The Effect of the DASH Diet Containing Meat on Muscle and Metabolic Health in Older Adults

Sponsor
South Dakota State University (Other)
Overall Status
Completed
CT.gov ID
NCT04127240
Collaborator
(none)
46
1
2
16.9
2.7

Study Details

Study Description

Brief Summary

Age-related changes in body composition, muscular fitness, and metabolic health resulting in the onset of obesity, sarcopenia, and chronic diseases are profound public health issues that are in need of immediate attention. Effective and feasible methods, such as dietary therapies, are needed to improve health in older adults that in turn lead to independence, enhanced quality of life and reduced hospitalizations. Diet quality and dietary protein intake are vital for maintaining body composition, muscle mass and improved physical performance. Malnutrition in dietary protein intake is a major cause of reduced muscle mass, strength, and function in older adults. The Dietary Approaches to Stop Hypertension (DASH) dietary pattern is a high-quality therapeutic diet known to improve health status in various diverse and at-risk populations resulting in improved heart health, maintained cognitive function and reductions in metabolic diseases such as diabetes, metabolic syndrome, and nonalcoholic fatty liver disease. The primary protein recommendations of the DASH diet are poultry and fish and it is recommended to decrease or exclude red meats from the diet. However, studies have demonstrated that lean red meat incorporated into a DASH-like diet doesn't exacerbate cardiovascular health indices in adults, indicating that lean red meat can be included in the DASH diet without negative effects on heart health. Although studies have reported on the DASH diet in older adults, no studies have investigated the effect of the DASH diet containing lean red meat on measures of body composition, muscle mass or metabolic health under controlled-feeding conditions. The purpose of this study was to determine the effect of the DASH diet containing daily intakes of lean red meat on indicators of body composition, muscular fitness and biomarkers of metabolic health in adults 65 and older using controlled-feeding and systems biology approaches.

Condition or Disease Intervention/Treatment Phase
  • Other: DASH diet containing daily intakes of red meat
N/A

Study Design

Study Type:
Interventional
Actual Enrollment :
46 participants
Allocation:
Randomized
Intervention Model:
Parallel Assignment
Masking:
Single (Participant)
Primary Purpose:
Other
Official Title:
The Effect of Meat Intake as a Part of the DASH Diet on Indices of Muscular Fitness, Body Composition and Metabolic Health in Adults 65 and Older: A Controlled-Feeding Systems-Biology Study
Actual Study Start Date :
Jun 15, 2017
Actual Primary Completion Date :
Nov 10, 2018
Actual Study Completion Date :
Nov 10, 2018

Arms and Interventions

Arm Intervention/Treatment
Experimental: Meat assignment in DASH intervention

Participants consumed 3 ounces of red meat per day as a part of the DASH diet.

Other: DASH diet containing daily intakes of red meat
Each participant was randomized to consume 3 or 6 ounces of red meat as a part of the DASH dietary pattern for 12-weeks.

Experimental: Meat allocation in DASH intervention

Participants consumed 6 ounces of red meat per day as a part of the DASH diet.

Other: DASH diet containing daily intakes of red meat
Each participant was randomized to consume 3 or 6 ounces of red meat as a part of the DASH dietary pattern for 12-weeks.

Outcome Measures

Primary Outcome Measures

  1. Body weight [Change in body weight from baseline to 3 months]

    Measured by bioelectrical impedance

  2. Hand grip strength [Change in strength from baseline to 3 months]

    Measured by a hand-held dynamometer

  3. Glucose [Change in glucose concentrations from baseline to 3 months]

    Measure serum glucose using colorimetry assay

Eligibility Criteria

Criteria

Ages Eligible for Study:
65 Years and Older
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
Yes
Inclusion Criteria:
  • 65 and older

  • Upward mobile ability

Exclusion Criteria:
  • Under the age of 65

  • Immobility

Contacts and Locations

Locations

Site City State Country Postal Code
1 South Dakota State University Brookings South Dakota United States 57006

Sponsors and Collaborators

  • South Dakota State University

Investigators

  • Principal Investigator: Cydne A Perry, PhD, South Dakota State University

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.
Responsible Party:
Cydne Perry, Assistant Professor, South Dakota State University
ClinicalTrials.gov Identifier:
NCT04127240
Other Study ID Numbers:
  • 1712006
First Posted:
Oct 15, 2019
Last Update Posted:
Oct 15, 2019
Last Verified:
Oct 1, 2019
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No
Additional relevant MeSH terms:

Study Results

No Results Posted as of Oct 15, 2019