes and 24 and 48-hours post-exercise]

    6. Difference in amplitude of the potentiated jerk (N) before and after exercise, related to the preexercise amplitude according to the muscle involved (hamstrings or quadriceps) and the type of test at different times of interest. [Before and immediately post exercise, 5, 10, 15, 30-minutes and 24 and 48-hours post-exercise]

    7. Difference in the level of voluntary hamstring activation, expressed in newtons (N), before and after exercise, related to the pre-exercise action level, according to the type of test at different times of interest. [Before and immediately post exercise, 5, 10, 15, 30-minutes and 24 and 48-hours post-exercise]

    8. Difference in the level of voluntary quadriceps activation, expressed in newtons (N), before and after exercise, related to the pre-exercise action level, according to the type of test at different times of interest. [Before and immediately post exercise, 5, 10, 15, 30-minutes and 24 and 48-hours post-exercise]

    9. Difference in the level of voluntary action before and after exercise, related to the level of action before exercise, according to the muscle involved (hamstrings or quadriceps) and the type of test at different times of interest. [Before and immediately post exercise, 5, 10, 15, 30-minutes and 24 and 48-hours post-exercise]

    10. Differences in overall fatigue, peripheral fatigue, and central fatigue of hamstrings versus quadriceps between exercise modalities. [Before and immediately post exercise, 5, 10, 15, 30-minutes and 24 and 48-hours post-exercise]

      Determine the modalities of exercises which induce the highest level of fatigue and characterize the etiology of neuromuscular fatigue (i.e., peripheral or central) for typical drills performed daily by elite soccer players

    11. Ratio (%) of initial to post-exercise values based on field indicators and neuromuscular fatigue. [Before and immediately post exercise, 5, 10, 15, 30-minutes and 24 and 48-hours post-exercise]

    Eligibility Criteria

    Criteria

    Ages Eligible for Study:
    16 Years to 40 Years
    Sexes Eligible for Study:
    Male
    Accepts Healthy Volunteers:
    Yes
    Inclusion Criteria:
    • male

    • age limits: minimum: 16 ; maximum: 40 years old

    • to be a soccer player, licensed to the French Football Federation

    • affiliation to the social health insurance scheme

    • signing an informed consent form

    Exclusion Criteria:
    • impossibility to give the subject enlightened information (subject in emergency situation, difficulties in understanding the study, …)

    • subject under the protection of justice

    • subject under guardianship or curatorship

    • lower limbs musculotendinous or articular problems

    • smoker or having been a smoker in the last 5 years

    • subject wearing a pacemaker

    • drug treatment in progress and impossibility to stop it within 7 days before the beginning of the study.

    Contacts and Locations

    Locations

    Site City State Country Postal Code
    1 Hopitaux Universitaires de Strasbourg Strasbourg France 67091

    Sponsors and Collaborators

    • University Hospital, Strasbourg, France

    Investigators

    None specified.

    Study Documents (Full-Text)

    None provided.

    More Information

    Publications

    None provided.
    Responsible Party:
    University Hospital, Strasbourg, France
    ClinicalTrials.gov Identifier:
    NCT04943510
    Other Study ID Numbers:
    • 8168
    First Posted:
    Jun 29, 2021
    Last Update Posted:
    Apr 27, 2022
    Last Verified:
    Apr 1, 2022
    Studies a U.S. FDA-regulated Drug Product:
    No
    Studies a U.S. FDA-regulated Device Product:
    No
    Keywords provided by University Hospital, Strasbourg, France
    Additional relevant MeSH terms:

    Study Results

    No Results Posted as of Apr 27, 2022