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A New Risk Score for Predicting 1-year Mortality in Older r Maintenance Hemodialysis Patients.

Sponsor
Beijing Friendship Hospital (Other)
Overall Status
Completed
CT.gov ID
NCT05699447
Collaborator
(none)
1,500
Enrollment
1.6
Actual Duration (Months)

Study Details

Study Description

Brief Summary

The goal of this retrospective observational cohort study is to analysis the 1-year mortality in older patients undergoing maintenance hemodialysis. The main question it aims to answer is to explore the risk factors affecting the mortality of older patients undergoing maintenance hemodialysis and establish a risk prediction score.

Data of older patients (age ≥65 years old) undergoing maintenance hemodialysis were collected from 2012-1-December 31, 2014, with data from Beijing Blood Purification Quality Control and Improvement Center (BJHDQCIC). Logistic regression model was used to evaluate the 1-year mortality and the influence of predictive factors. Internal validation of the model was performed using the bootstrap 1000 repeat sampling method. Area under receiver operating characteristic curve (AUC) was used to evaluate the predictive ability of the model.

Condition or Disease Intervention/Treatment Phase

    Study Design

    Study Type:
    Observational
    Actual Enrollment :
    1500 participants
    Observational Model:
    Cohort
    Time Perspective:
    Retrospective
    Official Title:
    A New Risk Score for Predicting 1-year Mortality in Older r Maintenance Hemodialysis Patients.A Cohort Study in Beijing.
    Actual Study Start Date :
    Nov 28, 2022
    Actual Primary Completion Date :
    Jan 10, 2023
    Actual Study Completion Date :
    Jan 16, 2023

    Outcome Measures

    Primary Outcome Measures

    1. the 1-year mortality in older patients undergoing maintenance hemodialysis [Data of older patients (age ≥65 years old) undergoing maintenance hemodialysis were collected from 2012-1-December 31, 2014, with data from Beijing Blood Purification Quality Control and Improvement Center (BJHDQCIC).]

    Eligibility Criteria

    Criteria

    Ages Eligible for Study:
    65 Years and Older
    Sexes Eligible for Study:
    All
    Accepts Healthy Volunteers:
    No
    Inclusion Criteria:

    • Age ≥65 years.

    • More than 6-month history of hemodialysis,the frequency is 3 times a week, and the dialysis time is 4 hours each.

    • The dialysate Ca concentration was 1.5 mmol/L and the bicarbonate level was 32 -- 35 mmol/L.

    Exclusion Criteria:
    • Lack of demographic information, clinical history, or relevant laboratory values (including pre-dialysis serum calcium, phosphorus, iPTH, haemoglobin, albumin, creatinine, total cholesterol, and Kt/v for urea).

    Contacts and Locations

    Locations

    No locations specified.

    Sponsors and Collaborators

    • Beijing Friendship Hospital

    Investigators

    None specified.

    Study Documents (Full-Text)

    None provided.

    More Information

    Publications

    None provided.
    Responsible Party:
    Wenhu Liu, professor, Beijing Friendship Hospital
    ClinicalTrials.gov Identifier:
    NCT05699447
    Other Study ID Numbers:
    • 2022-P2-385-01
    First Posted:
    Jan 26, 2023
    Last Update Posted:
    Jan 26, 2023
    Last Verified:
    Jan 1, 2023
    Studies a U.S. FDA-regulated Drug Product:
    No
    Studies a U.S. FDA-regulated Device Product:
    No
    Keywords provided by Wenhu Liu, professor, Beijing Friendship Hospital
    Older patients
    maintenance hemodialysis
    mortality
    risk prediction score.

    Study Results

    No Results Posted as of Jan 26, 2023