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Normative Database of the Retinal Nerve Fiber Layer Thickness Measured by the Cirrus HD OCT in Asians

Sponsor
Yonsei University (Other)
Overall Status
Unknown status
CT.gov ID
NCT00744705
Collaborator
(none)
200
Enrollment
1
Location
3
Duration (Months)
66.9
Patients Per Site Per Month

Study Details

Study Description

Brief Summary

The normal range of retinal nerve fiber layer thickness might be different between Asians and Caucasians. However, the recently developed imaging device such as the Cirrus HD OCT includes only the Caucasian data. So, the investigators want to find its normal range of in Asians.

Condition or Disease Intervention/Treatment Phase

    Detailed Description

    Characteristics of various ocular parameters are influenced by race. Because the retinal nerve fiber layer (RNFL) thickness is crucial in detecting early glaucomatous changes, its normal range is also important. Even though the normal range of RNFL thickness might be different according to race, the recently developed imaging device such as the Cirrus HD OCT includes only the Caucasian data. In the present study, we want to measure the RNFL thickness using the Cirrus HD OCT in normal Asian eyes and to determine its normal range in Asians.

    Study Design

    Study Type:
    Observational
    Anticipated Enrollment :
    200 participants
    Observational Model:
    Case-Only
    Time Perspective:
    Retrospective
    Official Title:
    Normative Database of the Retinal Nerve Fiber Layer Thickness Measured by the Cirrus HD OCT in Asians
    Study Start Date :
    Sep 1, 2008
    Anticipated Primary Completion Date :
    Nov 1, 2008
    Anticipated Study Completion Date :
    Dec 1, 2008

    Arms and Interventions

    Arm Intervention/Treatment
    1

    Normal subjects who received routine health check-up in a comprehensive medical testing center

    Outcome Measures

    Primary Outcome Measures

    1. Retinal nerve fiber layer thickness [when the OCT images are taking]

    Secondary Outcome Measures

    1. Refractive errors [when the OCT images are taking]

    2. Intraocular pressure [when the OCT images are taking]

    Eligibility Criteria

    Criteria

    Ages Eligible for Study:
    18 Years to 70 Years
    Sexes Eligible for Study:
    All
    Accepts Healthy Volunteers:
    Yes
    Inclusion Criteria:

    • Normal subjects

    • Good quality of the OCT images (signal intensity > 8)

    Exclusion Criteria:

    • Any ocular history

    • DM

    Contacts and Locations

    Locations

    Site City State Country Postal Code
    1 Yongdong Severance Hospital, Yonsei University College of Medicine Seoul Korea, Republic of 135-720

    Sponsors and Collaborators

    • Yonsei University

    Investigators

    • Study Chair: Gong Je Seong, MD, PhD, Yonsei University

    Study Documents (Full-Text)

    None provided.

    More Information

    Publications

    None provided.
    Responsible Party:
    , ,
    ClinicalTrials.gov Identifier:
    NCT00744705
    Other Study ID Numbers:
    • 3-2008-0076-3
    First Posted:
    Sep 1, 2008
    Last Update Posted:
    Sep 1, 2008
    Last Verified:
    Aug 1, 2008
    Keywords provided by , ,
    Retinal nerve fiber layer
    Glaucoma
    Myopia
    Additional relevant MeSH terms:
    Glaucoma

    Study Results

    No Results Posted as of Sep 1, 2008