GALILEOhealthy: Observation of Acute Cardiopulmonary Effects in Healthy Individuals Performing Cardiopulmonary Exercise Test (CPX) During Whole Body Vibration (WBV)

Sponsor

Klinikum der Universität Köln (Other)

Overall Status

Unknown status

CT.gov ID

NCT04162054

Collaborator

(none)

Enrollment

Location

Anticipated Duration (Months)

2.9

Patients Per Site Per Month

Study Details

Study Description

Brief Summary

Observational study to evaluate acute cardiopulmonary effects of oscillatory whole body vibration (WBV) on healthy individuals analysed in non-invasive cardiopulmonary exercise test (CPX).

Condition or Disease	Intervention/Treatment	Phase
Acute Cardiopulmonary Effects	Other: Observational study to evaluate acute cardiopulmonary effects of whole body vibration (WBV) on healthy individuals analysed in non-invasive cardiopulmonary exercise test (CPX).

Detailed Description

Oscillatory whole-body vibration (WBV) is a novel exercise modality, which is performed on a vibrating platform that moves in sinusoidal oscillations, and during which static and dynamic exercises can be performed. Rapid movements of the platform lead to muscle spindle reﬂexes, which result in reﬂectory contraction of muscle groups and thus promote gain of muscle strength and power. The most efﬁcient vibration rate enhancing muscle function is assumed to be ∼20 Hz, leading to constant muscle contraction and anaerobic metabolism of the affected muscle ﬁbres. As a consequence, lactate liberation serves as a stimulus for muscle gain.This methodology has been successfully utilised to enhance moving velocity, muscle power and strength in young athletes and chronic obstructive pulmonary disease though not been understood in all details. Therefore this investigation will help to evaluate acute cardiopulmonary effects of whole body vibration (WBV) on healthy individuals analysed in non-invasive cardiopulmonary exercise test (CPX).

Study Design

Study Type:

Observational

Anticipated Enrollment :

20 participants

Observational Model:

Cohort

Time Perspective:

Prospective

Official Title:

Observation of Acute Cardiopulmonary Effects in Healthy Individuals Performing Cardiopulmonary Exercise Test (CPX) During Whole Body Vibration (WBV)

Anticipated Study Start Date :

Mar 1, 2020

Anticipated Primary Completion Date :

Sep 30, 2020

Anticipated Study Completion Date :

Sep 30, 2020

Outcome Measures

Primary Outcome Measures

Peak VO2 in mililiter [one day]
maximal Oxygen saturation

Secondary Outcome Measures

Nadir Co2 at anaerobic threshold [one day]
Nadir Co2 in mmHG
anaerobic threshold (AT) [one day]
AT in mililiter

Eligibility Criteria

Criteria

Ages Eligible for Study:

18 Years to 45 Years

Sexes Eligible for Study:

All

Accepts Healthy Volunteers:

Yes

Inclusion Criteria:

healthy individuals planning on performing a WBV-Training
healthy individuals planning on performing a CPX

Exclusion Criteria:

exclusion to perform CPX
exclusion to perform WBV

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	Spezialambulanz für pulmonale Hypertonie Uniklinik Köln	Köln	NRW	Germany	50937

Sponsors and Collaborators

Klinikum der Universität Köln

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

Responsible Party:

Felix Gerhardt, Dr. med., Klinikum der Universität Köln

ClinicalTrials.gov Identifier:

NCT04162054

Other Study ID Numbers:

First Posted:

Nov 14, 2019

Last Update Posted:

Jan 23, 2020

Last Verified:

Jan 1, 2020

Individual Participant Data (IPD) Sharing Statement:

Undecided

Plan to Share IPD:

Undecided

Studies a U.S. FDA-regulated Drug Product:

Studies a U.S. FDA-regulated Device Product:

Study Results

No Results Posted as of Jan 23, 2020