Neuronal Correlates of Priming on Goal-directed and Cue-dependent Behavior

• Sponsor: University Hospital Tuebingen (Other)
• Overall Status: Recruiting
• CT.gov ID: NCT03735732
• Collaborator: (none)
• Enrollment: 50
• Location: 1
• Anticipated Duration (Months): 59
• Patients Per Site Per Month: 0.8

Study Details

Study Description

Brief Summary

The current proposal aims to investigate neuronal correlates of implicit and explicit priming paradigms for changing cue-dependent and goal-directed nutritional behavior.

Condition or Disease	Intervention/Treatment	Phase
Functional Magnetic Resonance Imaging; Habits; Eating Behavior	Behavioral: prime

Detailed Description

Food choice and intake is a daily and throughout normal subject. However, for more and more people eating habits and the question of food choice are of increasing interest and in several cases even a problem. The prevalence of obesity has tripled in the last decades and it is even spoken of an obesity epidemic. Life style interventions to lose weight often fail on the long run, also because people fall back into former unhealthy eating habits. Various factors influence our daily food choice, not all of which are apparent to ourselves. Thus, food choice might be goal-directed and therefore conscious and reflective, yet in other circumstances the choice to eat something specific might be based on cue dependent processes which are automatic and thus difficult to control. Since a change in eating-behavior and long-lasting weight loss is most problematic to achieve, the current proposal aims to investigate neuronal correlates of implicit and explicit priming paradigms for changing cue-dependent and goal-directed nutritional behavior.

Study Design

• Study Type: Observational
• Anticipated Enrollment: 50 participants
• Observational Model: Case-Control
• Time Perspective: Cross-Sectional
• Official Title: Neuronal Correlates of Priming on Goal-directed and Cue-dependent Behavior
• Actual Study Start Date: Feb 1, 2019
• Anticipated Primary Completion Date: Jul 1, 2023
• Anticipated Study Completion Date: Jan 1, 2024

Arms and Interventions

Arm	Intervention/Treatment
weight status
mindset	Behavioral: prime; groups be confronted with health or palatability aspects of food items

Outcome Measures

Primary Outcome Measures

1. Change in neuronal correlates [before and 5 minutes after visually presented food items]

   Change of BOLD response measured by fMRI

Eligibility Criteria

Criteria

• Ages Eligible for Study: 20 Years to 50 Years
• Sexes Eligible for Study: All
• Accepts Healthy Volunteers: Yes

Inclusion Criteria:

• experimental: participants with obesity

• control: participants with normal-weight

Exclusion Criteria:

• currently dieting

• intolerance to provided food

• cognitive impairment

• contraindications for fMRI measurements

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	University of Tübingen	Tübingen		Germany

Sponsors and Collaborators

• University Hospital Tuebingen

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

• Responsible Party: Sabine Frank, Research Associate, University Hospital Tuebingen
• ClinicalTrials.gov Identifier: NCT03735732
• Other Study ID Numbers: PIT_brain
• First Posted: Nov 8, 2018
• Last Update Posted: May 18, 2022
• Last Verified: May 1, 2022

• Studies a U.S. FDA-regulated Drug Product: No
• Studies a U.S. FDA-regulated Device Product: No

Study Results

No Results Posted as of May 18, 2022