Obstructive Sleep Apnea Airway Evaluation
Study Details
Study Description
Brief Summary
Current practice guidelines recommend obstructive sleep apnea (OSA) patients to stay in the post anesthetic care unit (PACU) until the risk of respiratory depression has subsided. Inevitably, a greater demand on hospital resource utilization in these patients will increase health care cost. Polysomnography (PSG) and screening questionnaires can identify OSA but they are limited by accessibility and false positive results, respectively. Inaccurate OSA identification misguides postoperative surveillance plan. In contrast with MRI and CT scans, ultrasound is more accessible and more likely a practical tool for OSA screening. However, before clinical application, airway ultrasound (US) exam must undergo vigorous testing to check its utility, accuracy, inter-observer reliability and its ability to identify OSA and its severity.
| Condition or Disease | Intervention/Treatment | Phase |
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Detailed Description
The investigators plan to recruit surgical patients at risk of OSA, exposed to sedatives,and/or general anesthesia. Surface ultrasound measurements will be conducted in a separate setting, and be correlated with the sleep study results, and a set of ultrasound parameters will be validated in this setting. Relevant clinical outcomes will be captured as well.
Study Design
Outcome Measures
Primary Outcome Measures
- Correlation of airway parameter measurements with Apnea-Hypopnea Index (AHI) values on Polysomnography (PSG) [2 years]
Airway parameters will be measured and correlated with sleep apnea severity as indicated by AHI values obtained from PSG test
Secondary Outcome Measures
- Feasibility of airway Ultrasound (US) examination; [2 years]
Time required to do an ultrasound scan of the airway and consistency of airway parameter measurements will be assessed
Eligibility Criteria
Criteria
Inclusion Criteria:
- Age>=18 American Society of Anesthesiologists (ASA) Physical System Classification 1-4 Suspected OSA / STOP-Bang questionnaire score for sleep apnea > 3 Referred for PSG / Had sleep study in past 1 year (amendment authorized 20/12/2017)
Exclusion Criteria:
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• failure to understand and provide consent
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past history of oral, head and neck surgery (e.g., OSA corrective surgery)
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active head & neck disease (e.g., cancer, infection and radiotherapy);
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inability to perform breathing tests per instruction / on OSA treatment
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | Toronto Western Hospital | Toronto | Ontario | Canada |
Sponsors and Collaborators
- University Health Network, Toronto
- Hospital for Special Surgery, New York
Investigators
- Principal Investigator: Mandeep Singh, Department of Anesthesia, Toronto Western Hospital- UHN, University of Toronto
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- 16-6160