Optic Nerve Sheath After Extracorporeal Circulation
Study Details
Study Description
Brief Summary
The purpose of this study is to assess the influence of extracorporeal circulation during cardiac surgery on the optic nerve sheath diameter (ONSD) after the surgery.
Condition or Disease | Intervention/Treatment | Phase |
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Detailed Description
ONSD will be measured before and 1 hour after the surgery and in the morning of day 1 after the surgery. Fluid balance and lactate will be measured too. PONV will be assessed. Patients will be evaluated with MoCA test on the day before surgery and on the day 3 after the surgery for cognitive disfunction.
Study Design
Arms and Interventions
Arm | Intervention/Treatment |
---|---|
standard cardiopulmonary bypass patients 18 year or older undergoing heart surgery with standard cardiopulmonary bypass |
Diagnostic Test: ultrasound measurement of the optic nerve sheath diameter
ultrasound measurement of the optic nerve sheath diameter
Diagnostic Test: MoCA test
MoCA test is a short bedside test for measuring cognitive disfunction
|
mini-cardiopulmonary bypass patients 18 year or older undergoing heart surgery with standard mini-cardiopulmonary bypass |
Diagnostic Test: ultrasound measurement of the optic nerve sheath diameter
ultrasound measurement of the optic nerve sheath diameter
Diagnostic Test: MoCA test
MoCA test is a short bedside test for measuring cognitive disfunction
|
Outcome Measures
Primary Outcome Measures
- Ultrasound measuring of optic nerve sheath diameter baseline [Before start of surgery]
Baseline optic nerve sheath diameter measurement before start of surgery with a linear ultrasound probe (Scan) in coronal and axial plane
- Ultrasound measuring of optic nerve sheath diameter end of surgery [1 hour after the end of surgery]
Optic nerve sheath diameter measurement 1 hour after the end of surgery with a linear ultrasound probe in coronal and axial plane
- Ultrasound measuring of optic nerve sheath diameter day 1 [day 1 after the surgery]
Optic nerve sheath diameter measurement in the morning on day 1 after the surgery with a linear ultrasound probe in coronal and axial plane
Secondary Outcome Measures
- postoperative cognitive disfunction measured with the MoCA test [on the day before surgery, on day 3 after the surgery]
MoCA test is a validated test for cognitive disfunction, especially in patients who are elderly than 60 years, the study is comparing the MoCA test values on the day before surgery with the values on day 3 after the surgery
- postoperative nausea and vomiting (PONV) [during the first 24 hours after surgery]
Postoperative nausea and vomiting is common after cardiac surgery, the occurrence of postoperative nausea and vomiting will be recorded
Eligibility Criteria
Criteria
Inclusion Criteria:
- heart surgery with use of cardiopulmonary bypass
Exclusion Criteria:
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pregnancy and lactation
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neurologic disorders
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hyperthyroidism
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optic nerve disorders
Contacts and Locations
Locations
Site | City | State | Country | Postal Code | |
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1 | University medical centre Maribor | Maribor | Slovenia | 2000 |
Sponsors and Collaborators
- University Medical Centre Maribor
Investigators
None specified.Study Documents (Full-Text)
None provided.More Information
Publications
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- Ali MA, Hashmi M, Shamim S, Salam B, Siraj S, Salim B. Correlation of Optic Nerve Sheath Diameter with Direct Measurement of Intracranial Pressure through an External Ventricular Drain. Cureus. 2019 Sep 26;11(9):e5777. doi: 10.7759/cureus.5777.
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- Chen H, Ding GS, Zhao YC, Yu RG, Zhou JX. Ultrasound measurement of optic nerve diameter and optic nerve sheath diameter in healthy Chinese adults. BMC Neurol. 2015 Jul 7;15:106. doi: 10.1186/s12883-015-0361-x.
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- UKC-MB-KME-59/21