Optical Coherence Tomography Angiography Compared to Maternal Doppler in Screening for Hypertension in Pregnancy
Sponsor
Minia University (Other)
Overall Status
Recruiting
CT.gov ID
NCT05330949
Collaborator
(none)
60
1
8
7.5
Study Details
Study Description
Brief Summary
Pregnancy related hypertension is one of the most prevalent obstetric complications. The aim of the study is to evaluate the validity and sensitivity of OCT angiography in prediction of pregnancy induced hypertensive disorders in comparison to maternal doppler in the first and second trimesters of pregnancy
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
Study Design
Study Type:
Observational
Anticipated Enrollment
:
60 participants
Observational Model:
Case-Control
Time Perspective:
Prospective
Official Title:
Retinal Microvascular Changes by Optical Coherence Tomography Angiography Compared to Maternal Uterine Artry Doppler in Screening for Hypertensive Disorders in High-risk Pregnancies
Actual Study Start Date
:
Apr 1, 2022
Anticipated Primary Completion Date
:
Dec 1, 2022
Anticipated Study Completion Date
:
Dec 1, 2022
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| case group
|
Diagnostic Test: Optical coherence Tomography Angiography, Uterine artry doppler
vascular changes in retina by OCT angiography and uterine artry doppler in the first and second trimesters
|
| control
|
Diagnostic Test: Optical coherence Tomography Angiography, Uterine artry doppler
vascular changes in retina by OCT angiography and uterine artry doppler in the first and second trimesters
|
Outcome Measures
Primary Outcome Measures
- validity and sensitivity of OCT angiography [6 months]
sensitivity of OCTA in comparison to doppler in prediction of pregnancy related hypertension
Eligibility Criteria
Criteria
Ages Eligible for Study:
22 Years
to 45 Years
Sexes Eligible for Study:
Female
Inclusion Criteria:
- Pregnant women in the first and second trimesters
Exclusion Criteria:
- pregnant females with associated systemic vascular disease as diabetes, SLE
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | Minia University | Minya | Minia Governorate | Egypt | 61111 |
Sponsors and Collaborators
- Minia University
Investigators
None specified.Study Documents (Full-Text)
None provided.More Information
Publications
None provided.Responsible Party:
Mohamed Esmail Khalil Esmail,
lecturer of Ophthalmology,
Minia University
ClinicalTrials.gov Identifier:
NCT05330949
Other Study ID Numbers:
- 294-2022
First Posted:
Apr 15, 2022
Last Update Posted:
Apr 15, 2022
Last Verified:
Apr 1, 2022
Individual Participant Data (IPD) Sharing Statement:
Undecided
Plan to Share IPD:
Undecided
Additional relevant MeSH terms: