Neurophysiological Evaluation of Residual Cognitive Functions in Patients With Severe Alterations of Consciousness
Study Details
Study Description
Brief Summary
Identify potential markers of recovery through event-related potentials (ERPs) in the evolution of altered consciousness with potential ability to discriminate between different conditions of altered state of consciousness.
Identify potential markers with prognostic value, in order to identify personalized and specific intensive rehabilitation paths based on the outcome indexes obtained.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
Study Design
Outcome Measures
Primary Outcome Measures
- Event-related evoked potentials(ERPs) [24 months]
Event-related evoked potentials(ERPs) are variations of the electric potential deriving from a visual, somesthetic or auditory stimulus.
Eligibility Criteria
Criteria
Inclusion Criteria:
- Glasgow Coma Scale (GCS) > 8;
Level of Cognitive Scale (LCF) = 1-3;
Signature of the consent from the family member and/or guardian.
Exclusion Criteria:
- Failure to sign the consent of the family member and/or legal guardian;
Patients with cranial anatomical alterations that do not allow the correct assembly of the electrodes, caps, etc.;
Patients with absence of neurophysiological responses in visual evoked potentials (VEP) and with absence of peripheral waves (I-II wave) to acoustic potentials (PEA).
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | IRCCS Centro Neurolesi "Bonino-Pulejo" | Messina | Italy | 98124 |
Sponsors and Collaborators
- IRCCS Centro Neurolesi "Bonino-Pulejo"
Investigators
None specified.Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- Multi-NW