Comparative Effects of Using Black Seed and Cumin Seed on BCP of Obese Grade I
Study Details
Study Description
Brief Summary
The goal of this Randomized clinical trial is to compare effectiveness of of using black seed (Nigella sativa) and cumin seed (Cuminum cyminum) on Body composition profile of obese grade
- The primary objective of this study is To compare effectiveness of of using black seed (Nigella sativa) and cumin seed (Cuminum cyminum) on Body composition profile of obese grade
- Subjects will be given a consent form and after subjects read and sign the informed consent, they would be included in study according to eligibility criteria.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
Phase 1 |
Detailed Description
Obesity is a global pandemic that is associated with high morbidity and mortality. Natural herbs are commonly used for weight reduction and appetite suppression. Worldwide data based on 1698 studies has shown that the global prevalence of obesity has increased from 3.2 to 10.8% in men and from 6.4 to 14.9% in women. Meanwhile, herbal products are marketed for their weight-loss properties, such as Nigella sativa which has been used for centuries to treat rheumatoid arthritis, diabetes, and asthma; recently, the anti-obesity characteristics of N. sativa have also been indicated. The antihyperglycemic activity, inhibition of free radical formation, anti-obesity and anti-inflammatory activity of cumin seed extract have also been reported previously.
Study Design
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| Active Comparator: Group A Group A Obese Grade I |
Dietary Supplement: Black Seed ( Nigella Sativa)
Intervention will be given once a day for 1 month, total 30 days Data will be collected at baseline and at the end of the intervention at 30th day
|
| Active Comparator: Group B Group B Obese Grade I |
Dietary Supplement: Cumin Seed (Cuminum Cyminum)
Intervention will be given once a day for 1 month, total 30 days Data will be collected at baseline and at the end of the intervention at 30th day
|
Outcome Measures
Primary Outcome Measures
- Body Composition Profile [Change from baseline at 30th Day]
permits a detailed analysis of the body's major structural components like muscle mass, fat, and bone. It is measured in percentage.
Secondary Outcome Measures
- BMI [Change from Baseline at 30th Day]
Body mass index is a value derived from the mass and height of a person. The BMI is defined as the body mass divided by the square of the body height, and is expressed in units of kg/m², resulting from mass in kilograms and height in metres
Eligibility Criteria
Criteria
Inclusion Criteria:
- Subject having BMI between 30 kg/m2 - 34.5 kg/m2
Exclusion Criteria:
-
Subjects having kidney or liver problems
-
Having ulcers in GIT
-
Subjects having hypertension, thyroid, diabetes or cardiovascular disorders
-
Pregnant and lactating mothers
-
Subjects who are using hormonal or anti-obesity medications
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | Sehat Medical Complex, Lahore | Lahore | Punjab | Pakistan | 55201 |
Sponsors and Collaborators
- Sehat Medical Complex
Investigators
- Principal Investigator: Momina Mehmood, University of Lahore
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- ZaraYameen001-23