Internet-delivered CBT for Adolescents With Obsessive-Compulsive Disorder - a Pilot Study
Study Details
Study Description
Brief Summary
The main goal of this trial is to study the feasibility and effectiveness of internet-delivered cognitive behavior therapy for adolescents with obsessive-compulsive disorder.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
N/A |
Study Design
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| Experimental: internet-delivered cognitive behavior therapy Participants will be assigned to a 12 weeks internet-delivered cognitive behavior therapy program including therapist contact via an internet platform and telephone. |
Behavioral: Internet-delivered Cognitive Behavior Therapy
|
Outcome Measures
Primary Outcome Measures
- Children's Yale Brown Obsessive Compulsive Scale, CY-BOCS [Baseline, 12 weeks after treatment starts, 3 and 6 months after treatment has ended]
Change from Baseline of obsessions and compulsions after 12 weeks and at 3- and 6 months after treatment.
Secondary Outcome Measures
- Spence Child Anxiety Scale - Child and Parent version [Baseline, 12 weeks after treatment starts, 3 and 6 months after treatment has ended]
Spence Child Anxiety Scale - Child and Parent version (SCAS/P, Spence, 1998) will be used as a child and parent self-report measure of anxiety related psychopathology.
- Child Depression Inventory [Baseline, 12 weeks after treatment starts, 3 and 6 months after treatment has ended]
Symptom severity of depression in the adolescent will be assessed with Child Depression Inventory (CDI, Kovacs, 1985).
- Strengths Difficulties Questionnaire [Baseline, 12 weeks after treatment starts, 3 and 6 months after treatment has ended]
Strengths Difficulties Questionnaire (SDQ, Goodman, 1997) is a widely used self- and parent-report behavioral screening questionnaire with six subscales: emotional problems, conduct problems, hyperactivity-inattention, peer problems, prosocial behavior
- Children's Obsessional Compulsive Inventory Revised [Baseline, 12 weeks after treatment starts, 3 and 6 months after treatment has ended]
The Children's Obsessional Compulsive Inventory Revised, (CHOCI-R, Shafran et al., 2003) is a self- and parent-report measure of pediatric OCD symptom severity.
- Child Obsessive-Compulsive Impact Scale - Revised [Baseline, 12 weeks after treatment starts, 3 and 6 months after treatment has ended]
Child Obsessive-Compulsive Impact Scale - Revised (COIS-R, Piacentini, Peris, Bergman, Chang, & Jaffer, 2007) is a self- and parent-report scale of OCD symptom impact on everyday life.
Other Outcome Measures
- Patient Health Questionnaire PHQ-9 [Baseline, 12 weeks after treatment starts, 3 and 6 months after treatment has ended]
Patient Health Questionnaire PHQ-9 (Kroenke, Spitzer, & Williams, 2001) is a brief self-report measure of depressive symptoms in adults. PHQ-9 will be used to measure parental depressive symptoms.
- GAD-7 [Baseline, 12 weeks after treatment starts, 3 and 6 months after treatment has ended]
GAD-7 (Spitzer, Kroenke, Williams, & Löwe, 2006) is a brief self-report measure of symptoms of general anxiety in adults. GAD-7 will be used to measure symptoms of anxiety in the parents.
- Obsessive Compulsive Inventory - Revised [Baseline, 12 weeks after treatment starts, 3 and 6 months after treatment has ended]
Obsessive Compulsive Inventory - Revised (OCI-R, Foa et al., 2002) is a reliable and valid 18-item self-report scale for screening of OCD in adults and will be used to measure parental OC symptoms of both parents.
- Family Accommodation Scale, Parent-Report [Baseline, 12 weeks after treatment starts, 3 and 6 months after treatment has ended]
Family Accommodation Scale, Parent-Report (FAS-PR, Flessner et al., 2009). The parent-report version of the FAS consists of 12 items focusing on accommodation behaviors of parents with a child with OCD.
Eligibility Criteria
Criteria
Inclusion Criteria:
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a primary diagnosis of OCD as defined by DSM-IV TR
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a total score of above 15 on the CY-BOCS
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age between 12 and 17 years
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ability to read and write Swedish
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daily access to the internet
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a parent that is able to co-participate in the treatment
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Participants on psychotropic medication must have been on a stable dose for the last 6 weeks prior to baseline assessment
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signed informed consent
Exclusion Criteria:
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diagnosed autism spectrum disorder, psychosis or bipolar disorder
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suicidal ideation
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ongoing substance dependence
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subject not able to read or understand the basics of the ICBT self-help material
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completed CBT for OCD within last 12 months (defined as at least 5 sessions CBT including exposure and response prevention)
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ongoing psychological treatment for OCD or another anxiety disorder
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | Karolinska insititute | Stockholm | Sweden |
Sponsors and Collaborators
- Eva Serlachius
- Region Stockholm
Investigators
- Principal Investigator: Eva Serlachius, PhD, MD, Karolinska Institutet
Study Documents (Full-Text)
None provided.More Information
Publications
- Flessner CA, Sapyta J, Garcia A, Freeman JB, Franklin ME, Foa E, March J. Examining the Psychometric Properties of the Family Accommodation Scale-Parent-Report (FAS-PR). J Psychopathol Behav Assess. 2009 Mar;31(1):38-46.
- Foa EB, Huppert JD, Leiberg S, Langner R, Kichic R, Hajcak G, Salkovskis PM. The Obsessive-Compulsive Inventory: development and validation of a short version. Psychol Assess. 2002 Dec;14(4):485-96.
- Goodman R. The Strengths and Difficulties Questionnaire: a research note. J Child Psychol Psychiatry. 1997 Jul;38(5):581-6.
- Kovacs M. The Children's Depression, Inventory (CDI). Psychopharmacol Bull. 1985;21(4):995-8.
- Kroenke K, Spitzer RL, Williams JB. The PHQ-9: validity of a brief depression severity measure. J Gen Intern Med. 2001 Sep;16(9):606-13.
- Piacentini J, Peris TS, Bergman RL, Chang S, Jaffer M. Functional impairment in childhood OCD: development and psychometrics properties of the Child Obsessive-Compulsive Impact Scale-Revised (COIS-R). J Clin Child Adolesc Psychol. 2007 Oct-Dec;36(4):645-53.
- Scahill L, Riddle MA, McSwiggin-Hardin M, Ort SI, King RA, Goodman WK, Cicchetti D, Leckman JF. Children's Yale-Brown Obsessive Compulsive Scale: reliability and validity. J Am Acad Child Adolesc Psychiatry. 1997 Jun;36(6):844-52.
- Shafran R, Frampton I, Heyman I, Reynolds M, Teachman B, Rachman S. The preliminary development of a new self-report measure for OCD in young people. J Adolesc. 2003 Feb;26(1):137-42.
- Spence SH. A measure of anxiety symptoms among children. Behav Res Ther. 1998 May;36(5):545-66.
- Spitzer RL, Kroenke K, Williams JB, Löwe B. A brief measure for assessing generalized anxiety disorder: the GAD-7. Arch Intern Med. 2006 May 22;166(10):1092-7.
- BIPOCD1