COVIDIN: Nosocomial COVID-19 Infections in Patients Hospitalized at the Metz-Thionville Regional Hospital in 2021

Sponsor
Centre Hospitalier Régional Metz-Thionville (Other)
Overall Status
Completed
CT.gov ID
NCT05567874
Collaborator
(none)
216
1
7.9
27.4

Study Details

Study Description

Brief Summary

The rate of nosocomial SARS-CoV2 infections found in the different studies since the beginning of the pandemic is very variable (<1% in hospitals in the USA to about 20% in a British hospital). Mortality related to these nosocomial SARS-CoV2 infections is higher than in the general population. The risk factors identified for this nosocomial acquisition are multiple. We were confronted with nosocomial acquisitions and cluster situations in the services, without exhaustive data to measure these phenomena, and we lacked data to consider areas for improvement.

The objectives of this study are to determine the proportion of nosocomial SARS COV 2 infections in the total number of patients hospitalized with a Covid-19 infection at the CHR Metz-Thionville in 2021, and to describe the characteristics of this population.

Condition or Disease Intervention/Treatment Phase
  • Other: Nosocomial SARS-COV 2 Infection proportion

Study Design

Study Type:
Observational
Actual Enrollment :
216 participants
Observational Model:
Cohort
Time Perspective:
Retrospective
Official Title:
Proportion of Nosocomial COVID-19 Infections in Patients Hospitalized at the Metz-Thionville Regional Hospital in 2021
Actual Study Start Date :
Jan 3, 2022
Actual Primary Completion Date :
Mar 31, 2022
Actual Study Completion Date :
Aug 31, 2022

Arms and Interventions

Arm Intervention/Treatment
SARS-CoV 2 infected patients hospitalized at CHR Metz-Thionville in 2021 during the first period

SARS-CoV 2 infected patients hospitalized at CHR Metz-Thionville in April 2021

Other: Nosocomial SARS-COV 2 Infection proportion
Proportion of Nosocomial SARS-COV 2 Infections in Patients Hospitalized at the Metz-Thionville Regional Hospital in 2021

SARS-CoV 2 infected patients hospitalized at CHR Metz-Thionville in 2021 during the second period

SARS-CoV 2 infected patients hospitalized at CHR Metz-Thionville from June to September 2021

Other: Nosocomial SARS-COV 2 Infection proportion
Proportion of Nosocomial SARS-COV 2 Infections in Patients Hospitalized at the Metz-Thionville Regional Hospital in 2021

SARS-CoV 2 infected patients hospitalized at CHR Metz-Thionville in 2021 during the third period

SARS-CoV 2 infected patients hospitalized at CHR Metz-Thionville in December 2021

Other: Nosocomial SARS-COV 2 Infection proportion
Proportion of Nosocomial SARS-COV 2 Infections in Patients Hospitalized at the Metz-Thionville Regional Hospital in 2021

Outcome Measures

Primary Outcome Measures

  1. Proportion of hospital-acquired infections in patients hospitalised with a covid-19 infection [up to 8 months after the third COVID-19 wave]

    Several elements are taken into account: a) the time between entry into the establishment and the first positive SARS COV 2 PCR, b) the time between entry into the establishment and the appearance of the most frequent symptoms (fever, cough), if present in the patient, in the seven days preceding the first positive SARS COV 2 PCR, c) the existence of an epidemiological link with other infected patients, via contact in a double room with another case, and/or via hospitalisation in a department concerned by a cluster situation according to the Santé Publique France definition of May 2020 (identified on the basis of monitoring and surveillance data from the hygiene department).

Secondary Outcome Measures

  1. Description of the nosocomial infected population [up to 8 months after the third COVID-19 wave]

    age, sex, hospital unit care, outcomes of stay, vaccination status, associated conditions (comorbidities according to Charlson score, obesity, pregnancy), existence of screening on admission, time to acquisition of nosocomial infection, number of negative SARS-COV 2 PCRs in the institution before the first positive PCR, type of variant, presence of symptoms (cough, fever), stay in a double room in the 14 days prior to infection, cluster status in the ward, length of stay after infection.

Eligibility Criteria

Criteria

Ages Eligible for Study:
18 Years and Older
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
No
Inclusion Criteria:
  • Patients hospitalised at the CHR Metz-Thionville in medicine, surgery and obstetrics (MCO) or geriatric follow-up and rehabilitation care (SSR) units, in 2021 for a Covid-19 infection defined by the existence of a positive PCR result for SARS-CoV2 during the stay, or by the existence of an ICD10 code for COVID in the PMSI data of the health care establishment
Exclusion Criteria:
  • Opposition to participate in the study after reading the patient information note.

Contacts and Locations

Locations

Site City State Country Postal Code
1 CHR Metz-Thionville/Hopital de Mercy Metz France 57085

Sponsors and Collaborators

  • Centre Hospitalier Régional Metz-Thionville

Investigators

  • Principal Investigator: Mathieu LLORENS, MD, CHR Metz Thionville Hopital de Mercy

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.
Responsible Party:
Centre Hospitalier Régional Metz-Thionville
ClinicalTrials.gov Identifier:
NCT05567874
Other Study ID Numbers:
  • 2022-09Obs-2022
First Posted:
Oct 5, 2022
Last Update Posted:
Oct 7, 2022
Last Verified:
Oct 1, 2022
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No
Additional relevant MeSH terms:

Study Results

No Results Posted as of Oct 7, 2022