Dose-Response of Exercise on Long-Term Weight Loss
Study Details
Study Description
Brief Summary
The purpose is to examine varying durations and intensities of exercise on long-term weight loss.
Condition or Disease | Intervention/Treatment | Phase |
---|---|---|
|
Phase 1/Phase 2 |
Study Design
Outcome Measures
Primary Outcome Measures
- weight loss []
Secondary Outcome Measures
- fitness []
- dietary intake []
- physical activity []
- mediators []
- body composition []
Eligibility Criteria
Criteria
Inclusion Criteria:
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Female
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21-45 years of age
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BMI = 27-40 kg/m2
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Ability to provide informed consent.
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Ability to provide consent from their personal physician to participate in this study.
Exclusion Criteria:
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Reporting regular exercise participation of at least 20 minutes per day on at least 3 days per week during the previous six months. (This study is designed to recruit relatively sedentary adults.)
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Diabetes, hypothyroidism, or other medical conditions which would affect energy metabolism.
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Currently pregnant, pregnant within the previous six months, or planning on becoming pregnant within the next 24 months. (Pregnancy will be based on self-report and will be included on the detailed medical history that is completed by subjects.)
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Non-medicated resting systolic blood pressure >160 mmHg or non-medicated resting diastolic blood pressure >100 mmHg, or taking medication that would affect blood pressure.
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Taking medication that would affect resting heart rate or the heart rate response during exercise (e.g., beta blockade).
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Arrhythmia on resting or exercise electrocardiogram that would indicate that vigorous exercise was contraindicated.
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History of myocardial infarction or valvular disease.
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History of orthopedic complications that would prevent optimal participation in the exercise component (e.g., heel spurs, severe arthritis).
Contacts and Locations
Locations
Site | City | State | Country | Postal Code | |
---|---|---|---|---|---|
1 | University of Pittsburgh | Pittsburgh | Pennsylvania | United States | 15203 |
Sponsors and Collaborators
- University of Pittsburgh
- National Institutes of Health (NIH)
Investigators
- Principal Investigator: John M Jakicic, Ph.D., University of Pittsbugh
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- R01HL064991