Effect of Muscle Damage After Downhill Running on Postprandial Lipids
Study Details
Study Description
Brief Summary
All participants underwent three experimental trials, namely downhill running (DR), level running (LR), and the control (CON) in a cross-over design. Each trial lasted for 2 days. The participants were fed the same breakfast and lunch on day 1 in each trial. The participants arrived at the laboratory at 18:00 on day 1 and ran on the treadmill at 60% VO2max (downhill and level surface trials) or rested (CON trial) for 30 min. Subsequently, they were fed a standardized dinner (A meal box containing chicken, vegetables, and rice, 692 kcal, with 50% energy from carbohydrate, 32% from fat, and 18% from protein) within 20 min.
The participants returned to the laboratory at 07:30 on day 2 after an overnight fast. After baseline blood and gas samples were collected, the participants were fed a high-fat meal that included cereal, white bread, whipping cream, cheese, and butter. The high-fat meal provided fat 1.2 g/kg (65% energy), carbohydrate 1.1 g/kg (27% energy), protein 0.33 g/kg (8% energy), and 16.5 kcal/kg.
A 10-mL blood sample was collected from a forearm vein into nonheparinized tubes before and immediately after exercise or rest on day 1. On day 2, postprandial blood samples were collected from forearm veins into nonheparinized tubes by using an indwelling venous needle and a three-way stopcock. A 10-mL blood sample was collected before (0 h) and 0.5, 1, 2, 3, 4, 5, and 6 h after the high-fat meal.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
N/A |
Study Design
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| Experimental: Downhill running Running at 60% VO2max on -15% slope for 30 min on a treadmill |
Behavioral: Exercise
Running
|
| Experimental: Level running Running at 60% VO2max on level surface for 30 min on a treadmill |
Behavioral: Exercise
Running
|
| Placebo Comparator: Control Rest 30 min |
Behavioral: Rest
sit and rest
|
Outcome Measures
Primary Outcome Measures
- TG AUC [6 hours]
area under the curve for serum triglyceride concentrations within 6 hours after the high-fat meal
Secondary Outcome Measures
- NEFA AUC [6 hours]
area under the curve for serum non-esterified fatty acid concentrations within 6 hours after the high-fat meal
Eligibility Criteria
Criteria
Inclusion Criteria:
- generally healthy, had not engaged in regular exercise or received any medication in the past 6 months
Exclusion Criteria:
- history of cardiovascular disease, hypertension, hyperlipidemia, diabetes, atherosclerosis, or osteoporosis, free of any musculoskeletal injury during the study
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | National Taiwan University of Sport | Taichung | Taiwan | 404 |
Sponsors and Collaborators
- National Taiwan Sport University
Investigators
None specified.Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- 201903HM011