Pharmacist-Led Interventions to Increase Access to Medications for Opioid Use Disorders (PLI-MOUD)
Study Details
Study Description
Brief Summary
The purpose of this study is to investigate the impact of a pharmacist-led intervention to expand access to medications for opioid use disorder (MOUD) on racial/ethnic differences in opioid-related overdose among individuals diagnosed with opioid use disorder (OUD) currently incarcerated in a carceral setting. In this study, participants will be screened for opioid use, trained to administer Narcan nasal spray, receive motivational counseling and referral to treatment post-release from a carceral setting (a Re-Entry program) into the community.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
N/A |
Detailed Description
The main objectives of this study are:
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To increase understanding of racial/ethnic differences in the prevalence of OUD.
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To test if a pharmacist-led intervention is more effective than a substance use counselor (lay person) in increasing knowledge and confidence among different racial/ethnic groups related to administering Narcan nasal spray in an opioid overdose situation.
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To test if a pharmacist-delivered an evidence-based intervention, q brief intervention and referral to treatment (BIRT) versus standard medication counseling (SMC) is more effective in increasing access to MOUD.
Study Design
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| Experimental: Pharmacist Narcan Training Pharmacist-led intervention |
Behavioral: Pharmacist Narcan Training
A 20-45-minute didactic presentation conducted with a skills training component designed to demonstrate appropriate administration of the Narcan nasal spray.
|
| Active Comparator: Substance Use Counselor Narcan Training Non-clinician intervention |
Behavioral: Substance Use Counselor Narcan Training
A 20-45-minute didactic presentation conducted with a skills training component designed to demonstrate appropriate administration of the Narcan nasal spray.
|
| Experimental: Brief Intervention and Referral to Treatment (BIRT) BIRT intervention |
Behavioral: BIRT
BIRT participants will receive a 30-45-minute session delivered by the pharmacist to introduce and encourage treatment options, MOUD information, OUD information, and treatment facility information (i.e., flyers (RDD study/CAST clinic/State Opioid Response III funded agencies) and educational materials), and a referral to treatment/linkage to service providers.
|
| Active Comparator: Standard Medication Counseling (SMC) SMC intervention |
Behavioral: SMC
SMS participants will receive a 5-10-minute counseling session delivered by the pharmacist providing MOUD information, OUD information, and treatment facility information (i.e., flyers (RDD study/CAST clinic/State Opioid Response III funded agencies) and educational materials).
|
Outcome Measures
Primary Outcome Measures
- Opioid overdose training [at month 6]
Participants' knowledge about opioid overdose and confidence to recognize and respond to opioid overdose situations as a function of the trainer. Participants will complete a brief validated survey, the adapted Perceived Competence Scale. The questions on the survey are rated on a 7-point scale and participants indicate how true four statements are about their ability to recognize and respond to overdoses: the scale, 1 (not at all true) to 7 (very true).
- Retention [at month 6]
Participants, regardless of treatment arm, will receive follow-up telephone interviews at 6 months post-release from the carceral setting into the community. Interviews will address the primary question whether MOUD treatment was initiated and maintained.
Eligibility Criteria
Criteria
Inclusion Criteria
Narcan Training:
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a Re-Entry program participant 7-14 days from release from carceral setting
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provide collateral contact information for ≥2 persons (to ensure consistent contact/follow up)
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have a reliable landline or mobile phone to be contacted by pharmacist
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plan to remain in the Little Rock area for at least 6 months
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able to read and write English
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able to provide informed consent
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possesses manual dexterity; physical ability to roll a person onto her/his/their back and side
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have no allergy to naloxone hydrochloride (active ingredient in Narcan nasal spray)-
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identified on the RODS screener as positive for OUD.
BIRT/SMC:
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a Re-Entry program participant 7-14 days from release from the carceral setting
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provide contact information for ≥2 persons (to ensure consistent contact/follow -up)
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have a reliable landline or mobile phone to be contacted by pharmacist
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plan to remain in the Little Rock area for at least 6 months
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able to read and write English; able to provide informed consent
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identified with OUD.
Exclusion Criteria:
Narcan training:
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not a RE-entry program participant
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identified substance use disorders other than OUD
BIRT/SMC:
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not a RE-entry program participant
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identified substance use disorders other than OUD
Contacts and Locations
Locations
No locations specified.Sponsors and Collaborators
- University of Arkansas
Investigators
- Principal Investigator: Azizi Ray, PhD, PharmD, UAMS
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- 274818